Abstract: Various embodiments are directed to a valve switching system for selectively interconnecting components of a bioprocess installation, comprising a valve switching cassette and an actuator block. It is proposed, that the valve switching cassette comprises a perforated backer plate securing a valve membrane structure to a cassette manifold, that the actuator block comprises a drive membrane structure with at least one drive membrane and a perforated backer plate securing the drive membrane structure to an actuator block body, wherein for selectively switching valve units, an actuator of the actuator block may urge the drive membrane structure through aligned perforation holes of both backer plates into engagement with the valve membrane structure.

Abstract: A valve setup for SMB chromatography includes a cassette block, a control block, a swiveling door, and a flexible pressurizing tube. The cassette block is configured to control each of a plurality of valves when an operation surface is in close contact with a control surface of the cassette block. The swiveling door is hinged to the valve control block such that an open state of the door arranges the cassette block such that the control surface is at the operation surface of the control block, and a closed position holds the cassette block with an inner surface of the swiveling door abutting a rear surface of the cassette block opposite the control surface. The flexible pressurizing tube is arranged at the inner surface of the swiveling door so the pressurizing tube presses against the rear surface of the cassette block when the pressure in the tube is increased.

Abstract: An assembly is provided that comprises: a valve cassette block (20) comprising a plurality of valves (25) which are controllable via a control surface (24) of the valve cassette block (20); a valve control block (10) having an operation surface (11), the valve control block (10) being configured to control each of the plurality of valves when the operation surface (11) is in close contact with the control surface (24) of the valve cassette block (20) in an operation position; at least one swiveling door (30) hinged to the valve control block (20) such that an open state of the swiveling door (30) allows arranging the valve cassette block (20) into the operation position with its control surface (24) arranged at the operation surface (11) of the valve control block, while a closed position of the swiveling door (30) is configured to hold the valve cassette block (20) in the operation position with an inner surface of the swiveling door (30) abutting a rear surface (26) of the valve cassette block (20) oppos

Abstract: An assembly is provided that comprises: at least one valve cassette block (20) comprising a plurality of valves (25) which are controllable via a control surface (24) of the valve cassette block (20); a valve control block (10) having an operation surface (11), the valve control block (10) being configured to control each of the plurality of valves (25) when the operation surface (11) is in contact with the control surface (24) of the at least one valve cassette block (20), the valve control block (10) comprising at least one sliding trench (14) formed in the operation surface (11); at least one sliding component (30) configured to slidably interlock with the at least one sliding trench (14) such that the at least one sliding component (30) is movable relative to the valve control block (10) in a sliding direction parallel to the operation surface (11), at least one pulling bracket (40, 50) configured to embrace the at least one valve cassette block (20) and to interact with the at least one sliding compon

Abstract: A valve switching system for selectively interconnecting components of a bioprocess installation, comprising a valve switching cassette and an actuator block. It is proposed, that the valve switching cassette comprises a perforated sandwich plate with perforation holes, which sandwich plate is placed between the cassette manifold and the actuator block body.

Abstract: A valve switching cassette for selectively interconnecting components of a bioprocess installation, wherein the valve switching cassette comprises at least one fluid flow system of ports and fluid lines, which fluid flow system includes primary ports, communicating with primary fluid lines, and secondary ports, communicating with secondary fluid lines, wherein the valve switching cassette comprises an array of switchable valve units for selectively interconnecting the primary fluid lines with the secondary fluid lines via transfer fluid lines. It is prosed, that the valve switching cassette comprises a transfer plate with apertures and an elastically deformable membrane structure on each flat side of the transfer plate, that at least part of the primary fluid lines and secondary fluid lines are extending between the transfer plate and one of the membrane structures and that the transfer fluid lines are at least partly provided by the apertures.

Abstract: An assembly is provided that comprises at least one valve unit (20, 30) comprising a plurality of valves (25), the at least one valve unit (20, 30) having a plurality of valve unit protrusions (32) extending in a first direction and at least one valve unit fastener-engaging component (36); a valve control block (10) configured to open and close the plurality of valves (25), the valve control block (10) comprising a plurality of pins (15) extending in the first direction (A); and at least one thrust plate (40) comprising a plurality of thrust plate protrusions (42), a plurality of thrust plate apertures (44) configured to receive the plurality of pins (15) and at least one thrust plate fastener-engaging component (46); wherein: the at least one valve unit (20, 30) further comprises a plurality of fitted through-holes configured to receive the plurality of pins (15) and the at least one valve unit (20, 30) is positioned adjacent to the valve control block (10) in the first direction (A); the at least one t

Abstract: A sensor for measuring current flow includes a power generation circuit, a current measurement circuit and a microcontroller. The power generation circuit includes a current transformer that harvests energy from a load applied to the conductor and uses the harvested energy to power the current measurement circuit and microcontroller. The current measurement circuit includes a Hall effect sensor that outputs a voltage signal in response to detecting a magnetic flux generated by the flow of current through the conductor. The microcontroller calculates a current measurement based on the voltage signal received from the current measurement system. The Hall effect sensor is able to generate the voltage signal used to measure current flow at the same time that the current transformer harvests energy from the current flowing through the conductor. A fault detection system is able to alert a user to problems with the current transformer and/or the Hall effect sensor.

Abstract: A sensor for measuring current flow includes a power generation circuit, a current measurement circuit and a microcontroller. The power generation circuit includes a current transformer that harvests energy from a load applied to the conductor and uses the harvested energy to power the current measurement circuit and microcontroller. The current measurement circuit includes a Hall effect sensor that outputs a voltage signal in response to detecting a magnetic flux generated by the flow of current through the conductor. The microcontroller calculates a current measurement based on the voltage signal received from the current measurement system. The Hall effect sensor is able to generate the voltage signal used to measure current flow at the same time that the current transformer harvests energy from the current flowing through the conductor. A fault detection system is able to alert a user to problems with the current transformer and/or the Hall effect sensor.

Abstract: Various air-actuated components of a disk drive are disclosed. For instance, an air-actuated load/unload ramp may be used by a disk drive and which is movable between a parked position and an operational position. An air-actuated ramp lock may be used by a disk drive to lock a movable load/unload ramp (e.g., one that may move between a parked position and an operational position). Finally, an air-actuated head positioner assembly may be used by a disk drive to lock a head positioner assembly in its parked position. In each of these cases, air currents generated by a rotation of one or more disks used by the disk drive provide the motive force for moving the noted air-actuated component at least generally from one position to another.

Abstract: Isolation of an HDD production device such as a servo track writer from external vibration is provided. The isolated device and its nest or support are suspended in a fashion to allow one, two or three degrees of angular or rotational freedom of movement. The points of suspension are above the center of mass of the isolated device, alone or combined with its nest, and gravity will self-align the isolated device in the manner of an unforced pendulum. A relatively large moment of inertia for at least one direction of angular movement is provided, e.g., by positioning at least one suspension point spaced a relatively large distance from the center of mass to provide a large moment arm for such movement.

Abstract: Embodiments of the present invention are directed to methods of making a disk drive and related servo writers. The disk drive includes a data storage disk, an actuator arm, and a head connected to the actuator arm. The disk drive is connected to a servo writer that includes a push-arm that is configured to radially move the actuator arm relative to the disk. The method includes moving the push-arm of the servo writer a defined distance to push the actuator arm and position the head at a defined radial location on the disk. Servo fields are written through the head along an arc at the defined radial location on the disk. A sensor that contacts the actuator arm is used to generate an electrical vibration signal that is indicative of vibration between the push-arm and the actuator arm.