Abstract: Described herein is N-[4-[4-(4-morpholinyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]-4-[[3(R)-[(1-oxo-2-propen-1-yl)amino]-1-piperidinyl]methyl]-2-pyridinecarboxamide (Compound A) (Formula I), including crystalline forms, solvates, and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions or pharmaceutical formulations that include the compound, as well as methods of using the compound, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, diabetes, and inflammatory diseases or conditions.

Abstract: The present application provides a bulk acoustic resonator and a preparation method thereof, and a filter. The bulk acoustic resonator includes: a substrate, wherein the substrate includes a first semiconductor layer, an insulating layer and a second semiconductor layer, which are stacked in sequence; the surface of the second semiconductor layer is etched to form a groove, and the groove penetrates through the second semiconductor layer; and a protection part is formed in the groove, and a vertical section of the groove has a smooth contour.

Abstract: The invention belongs to the technical field of harmonic contribution evaluation, and particularly relates to a system for tracing harmonic sources based on a cloud-edge-terminal collaboration and a method thereof, comprising: terminal module, collecting and transmitting real-time harmonic data to edge module; edge module, comprising plurality of edge computing servers deployed for the transformer substations and the transformer districts by units, realizing hierarchical control between edge computing servers according to voltage levels, and transmitting harmonic sources tracing task through hierarchical interactions between the edge computing servers; the edge computing server receiving harmonic sources tracing service request performs the tracing task, and feeds tracing result back to central module; and, central module, comprising cloud server receiving harmonic sources tracing service request initiated by user, determining edge computing server offloaded by the request, storing final tracing result from e

Abstract: The present disclosure relates to the field of electronic measurements, and particularly to a measurement assembly of guided wave radar level gauge with high-temperature and high-pressure sealed-compensation type, includes an gauge isolation enclosure, and an upper sealing structure is mounted at a lower part of the gauge isolation enclosure, a heat dissipation section is mounted between the upper sealing structure and a middle sealing structure, and a lower sealing structure is mounted at a lower part of the middle sealing structure; a housing is disposed to sleeve the middle sealing structure, a flange is connected outside the housing, a guide cylinder is connected to a lower part of the housing, and a compensation structure and a support member are disposed in the guide cylinder. The present disclosure has the advantageous effect of adopting a multi-layer sealing design and a tightness verification design.

Abstract: The present invention relates to compounds of formula (I), wherein R1 to R3, A, Q1, Q2, W and X are as described herein, and their pharmaceutically acceptable salt thereof, and compositions including the compounds and methods of using the compounds.

Abstract: A display module and a display device. The display module includes: a display panel including a display surface and a non-display surface arranged opposite to each other; a support layer arranged on the non-display surface of the display panel, the support layer having a first surface away from the display panel, and at least part of the first surface is provided with a first shape portion arranged in a predetermined direction; and a rotating shaft having a second shape portion in a circumferential direction, the support layer and the display panel arranged around an outer circumference of the rotating shaft, the first shape portion of the first surface engaged with the second shape portion of the rotating shaft.

Abstract: A method of tuning parameters for image signal processing is provided. The method includes capturing at least one raw image. The method further includes generating a first rendered image by rendering the raw image based on a first parameter value set, and generating a second rendered image by rendering the raw image based on a second parameter value set. The method further includes calculating a first image quality score set for the first rendered image, and calculating a second image quality score set for the second rendered image. The method further includes generating a third parameter value set based on the first parameter value set, the second parameter value set, the first image quality score set, and the second image quality score set.

Abstract: There are provided methods and apparatuses for a control flow execution-guided deep learning framework for binary code vulnerability detection. Reinforcement learning is to enhance the branching decision at every program state transition and create a dynamic environment to learn the dependency between a vulnerability and certain program states. An implicitly defined neural network enables state transition until convergence, which captures the structural information at a higher level.

Abstract: The present application provides bicyclic amines of Formula (I): and their pharmaceutically acceptable salts thereof, that are inhibitors of cyclin-dependent kinase 2 (CDK2), as well as pharmaceutical compositions thereof, and methods of treating cancer using the same.

Abstract: A sustained-release gel with insoluble salt as pH adjuster, and its preparation method and application are disclosed. The sustained-release gel is obtained by dissolving polymer in an aqueous solvent, followed by blending and compounding the alkaline inclusion and the insoluble salt crystalline powder. The insoluble salt is at solid state and thus has thus a large amount as the reservoir of the pH adjuster. The preparation is injectable, can be converted into gel state after being injected into organism, and realizes the sustained release of the inclusion at the injection site. The presence of the insoluble salt reduces the solubility of the inclusion in the gel by releasing the free salt sustainably and thus adjusting the pH inside the gel in a sustained manner. The burst release of the inclusion out of the gel is significantly alleviated.

Abstract: A data transmission method and apparatus, and a related device, and may be used in the internet of vehicles, for example, V2X, LTE-V, or V2V, or may be used in fields such as D2D, intelligent driving, and intelligent connected vehicle. A network device may send first downlink control information to a first terminal device and a second terminal device, to indicate the first terminal device and the second terminal device to perform user cooperative transmission in a first stage. After the transmission in the first stage is completed, the network device sends second downlink control information to the first terminal device and the second terminal device, to indicate the first terminal device and the second terminal device to perform user cooperative transmission in a second stage. The network device uses a two-level scheduling manner to improve transmission efficiency in the second stage.

Abstract: An amplified optical beam is provided to a region that receives a target including target material, an interaction between the amplified optical beam and the target converting at least some of the target material from a first form to a second form to form a light-emitting plasma; first data comprising information related to the amplified optical beam is accessed; second data comprising information related to the light-emitting plasma is accessed; and an amount of the target material converted from the first form to the second form is determined. The determination is based on at least the first data and the second data, and the second form of the target material is less dense than the first form of the target material.

Abstract: Disclosed are devices, kits, apparatus, and methods for rapid homogenous cell staining and imaging.

Abstract: The present disclosure may provide imaging methods, systems and storage media. The imaging methods may include: obtaining first imaging data acquired by an imaging device, wherein the first imaging data includes data corresponding to a plurality of cardiac cycles; and performing image reconstruction on data corresponding to the plurality of cardiac cycles in the first imaging data to acquire one or more cardiac cines. Each cardiac cine of the one or more cardiac cines may include cardiac images of a plurality of phases in at least one cardiac cycle.

Abstract: The present invention provides an absorption-desorption based Carnot battery designed to achieve a high-efficiency, large-density, and low-loss conversion battery system for power-heat-power purpose. Based on the rational operating strategies, the current Carnot battery system design demonstrates outstanding energy storage density and round-trip efficiency, while the self-discharging loss is minimal even after prolonged standby time. The battery system of the present invention also enables further designs with flexibility in adopting different operating modes for versatile functions to provide electricity, heating, and cooling.

Abstract: Example aspects include techniques for implementing a high-frequency attention network for single image super-resolution. These techniques may include extracting a plurality of features from an original image input into a CNN to generate a feature map, and restoring one or more high-frequency details of the original image via an efficient residual block (ERB) and a high-frequency attention block (HFAB) configured to assign a scaling factor to one or more high-frequency areas. In addition, the techniques may include generating reconstruction input information by performing an element-wise operation on the one or more high-frequency details and cross-connection information from the feature map and performing, by the CNN, an enhancement operation on the reconstruction input information to generate an enhanced image.

Abstract: Provided herein are opioid receptor modulators and pharmaceutical compositions comprising said compounds.

Abstract: Systems and methods for presence-based account data association with devices are disclosed. For example, a presence event may be detected and details of the presence event may be utilized to determine whether and how to initiate, maintain, or end an account-association session associated with a secondary device. A current session status and a determination as to whether a primary device is associated with a previously-utilized primary account identifier for the secondary device may be used to determine whether connection notifications should be sent and/or whether the secondary device should be within a threshold distance from a primary device to establish the account-association session.

Abstract: A full-automatic detection apparatus and system for important zoonotic pathogen, and a control method therefor. The full-automatic detection apparatus for important zoonotic pathogen includes: a base capable of moving; an air collection device, configured to collect a to-be-detected sample in air along with the movement of the base; a nucleic acid detection and analysis device, configured to detect the to-be-detected sample collected by the air collection device to determine whether an infectious pathogen exists in the to-be-detected sample; an intelligent mobile device, configured to plan and control a moving path of the base; and a control device, configured to control the intelligent mobile device to plan and control the moving path of the base and to control a sampling period of the air collection device according to a control instruction of the terminal, and transmit a detection result from the nucleic acid detection and analysis device to the terminal.

Abstract: The present disclosure provides a method and apparatus for return control of a swimming pool cleaning robot, and an electronic device and a computer storage medium thereof. The method includes: in response to a trigger of a return instruction, acquiring a current position of the swimming pool cleaning robot in a map for a swimming pool; and generating a return path according to a reachable block in the map for the swimming pool, a predetermined return position, and the current position, and controlling the swimming pool cleaning robot to return from the current position to the predetermined return position on the basis of the return path. Therefore, the swimming pool cleaning robot is controlled to automatically return to a designated position of the swimming pool, such that use smartness of the swimming pool cleaning robot is improved, and use experience of a user is enhanced.