Patents by Inventor Dina KAZANOV

Dina KAZANOV has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220125824
    Abstract: Provided are nucleic acid constructs and systems which comprise (i) a first nucleic acid construct encoding a toxin operatively linked to a first promoter and at least one cancer-associated signaling responsive enhancer element; and (ii) a second nucleic acid construct encoding an anti-toxin operatively linked to a second promoter, the second promoter being stronger than the first promoter. Also provided are pharmaceutical compositions comprising same and methods of using same for treating cancer.
    Type: Application
    Filed: January 10, 2022
    Publication date: April 28, 2022
    Inventors: Nadir ARBER, Shiran SHAPIRA, Dina KAZANOV
  • Patent number: 11219636
    Abstract: Provided are nucleic acid constructs and systems which comprise (i) a first nucleic acid construct encoding a toxin operatively linked to a first promoter and at least one cancer-associated signaling responsive enhancer element; and (ii) a second nucleic acid construct encoding an anti-toxin operatively linked to a second promoter, the second promoter being stronger than the first promoter. Also provided are pharmaceutical compositions comprising same and methods of using same for treating cancer.
    Type: Grant
    Filed: May 17, 2016
    Date of Patent: January 11, 2022
    Assignee: THE MEDICAL RESEARCH, INFRASTRUCTURE AND HEALTH SERVICES FUND OF THE TEL AVIV MEDICAL CENTER
    Inventors: Nadir Arber, Shiran Shapira, Dina Kazanov
  • Publication number: 20200408761
    Abstract: A method of diagnosing high grade bladder cancer is provided. The method comprising detecting in a urine sample of a subject in need thereof expression of CD24, wherein an increase in said expression of CD24 above a predetermined threshold as compared to a control sample is indicative of said high grade bladder cancer.
    Type: Application
    Filed: February 28, 2019
    Publication date: December 31, 2020
    Applicant: The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center
    Inventors: Nadir ARBER, Shiran SHAPIRA, Dina KAZANOV
  • Patent number: 10639350
    Abstract: Provided are methods of improving wound healing in a subject by administering a therapeutically effective amount of CD24. Also provided are pharmaceutical compositions which comprise CD24 being in a formulation with a surfactant and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: May 5, 2020
    Assignee: The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center
    Inventors: Nadir Arber, Shiran Shapira, Dina Kazanov
  • Publication number: 20180221445
    Abstract: Provided are methods of improving wound healing in a subject by administering a therapeutically effective amount of CD24. Also provided are pharmaceutical compositions which comprise CD24 being in a formulation with a surfactant and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: August 10, 2016
    Publication date: August 9, 2018
    Inventors: Nadir ARBER, Shiran SHAPIRA, Dina KAZANOV
  • Publication number: 20180161358
    Abstract: Provided are nucleic acid constructs and systems which comprise (i) a first nucleic acid construct encoding a toxin operatively linked to a first promoter and at least one cancer-associated signaling responsive enhancer element; and (ii) a second nucleic acid construct encoding an anti-toxin operatively linked to a second promoter, the second promoter being stronger than the first promoter. Also provided are pharmaceutical compositions comprising same and methods of using same for treating cancer.
    Type: Application
    Filed: May 17, 2016
    Publication date: June 14, 2018
    Inventors: Nadir ARBER, Shiran SHAPIRA, Dina KAZANOV