Abstract: The present invention relates to an antigen-binding protein, or an antigen-binding fragment thereof which binding to CEACAM6, comprising (i) a heavy chain variable domain comprising a VHCDR1 having the amino acid sequence GNTFTSYVMH; a VHCDR2 having the amino acid sequence YINPYNDGTKYNEKFKG; and a VHCDR3 having the amino acid sequence STARATPYFYAMDY and (ii) a light chain variable domain comprising a VLCDR1 having the amino acid sequence KSSQSLLWSVNQNSYLS, a VLCDR2 having the amino acid sequence GASIRES, and a VLCDR3 having the amino acid sequence QHNHGSFLPYT. The present invention also relates to compositions comprising the antigen-binding protein, or antigen-binding fragment thereof, methods of use of the antigen-binding protein, or antigen-binding fragment thereof for cancer treatment, prevention or detection and a kit comprising the antigen-binding protein, or antigen-binding fragment thereof.

Abstract: A split lens includes a first lens group including a first set of lenses, a second lens group including a second set of lenses, and at least one light shielding element. The light shielding element is disposed between the lens at the bottom position of the first lens group and the lens at the top position of the second lens group, such that a predetermined light path is formed between the first lens group and the second lens group, thereby conforming to the structure of the split lens.

Abstract: A method of forming a metal nanomaterial comprises forming a precursor solution comprising a metal precursor and a metal oxide precursor. A complexing agent is added to the precursor solution, and the metal precursor and the metal oxide precursor are hydrolyzed to form a sol. The sol is heated to form a gel, which is calcined to incorporate metal cations from the metal precursor into a metal oxide lattice from the metal oxide precursor. The calcined gel is exposed to a reducing agent to exsolve the metal from the metal oxide lattice and to form a metal nanomaterial comprising a metal and a metal oxide is formed. Additional methods of forming a metal nanomaterial are also disclosed.

Abstract: The present invention belongs to the field of additive manufacturing technology, and discloses a 4D printing method capable of in-situ regulating functional properties of nickel-titanium (NiTi) alloys and the application thereof. The method comprises the following steps: subjecting NiTi alloy bars to atomization milling to obtain NiTi alloy powder with a particle size of 15-53 ?m, placing the NiTi alloy powder in a discharge plasma assisted ball mill for discharge treatment to promote the activation of powder activity, then adding nano-sized Ni powder with a particle size of 100-800 nm to obtain mixed powder, then continuing the discharge treatment to realize the metallurgical bonding between the NiTi alloy powder and the nano-sized Ni powder to obtain the modified powder, and finally using the additive manufacturing technology to prepare and form the modified powder into a functionalized NiTi alloy.

Abstract: The present application provides use of an algal proteoglycan extract and a composition comprising the same in treating or preventing tumor, pain, inflammation or diseases mediated by inflammatory factors.

Abstract: Systems and methods are disclosed that include an operation chamber, a plasma generator having at least one plasma head disposed within the operation chamber and in proximity to a profile formed by cutting a piece of tubing, and a mechanical motion module. The plasma generator generates a plasma treatment and applies the plasma treatment via the at least one plasma head to the profile to activate material on an end surface of the profile, within a lumen of the profile, or a combination thereof. Once the material of the profile is activated by the plasma treatment, the mechanical motion module manipulates the profile to close the lumen of the profile to aseptically seal the profile.

Abstract: One or more embodiments herein can provide a process to determine dead-reckoning localization of a vehicle. An exemplary system can comprise a memory that stores computer executable components, and a processor that executes the computer executable components stored in the memory, wherein the computer executable components can comprise an obtaining component that obtains plural sensor readings defining movement of a vehicle, wherein the plural sensor readings comprise an inertial sensor reading, a kinematics sensor reading, and an odometry sensor reading, and a generation component that generates, based on the plural sensor readings, a pose value defining a position of the vehicle relative to an environment in which the vehicle is disposed. A sensing sub-system of the exemplary system can comprise an inertial measurement unit sensor, a kinematics sensor, and an odometry sensor.

Abstract: A method for fabricating a semiconductor device includes the steps of: forming a gate structure on a substrate; forming a source/drain region adjacent to the gate structure; performing a first cleaning process; performing a first rapid thermal anneal (RTA) process to remove oxygen cluster in the substrate; forming a metal layer on the source/drain region; and performing a second RTA process to transform the metal layer into a silicide layer.

Abstract: The present disclosure provides for an arrangement of components within a hearable device, such as earbuds, to reduce H field coupling for E noise improvement. A battery is positioned above a magnet and speaker, such that the battery is not coaxially aligned with either the magnet or the speaker. An internal positive tab of a battery is positioned farthest from a speaker yoke, while an internal negative tab of the battery is closer to the speaker yoke. Magnetic flux poles of a contact magnet have different contributions for electric field coupling.

Abstract: Various systems and methods are provided for performing soft entity resolution. A plurality of data objects are retrieved from a plurality of data stores to create aggregated data objects for one or more entities. One or more retrieved data objects may be associated with the same entity, based at least in part upon one or more attribute types and attribute values of the data objects. In response to a determination that the one or more of the retrieved data objects should be associated with the same entity, metadata is generated that associates the data objects with the entity, the metadata being stored separately from the data objects, such that the underlying data objects remain unchanged. In addition, one or more additional attributes may be determined for the entity, based upon the data objects associated with the entity.

Abstract: A sacubitril intermediate, a preparation method therefor, and use thereof. A key intermediate N-Boc amino alcohol represented by formula (10) or formula (10-a) can be efficiently prepared. The intermediate can be used to prepare a neutral endopeptidase (NEP) inhibitor or a prodrug thereof, particularly a NEP inhibitor comprising a skeleton of ?-amino-?-biphenyl-?-methylalkanoic acid or ester, such as sacubitril. Also provided are intermediates for preparing formula (10) or formula (10-a).

Abstract: A communication method and apparatus includes a terminal that receives first control information from a network device. The first control information includes a first field. The first field indicates single-carrier scheduling or the multi-carrier scheduling. When the first field indicates the single-carrier scheduling, the terminal communicates with the network device on one scheduled carrier. Alternatively, when the first field indicates the multi-carrier scheduling, the terminal communicates with the network device on a plurality of scheduled carriers. According to the method and the apparatus in this application, the first field in the first control information may explicitly or implicitly indicate the single-carrier scheduling or the multi-carrier scheduling, and the network device does not need to additionally send a notification message, thereby reducing air interface overheads.

Abstract: A mass flow controller and methods of providing for mass flow control are provided. A mass flow controller includes a control valve configured to control flow of a fluid in a flow path. A first flow sensor detects a first set of fluid flow parameters, and a second flow sensor detects a second set of fluid flow parameters. The first and second flow sensors are of distinct flow measurement types. The mass flow controller further includes a controller configured to determine a set of first mass flow rates based on the first set of fluid flow parameters detected by the first flow sensor and calibrate the second flow sensor based on the determined set of mass flow rates of the first mass flow sensor and the second set of fluid flow parameters.

Abstract: A multi-frequency based data sending method includes: obtaining data to-be-sent; obtaining binary data by performing binary conversion on the data to-be-sent; obtaining at least one data fragment by performing data segmentation on the binary data; determining at least one sending frequency according to the number of bits of each data fragment; determining a sending frequency corresponding to each data fragment from the at least one sending frequency according to an arrangement position of each data fragment in the binary data; obtaining at least one conversion result by performing data conversion on each data fragment according to a preset conversion table and the sending frequency corresponding to each data fragment; and sending each conversion result to a data receiving end in order at the sending frequency corresponding to each conversion result.

Abstract: A window cleaning robot includes a main body including a top shell and a bottom shell. The top shell and the bottom shell define an internal space of the main body and the bottom shell includes a plurality of air inlets. At least two driving mechanisms are disposed between the two driving mechanisms. An air pump is disposed in the internal space and configured to extract air, through the inlets of the bottom shell, between the two driving mechanisms to create negative pressure to form a vacuum area located between the two driving mechanisms. An accommodating portion is configured to accommodate the air pump and an air tube, disposed in the internal space, includes an air inlet end coupled to an opening of the accommodating portion and an air outlet end coupled to an air exhaust opening toward the driving mechanism. The air inlet end of the air tube is configured to receive the extracted air and the extracted air is then exhausted toward the driving mechanism via the air tube and the air exhaust opening.

Abstract: An example gesture detection method includes detecting at a first time a first touch on a touch panel, where the first touch covers a first area of the touch panel, and then determining whether the first touch is within a track region that surrounds a fingerprint sensing region. The method includes determining whether the first touch is within the fingerprint sensing region, the fingerprint sensing region including a sensing surface of a fingerprint sensor. The method includes determining a first fraction of the fingerprint sensing region covered by the first touch and determining whether the first fraction exceeds a first threshold. The first threshold is a majority of the fingerprint sensing region. The method includes determining a second fraction of all of the first area that is within the fingerprint sensing region and determining whether the second fraction exceeds a second threshold, where the second threshold is a fraction indicative of a majority of an area associated with the corresponding touch.

Abstract: Disclosed are system, method and/or computer program product embodiments for improving the performance of a machine learning based algorithm used to provide a user experience to a user via a media device. An embodiment selects a first set of hyperparameter values, implements a first iteration of the algorithm based on the first set of hyperparameter values, utilizes the first iteration of the algorithm to provide a first user experience to the user, determines a response of the user to the first user experience, selects, by a hyperparameter tuning ML model implemented as a contextual multi-arm bandit model or a reinforcement learning model and based on at least the response of the user, a second set of hyperparameter values, implements a second iteration of the algorithm based on the second set of hyperparameter values, and utilizes the second iteration of the algorithm to provide a second user experience to the user.

Abstract: Provided are a time-domain resource determination method and apparatus, and a terminal device. The method includes: a terminal device determines a first slot set within a first period according to a first time division duplexing (TDD) configuration in radio resource control (RRC) signaling or a second TDD configuration in a physical sidelink broadcast channel (PSBCH); and the terminal device selects some slots from the first slot set according to a first bitmap, wherein the slots constitute time-domain resources in a resource pool.

Abstract: This application provides a resource scheduling method and a communication apparatus. The method includes: A network device sends a plurality of pieces of configuration information to a terminal device, where the plurality of pieces of configuration information include first configuration information and second configuration information, the first configuration information is for configuring scheduling information of a multi-carrier co-scheduling manner to be sent in a first cell, and the second configuration information is for configuring a resource of a second cell to be scheduled in the multi-carrier co-scheduling manner; and the network device sends first scheduling information to the terminal device in the first cell, where the first scheduling information is for scheduling resources of a plurality of cells, and the plurality of cells include the second cell or the first cell and the second cell. In this way, resource utilization and resource scheduling efficiency are improved.