Patents by Inventor Dinesh Mahajan

Dinesh Mahajan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydroxysteroid compounds, their intermediates, process of preparation, composition and uses thereof
    Patent number: 11542298
    Abstract: The present invention relates to novel steroidal compounds of formula (I), process for preparation of the same and composition comprising these compounds.
    Type: Grant
    Filed: March 3, 2020
    Date of Patent: January 3, 2023
    Assignee: Epirium Bio Inc.
    Inventors: Sundeep Dugar, Dinesh Mahajan, George Frederic Schreiner
  • TRIGONELLINE BASED COMPOUNDS
    Publication number: 20210047269
    Abstract: The present invention provides novel compounds with improved solubility and altered pharmacokinetic properties.
    Type: Application
    Filed: August 24, 2020
    Publication date: February 18, 2021
    Inventors: Sundeep DUGAR, Dinesh MAHAJAN, Somdutta SEN
  • HYDROXYSTEROID COMPOUNDS, THEIR INTERMEDIATES, PROCESS OF PREPARATION, COMPOSITION AND USES THEREOF
    Publication number: 20210024572
    Abstract: The present invention relates to novel steroidal compounds of formula (I), process for preparation of the same and composition comprising these compounds.
    Type: Application
    Filed: March 3, 2020
    Publication date: January 28, 2021
    Inventors: Sundeep DUGAR, Dinesh MAHAJAN, George Frederic SCHREINER
  • Trigonelline based compounds
    Patent number: 10752589
    Abstract: The present invention provides novel compounds with improved solubility and altered pharmacokinetic properties. The compounds of the present invention may be represented by Formula (I).
    Type: Grant
    Filed: March 14, 2017
    Date of Patent: August 25, 2020
    Assignee: SPHAERA PHARMA PVT. LTD.
    Inventors: Sundeep Dugar, Dinesh Mahajan, Somdutta Sen
  • Hydroxysteroid compounds, their intermediates, process of preparation, composition and uses thereof
    Patent number: 10618933
    Abstract: The present invention relates to novel steroidal compounds of formula (I), process for preparation of the same and composition comprising these compounds.
    Type: Grant
    Filed: July 23, 2015
    Date of Patent: April 14, 2020
    Assignee: EPIRIUM BIO INC.
    Inventors: Sundeep Dugar, Dinesh Mahajan, George Frederic Schreiner
  • METHOD OF CONVERTING CARBON DIOXIDE INTO CARBONYL COMPOUNDS
    Publication number: 20190284171
    Abstract: The present invention provides a method for fixing carbon dioxide gas as a carbonyl compound represented by formula (3) as depicted by FIG. 1 and comprising, purging of carbon dioxide in a solution of a nucleophile represented by the formula (1) in presence of a solvent at a temperature ranging from ?40 Degree Celsius to 35 Degree Celsius, followed by adding a reagent at temperature ranging from ?40 degree to 35 degree and thereafter adding another nucleophile represented by the formula (2) to obtain carbonyl compound represented by formula (3). The present invention can be advantageously used to obtain commercially important carbonyl compounds and clean unwanted carbon dioxide gas from the atmosphere and industrial effluents.
    Type: Application
    Filed: October 11, 2018
    Publication date: September 19, 2019
    Inventors: Dinesh MAHAJAN, Varun KUMAR, Anil RANA
  • TRIGONELLINE BASED COMPOUNDS
    Publication number: 20190077757
    Abstract: The present invention provides novel compounds with improved solubility and altered pharmacokinetic properties. The compounds of the present invention may be represented by Formula (I).
    Type: Application
    Filed: March 14, 2017
    Publication date: March 14, 2019
    Inventors: Sundeep DUGAR, Dinesh MAHAJAN, Somdutta SEN
  • Compounds as anti-tubercular agents
    Patent number: 10207993
    Abstract: The present invention relates to novel compounds of formula (1): The present invention also discloses compounds of formula (1) along with other pharmaceutical acceptable excipients and use of the compounds as anti-tubercular agents.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: February 19, 2019
    Assignees: SPHAERA PHARMA PVT. LTD., DRUG DISCOVERY RESEARCH CENTRE
    Inventors: Sundeep Dugar, Dinesh Mahajan, Santosh Kumar Rai, Kanury Rao, Varshneya Singh
  • Compounds as anti-tubercular agents
    Patent number: 10100012
    Abstract: The present invention relates to novel compounds of formula (1): The present invention also discloses compounds of formula (1) along with other pharmaceutical acceptable excipients and use of the compounds as anti-tubercular agents.
    Type: Grant
    Filed: June 1, 2015
    Date of Patent: October 16, 2018
    Assignees: SPHAERA PHARMA PVT. LTD., DRUG DISCOVERY RESEARCH CENTRE
    Inventors: Sundeep Dugar, Dinesh Mahajan, Santosh Kumar Rai, Kanury Rao, Varshneya Singh
  • Analogues of epicatechin and related polyphenols
    Patent number: 9975869
    Abstract: The present invention provides novel analogs of epicatechin and related polyphenols, their variously functionalized derivatives, process for preparation of the same, composition comprising these compounds and their method of use.
    Type: Grant
    Filed: April 4, 2014
    Date of Patent: May 22, 2018
    Assignee: SPHAERA PHARMA PVT. LTD.
    Inventors: Sundeep Dugar, Dinesh Mahajan, Kumar Santosh Rai, Sarbjit Singh, Ishwar Rakesh Patil
  • Methods of treating tumoral diseases, or bacterial or viral infections
    Patent number: 9907796
    Abstract: Novel compounds and their synthesis are described. Methods for using these compounds in the prevention or treatment of cancer, a bacterial infection or a viral infection in a subject are also described.
    Type: Grant
    Filed: September 15, 2016
    Date of Patent: March 6, 2018
    Assignee: INHIBIKASE THERAPEUTICS, INC.
    Inventors: Rhushikesh Chandrabhan Deokar, Sundeep Dugar, Dinesh Mahajan, Milton Henry Werner
  • NOVEL COMPOUNDS AS ANTI-TUBERCULAR AGENTS
    Publication number: 20170334851
    Abstract: The present invention relates to novel compounds of formula (1): The present invention also discloses compounds of formula (1) along with other pharmaceutical acceptable excipients and use of the compounds as anti-tubercular agents.
    Type: Application
    Filed: August 10, 2017
    Publication date: November 23, 2017
    Applicants: SPHAERA PHARMA PVT. LTD., DRUG DISCOVERY RESEARCH CENTRE
    Inventors: Sundeep DUGAR, Dinesh MAHAJAN, Santosh Kumar RAI, Kanury RAO, Varshneya SINGH
  • NOVEL COMPOUNDS AS ANTI-TUBERCULAR AGENTS
    Publication number: 20170183305
    Abstract: The present invention relates to novel compounds of formula (1): The present invention also discloses compounds of formula (1) along with other pharmaceutical acceptable excipients and use of the compounds as anti-tubercular agents.
    Type: Application
    Filed: June 1, 2015
    Publication date: June 29, 2017
    Applicants: SPHAERA PHARMA PVT. LTD., DRUG DISCOVERY RESEARCH CENTRE
    Inventors: Sundeep DUGAR, Dinesh MAHAJAN, Santosh Kumar RAI, Kanury RAO, Varshneya SINGH
  • HYDROXYSTEROID COMPOUNDS, THEIR INTERMEDIATES, PROCESS OF PREPARATION, COMPOSITION AND USES THEREOF
    Publication number: 20170158730
    Abstract: The present invention relates to novel steroidal compounds of formula (I), process for preparation of the same and composition comprising these compounds.
    Type: Application
    Filed: July 23, 2015
    Publication date: June 8, 2017
    Applicant: SPHAERA PHARMA PVT. LTD.
    Inventors: Sundeep DUGAR, Dinesh MAHAJAN, George Frederick SCHREINER
  • Triazine compounds
    Patent number: 9630958
    Abstract: The present invention relates to novel triazine compounds of formula (1). The present invention also discloses compounds of formula I along with other pharmaceutical acceptable excipients and use of the compounds to modulate the PI3K/mTOR pathway.
    Type: Grant
    Filed: July 23, 2013
    Date of Patent: April 25, 2017
    Assignee: SPHAERA PHARMA PTE. LTD.
    Inventors: Sundeep Dugar, Dinesh Mahajan, Frank Hollinger Peter, Amit Sharma, Vinayak Tripathi, Bilash Kuila
  • Compounds, their synthesis and their uses
    Patent number: 9556156
    Abstract: The present invention discloses novel chemical compounds obtained by causing a covalent attachment of a modifying agent of the structure provided for formula 1, to a functional group or a heteroatom of a heterocyclic ring system in chemical compound with improved chemical and biological properties. Wherein: Y is DRUG-CO; DRUG-OCO; DRUG-NRCO, and X is selected from.
    Type: Grant
    Filed: October 7, 2013
    Date of Patent: January 31, 2017
    Assignee: SPHAERA PHARMA PTE LTD.
    Inventors: Sundeep Dugar, Frank Peter Hollinger, Dinesh Mahajan, Rhushikesh Chandrabhan Deokar
  • Approach for synthesis of catechins
    Patent number: 9556140
    Abstract: A process for synthesis of enatiomerically pure or enatiomerically enriched or racemic mixture of (+ and/or ?) epicatechin and its intermediates, comprising the steps of: (i) obtaining penta-protected quercetin; (ii) reducing the penta-protected quercetin obtained from step (i); (iii) optionally deprotecting the compound of step (ii); (iv) reducing the compound obtained from step (ii) or step (iii) in the presence of a chiral/achiral reducing agent to obtain a chiral intermediate; (v) deprotecting and/or hydrogenation of the chiral intermediate obtained from step (iv) to obtain (?)-epicatechin; (vi) optionally simultaneously deprotecting and by drogenation of the compound obtained from step (ii) to obtain racemic epicatechin.
    Type: Grant
    Filed: January 27, 2014
    Date of Patent: January 31, 2017
    Assignee: Sphaera Pharma Pvt. Ltd.
    Inventors: Sundeep Dugar, Dinesh Mahajan, Kumar Santosh Rai, Vinayak Tripathi, Ishwar Rakesh Patil
  • Methods of Treating Tumoral Diseases, or Bacterial or Viral Infections
    Publication number: 20170000789
    Abstract: Novel compounds and their synthesis are described. Methods for using these compounds in the prevention or treatment of cancer, a bacterial infection or a viral infection in a subject are also described.
    Type: Application
    Filed: September 15, 2016
    Publication date: January 5, 2017
    Inventors: Rhushikesh Chandrabhan Deokar, Sundeep Dugar, Dinesh Mahajan, Milton Henry Werner
  • Compounds and compositions thereof
    Patent number: 9487500
    Abstract: Novel compounds and their synthesis are described. Methods for using these compounds in the prevention or treatment of cancer, a bacterial infection or a viral infection in a subject are also described.
    Type: Grant
    Filed: October 4, 2013
    Date of Patent: November 8, 2016
    Assignee: INHIBIKASE THERAPEUTICS, INC.
    Inventors: Rhushikesh C. Deokar, Sundeep H. Dugar, Dinesh Mahajan, Milton H. Werner
  • Triazine compounds
    Patent number: 9481670
    Abstract: The present invention relates to novel triazine compounds of formula (1), methods of their preparation, pharmaceutical compositions containing these compounds and the use of these compounds to treat proliferative disorders such as tumors and cancers and also other conditions and disorders related to or associated with dysregulation of PI3 Kinases, PI3 Kinase pathway, mTOR and/or the mTOR pathway.
    Type: Grant
    Filed: January 25, 2012
    Date of Patent: November 1, 2016
    Assignee: Sphaera Pharma PTE. Ltd.
    Inventors: Sundeep Dugar, Dinesh Mahajan, Chandraban Rhushikesh Deokar, Frank Peter Hollinger, Kamal Kishore Kapoor