Abstract: A garment for providing circulatory system disorder therapy includes a skin contacting layer, a backing layer, and a coupling. The backing layer is coupled to the skin contacting layer such that the skin contacting layer and the backing layer form a plurality of macro-chambers. A first one of the plurality of macro-chambers is partitioned into a plurality of micro-chambers. Each of the plurality of micro-chambers is in direct fluid communication with at least one other of the plurality of micro-chambers. The coupling is coupled to the backing layer and is configured to supply pressurized air directly into the first macro-chamber such that the pressurized air is delivered to a first one of the plurality of micro-chambers of the first macro-chamber.

Abstract: Automated devices provide methodologies for determining sleep conditions, which may be in conjunction with treatment of sleep disordered breathing by a pressure treatment apparatus such as a continuous positive airway pressure device. Based on a measure of respiratory airflow, respiratory characteristics are extracted to detect arousal conditions, sleep stability, sleep states and/or perform sleep quality assessments. The methodologies may be implemented for data analysis by a specific purpose computer, a monitoring device that measures a respiratory airflow and/or a respiratory treatment apparatus that provides a respiratory treatment regime based on the detected conditions.

Abstract: A method of a processor for detecting a presence of Cheyne-Stokes respiration from a respiration signal includes accessing data representative of a respiration signal. Data is assessed to detect apnea and/or hypopnea events. A cycle length histogram is determined based on the events and an incident of Cheyne-Stokes respiration is detected based on the cycle length histogram.

Abstract: Methods and apparatus provide automated controls for a respiratory pressure therapy device, such as a servo-ventilator. For example, a controller of a respiratory pressure therapy device may control application of pressure support ventilation therapy to an airway of a patient. The controller may control the respiratory pressure therapy device to auto-titrate an expiratory positive airway pressure (EPAP) of a pressure support ventilation therapy so as to maintain airway patency of the patient. The EPAP may be bounded below by a floor pressure limit. The controller may control the respiratory pressure therapy device to repeatedly adjust the floor pressure limit depending on events of interest during the auto-titration of the EPAP. Such methodologies may improve treatment for patients such as those suffering from sleep disordered breathing-comorbid hyperarousal disorders.

Abstract: A compression garment for providing circulatory-related disorder therapy includes a skin contacting layer, a second layer, and one or more connectors. The second layer is coupled to the skin contacting layer such that the skin contacting layer and the second layer form one or more independent macro-chambers partitioned into a plurality of micro-chambers. Each of the plurality of micro-chambers is in direct fluid communication with at least one other of the plurality of micro-chambers. The connectors are disposed on the second layer and are configured to supply pressurized air directly into a corresponding one of the macro-chambers such that the pressurized air is delivered to the plurality of micro-chambers. The coupling includes a weld profile that defines the macro-chambers and micro-chambers. A pneumatic spine for a compression garment including a plurality of independent air chambers for implementing circulatory-related disorder therapy.

Abstract: A garment for providing circulatory system disorder therapy includes a skin contacting layer, a backing layer, and a coupling. The backing layer is coupled to the skin contacting layer such that the skin contacting layer and the backing layer form a plurality of macro-chambers. A first one of the plurality of macro-chambers is partitioned into a plurality of micro-chambers. Each of the plurality of micro-chambers is in direct fluid communication with at least one other of the plurality of micro-chambers. The coupling is coupled to the backing layer and is configured to supply pressurized air directly into the first macro-chamber such that the pressurized air is delivered to a first one of the plurality of micro-chambers of the first macro-chamber.

Abstract: A method of a device detects a respiratory effort-related arousal in a respiratory airflow signal of a patient. The method may include computing a measure of consistency of inspiratory flow limitation over a plurality of recent breaths from the signal. The method may further include computing a measure of step change in ventilation indicating a sudden big breath. The method may further include computing a measure indicating a degree of confidence of occurrence of a respiratory effort-related arousal from the measure of consistency of inspiratory flow limitation and the measure of the step change in ventilation.

Abstract: Automated methods provide leak detection that may be implemented in a respiratory treatment apparatus. In some embodiments, the detection apparatus may automatically determine and score different types of leak events during a treatment session, including, for example, continuous mouth leak events and valve-like mouth leak events. The detection methodologies may be implemented as a data analysis of a specific purpose computer or a detection device that measures a respiratory airflow or a respiratory treatment apparatus that provides a respiratory treatment regime based on the detected leak. In some embodiments, the leak detector may determine and report a leak severity index. Such an index may combine data that quantifies different types of leak events.

Abstract: Disclosed is an apparatus for treating a respiratory disorder. The apparatus comprises a pressure device, and a controller, including at least one processor, configured to control the pressure device to: supply, upon initiation of treatment, a flow of pressurized air to the airway of a patient at a treatment pressure according to a pre-sleep profile of pressure versus time, increase, upon detection of sleep onset of the patient, the treatment pressure to a predetermined therapeutic pressure according to a bridging profile of pressure versus time, and supply the flow of pressurized air to the airway of the patient at a therapeutic pressure.

Abstract: Automated methods provide a ventilation sufficiency assessment to evaluate patient respiration. In some embodiments, a ventilation histogram maybe determined from a measure of patient respiratory flow. Based on the histogram or associated ventilation data, hypoventilation or hyperventilation occurrences may be detected. For example, a kurtosis index and/or skewness index may be calculated with the data associated with the ventilation histogram and may be evaluated as an indication of hypoventilation or hyperventilation. An assessment of the number of peaks and other features of the ventilation histogram, such as in the case of a bimodal ventilation histogram, may be implemented to detect an occurrence of ventilation insufficiency or sufficiency. The detection methodologies may be implemented by a specific purpose computer, a detection device that measures a respiratory airflow or a respiratory treatment apparatus that provides a respiratory treatment regime based on the detected ventilation sufficiency.

Abstract: Automated methods provide leak detection that may be implemented in a respiratory treatment apparatus. In some embodiments, the detection apparatus may automatically determine and score different types of leak events during a treatment session, including, for example, continuous mouth leak events and valve-like mouth leak events. The detection methodologies may be implemented as a data analysis of a specific purpose computer or a detection device that measures a respiratory airflow or a respiratory treatment apparatus that provides a respiratory treatment regime based on the detected leak. In some embodiments, the leak detector may determine and report a leak severity index. Such an index may combine data that quantifies different types of leak events.

Abstract: Methods and apparatus for treating a respiratory disorder, in one aspect, include an apparatus that delivers backup breaths at a sustained timed backup rate that is a function of the patient's spontaneous respiratory rate. Other aspects include apparatus that delivers backup breaths at a rate that gradually increases from a spontaneous backup rate to a sustained timed backup rate or, alternatively, apparatus that oscillates a treatment pressure in antiphase with the patient's spontaneous respiratory efforts when a measure indicative of ventilation is greater than a threshold.

Abstract: Apparatus and methods provide compliance management tools such as for respiratory pressure therapy. In some versions, a respiratory pressure therapy system may include one or more processors, such as of a data server, configured to communicate with a computing device and/or a respiratory pressure therapy device. The respiratory pressure therapy device may be configured to deliver respiratory pressure therapy to a patient for a session. The computing device may be associated with the patient. The processor(s) may be further configured to compute a therapy quality indicator of the session from usage data relating to the session. The therapy quality indicator may be a number derived from contributions of a plurality of usage variables for the session in the usage data. The processor(s) may be further configured to present, such as by transmitting, the therapy quality indicator to the computing device. The therapy quality indicator may promote patient compliance.

Abstract: Respiratory pressure treatment apparatus include automated methodologies for controlling changes to pressure in the presence of sleep disordered breathing events. In an example apparatus, various levels of expiratory pressure relief can provide different pressure reductions for patient comfort during expiration (333-A, 333-B, 333-C). The control parameters for these levels may be automatically modified based on the detection of an open airway. Similarly, in some embodiments, the levels may be automatically adjusted based on a detection of persistent obstruction. In still further embodiments, control parameters associated with a rise time of an early portion of an inspiratory pressure treatment may be automatically adjusted upon detection of flow limitation to permit a change to more aggressive waveforms from more comfortable waveforms for the treatment of sleep disordered breathing events.

Abstract: Automated devices provide methodologies for determining sleep conditions, which may be in conjunction with treatment of sleep disordered breathing by a pressure treatment apparatus such as a continuous positive airway pressure device. Based on a measure of respiratory airflow, respiratory characteristics are extracted to detect arousal conditions, sleep stability, sleep states and/or perform sleep quality assessments. The methodologies may be implemented for data analysis by a specific purpose computer, a monitoring device that measures a respiratory airflow and/or a respiratory treatment apparatus that provides a respiratory treatment regime based on the detected conditions.

Abstract: Methods and apparatus provide automated controls for a respiratory pressure therapy device, such as a servo-ventilator. For example, a controller of a respiratory pressure therapy device may control application of pressure support ventilation therapy to an airway of a patient. The controller may control the respiratory pressure therapy device to auto-titrate an expiratory positive airway pressure (EPAP) of a pressure support ventilation therapy so as to maintain airway patency of the patient. The EPAP may be bounded below by a floor pressure limit. The controller may control the respiratory pressure therapy device to repeatedly adjust the floor pressure limit depending on events of interest during the auto-titration of the EPAP. Such methodologies may improve treatment for patients such as those suffering from sleep disordered breathing-comorbid hyperarousal disorders.

Abstract: Automated devices provide methodologies for determining sleep conditions, which may be in conjunction with treatment of sleep disordered breathing by a pressure treatment apparatus such as a continuous positive airway pressure device. Based on a measure of respiratory airflow, respiratory characteristics are extracted to detect arousal conditions, sleep stability, sleep states and/or perform sleep quality assessments. The methodologies may be implemented for data analysis by a specific purpose computer, a monitoring device that measures a respiratory airflow and/or a respiratory treatment apparatus that provides a respiratory treatment regime based on the detected conditions.

Abstract: Respiratory pressure treatment apparatus include automated methodologies for controlling changes to pressure in the presence of sleep disordered breathing events. In an example apparatus, various levels of expiratory pressure relief can provide different pressure reductions for patient comfort during expiration (333-A, 333-B, 333-C). The control parameters for these levels may be automatically modified based on the detection of an open airway. Similarly, in some embodiments, the levels may be automatically adjusted based on a detection of persistent obstruction. In still further embodiments, control parameters associated with a rise time of an early portion of an inspiratory pressure treatment may be automatically adjusted upon detection of flow limitation to permit a change to more aggressive waveforms from more comfortable waveforms for the treatment of sleep disordered breathing events.

Abstract: A method for a device detects periodic breathing in a patient. The method may include receiving a series of event intervals bounded by apnea or hypopnea events detected in respiration of the patient, and processing, upon closure of an event interval, the event interval to determine a character of the event interval, such as any of: probably a periodic breathing cycle; probably not a periodic breathing cycle; and uninformative.

Abstract: A method of a device detects a respiratory effort-related arousal in a respiratory airflow signal of a patient. The method may include computing a measure of consistency of inspiratory flow limitation over a plurality of recent breaths from the signal. The method may further include computing a measure of step change in ventilation indicating a sudden big breath. The method may further include computing a measure indicating a degree of confidence of occurrence of a respiratory effort-related arousal from the measure of consistency of inspiratory flow limitation and the measure of the step change in ventilation.