Abstract: The present application provides a method of training a deep learning model. A specific implementation solution of the method of training the deep learning model includes: determining, according to first training data for a current training round, a first target parameter required to be written into a target memory in a first network parameter required by an embedding of the first training data, wherein the target memory is a memory contained in a target processor; determining a remaining storage slot in the target memory according to a first mapping relationship between a storage slot of the target memory and a network parameter; and writing, in response to the remaining storage slot meeting a storage requirement of the first target parameter, the first target parameter into the target memory so that a computing core contained in the target processor adjusts the first network parameter according to the first training data.

Abstract: Disclosed herein are methods, compositions, and kits for treating a subject in need of a treatment for a cancer. The method comprises administering to the subject a CDK8/19 inhibitor and a mTOR inhibitor.

Abstract: An advantageous morphic form of Compound 1 which is also known as CFT7455 and is (S)-3-(6-(4-(morpholinomethyl)benzyl)-2-oxobenzo[cd]indol-1(2H)-yl)piperidine-2,6-dione and methods to prepare Compound 1 for therapeutic applications are provided. This invention also provides new dosage regimens for administering Compound 1.

Abstract: An application of potassium ion (K+) channel blocker in preparation of drugs for treating liver fibrosis is provided, which relates to the field of medical technologies. The K+ channel blocker is sotalol, the sotalol is originally used as an antiarrhythmic drug in clinic and has a property of inhibiting K+ channels. Experiments show that sotalol can effectively inhibit liver fibrosis and reduce expression of fibrosis-related protein alpha-smooth muscle actin (?-SMA), specifically by regulating expression and/or function of autophagy and epithelial-mesenchymal transition (EMT) molecules to achieve inhibition of hepatic stellate cell (HSC) fibrosis, so as to provide a new drug choice for clinical treatment of the liver fibrosis.

Abstract: The present disclosure discloses a dynamically traceable privacy-preserving distributed threshold signature system and method, which are applied to an environment composed of multiple signer modules, multiple aggregator modules, multiple notary modules, multiple tracer modules and a blockchain module; where the signer module signs data, encrypts a signature and uploads encrypted signature to the blockchain module; the aggregator module receives the encrypted signatures from the blockchain module and aggregates them into a synthetic signature, and at the same time sends a corresponding transaction to the blockchain module; the notary module locates the synthetic signature in the blockchain module and partially decrypts the synthetic signature into multiple synthetic signature fragments; the tracer module aggregates synthetic signature fragments and traces a set of signers; and the blockchain module consists of multiple nodes and is responsible for receiving transactions sent by each module.

Abstract: A display substrate and a display apparatus. The display substrate includes a display area provided with pixel circuits arranged in an array and a non-display area provided with M light emitting driving circuits, M control driving circuits and M reset driving circuits. Odd-numbered light emitting driving circuits are electrically connected with first and second light emitting clock signal lines, and even-numbered light emitting driving circuits are connected with third and fourth light emitting clock signal lines; and/or, odd-numbered control driving circuits are electrically connected with first and second control clock signal lines, and even-numbered control driving circuits are connected with third and fourth control clock signal lines; and/or, odd-numbered reset driving circuits are electrically connected with first and second reset clock signal lines, and even-numbered reset driving circuits are connected with third and fourth reset clock signal lines.

Abstract: The present invention relates to the technical field of wind turbine energy storage, and discloses an offshore wind turbine generator set having a compressed energy storage system, including a wind turbine generator set, an air compressor set, an air expander set, a first motor generator, a three-in-one motor which are provided in a wind turbine generator compartment, and a combined air storage device provided outside the wind turbine generator compartment, in which the first motor generator is alternatively connected to the wind turbine generator set or the air compressor set, the air compressor set is coaxially connected to the air expander set by means of a three-in-one motor, the combined air storage device includes a first air storage device provided in a tower barrel and a second air storage device provided on the sea, an input end of the combined air storage device is connected to the air compressor set, and an output end of the combined air storage device is connected to the air expander set.

Abstract: Provided is an antibody-drug conjugate based on a microtubule inhibitor. Specifically provided are a compound as represented by formula (I), a pharmaceutically acceptable salt thereof, a stereoisomer thereof, or a solvate of the compound, the pharmaceutically acceptable salt thereof or the stereoisomer thereof. The present invention further relates to an antibody-drug conjugate formed by means of connecting a targeting moiety with the compound as represented by formula (I), the pharmaceutically acceptable salt thereof, the stereoisomer thereof, or the solvate of the compound, the pharmaceutically acceptable salt thereof or the stereoisomer thereof via a thioether bond.

Abstract: An application of a channel blocker in preparation of drugs for treating and/or preventing liver fibrosis is provided, belonging to the field of biomedical technology. A new use of phenytoin sodium is provided. It is demonstrated that at the cell level, the phenytoin sodium can improve liver fibrosis by regulating autophagy and thus affecting the activation of hepatic stellate cells. In this situation, the efficacy of the phenytoin sodium on liver fibrosis is verified at the animal level by establishing a disease model, and the phenytoin sodium can be used to prepare drugs for treating and/or preventing liver fibrosis.

Abstract: Disclosed is a dynamic regulation method for a lane changing decision point of a CAV dedicated lane in a diverging area of an expressway, applied to the diverging area of the expressway in which the CAV dedicated lane is provided at an inner side of a road. Vehicles traveling in the CAV dedicated lane are all CAVs. Both the CAVs and human-driven vehicles can travel in ordinary lanes. The method calculates the lane changing decision points of diversion vehicles in the CAV dedicated lane at current time using corresponding algorithms based on a relationship between the lane changing decision points of the CAV dedicated lane and traffic efficiency and a traffic safety.

Abstract: The technology is directed to artificial intelligence (AI) powered tools that can enhance existing digital video components and simplify and automate the creation of new digital video components. The technology includes a digital video component creation tool that leverages existing assets to generate digital video components, a voice-over tool that can add voice-overs, generated from text to video components, and a video component evaluation tool that can evaluate video components for conformity with attributes associated with metrics for video creatives.

Abstract: A plurality of electric heater elements are positioned within a core of an electric heater for heating the core to charge the core with stored thermal energy. A first air path extends through the core between an air input opening and an air output opening in a housing. An air supply conduit connects to a supply of an external air flow; an outlet end of an air output conduit is connected to a heated air outlet conduit, for outputting heated air from the electric heater. A bypass conduit connects first and second junctions and defines a second air path external of the core. A temperature sensor senses temperature of heated air. An air flow control valve mechanism variably controls a flow rate of air flow along a conduit based on a temperature of the heated air measured by the temperature sensor, thereby controlling a flow rate along the air paths.

Abstract: A photosensitive device includes an integrated circuit structure and a plurality of photodiodes disposed on the integrated circuit structure. The photodiodes respectively includes a first material layer and a second material layer overlapping on the first material layer and extending beyond the first material layer to directly contact a surface of the integrated circuit structure. The first material layer and the second material layer are made of two-dimensional semiconductor materials.

Abstract: The present application relates to a method and a circuit for dynamic range control based on peak level and RMS level double-level detection. The method includes: processing an input signal by an equalizer, to obtain an equalized signal; detecting a signal peak level and a signal RMS level of the equalized signal, to obtain the signal peak level and the signal RMS level; adjusting a parameter configuration of a dynamic range controller according to the signal peak level and the signal RMS level; adjusting a dynamic gain of the dynamic range controller according to the parameter configuration, and adjusting the equalized signal by using the adjusted gain, and then outputting the adjusted equalized signal. The method can not only control the dynamic range of the signal but also improve the clipping distortion of the signal.

Abstract: In one embodiment, a nozzle assembly includes a body with an internal surface forming an internal cavity within the body. The assembly also includes a gas inlet disposed within the body, a fluid inlet disposed within the body and a mixing chamber disposed within the internal cavity of the body, such that an annular gap is formed between the internal surface and an exterior surface of the mixing chamber, the mixing chamber may include: a mixing body region within the mixing chamber; one or more gas ports fluidly connecting the gas inlet to the mixing chamber, the gas ports tangentially aligned with an interior surface of the mixing chamber; a fluid port in fluid communication with the fluid inlet of the body and the mixing body region of the mixing chamber; and an outlet in fluid communication with the mixing body region configured to deliver a fluid mixture.

Abstract: In one embodiment, a nozzle assembly includes a body with an internal surface forming an internal cavity within the body. The assembly also includes a gas inlet disposed within the body, a fluid inlet disposed within the body and a mixing chamber disposed within the internal cavity of the body, such that an annular gap is formed between the internal surface and an exterior surface of the mixing chamber, the mixing chamber may include: a mixing body region within the mixing chamber; one or more gas ports fluidly connecting the gas inlet to the mixing chamber, the gas ports tangentially aligned with an interior surface of the mixing chamber; a fluid port in fluid communication with the fluid inlet of the body and the mixing body region of the mixing chamber; and an outlet in fluid communication with the mixing body region configured to deliver a fluid mixture.

Abstract: Systems and methods relating to multi-beam forming networks using an antenna array. A matrix circuit for feeding elements of an antenna array to produce multiple beams is provided. To address beam squint issues, beam squint is mitigated by using a series of phase shifters with specific phase-delay performances between the matrix circuit and the antenna array elements. A linearly increasing or decreasing phase difference in the signals fed into adjacent antenna array elements across the array mitigates or eliminates beam squint in the resulting multiple beams. The phase shifters are programmed to provide this increasing or decreasing phase differences.

Abstract: An intracavity frequency doubling fiber laser includes pump sources, optical beam combiners and a bidirectional optical amplifier; a first fiber collimator, a first optical polarization rotating device, a polarizer, a laser frequency doubling device and a laser cavity mirror being arranged on one side of the bidirectional optical amplifier along an optical path in sequence; a second fiber collimator, a polarization beam splitting device, a second optical polarization rotating device and a reflection device being arranged on the other side of the bidirectional optical amplifier along the optical path in sequence; the disclosure has small size and low cost, which can output different wavebands of frequency-doubled lasers by replacing components.

Abstract: Pseudomonas and a use thereof are provided. The preservation number of the Pseudomonas is CGMCC No. 22583. The growth temperature of the Pseudomonas is 37-45° C. Under a medium-high temperature oil reservoir condition, the Pseudomonas can be denatured from a non-viscosity fluid to a multifunctional oil-extraction bacterial solution having both surface activity and viscoelasticity, and also has the functions of expanding the swept volume and improving the oil washing efficiency. The recovery ratio is increased by more than 20% in a physical simulation experiment.

Abstract: A method for tuning a plurality of image signal processor (ISP) parameters of a camera includes performing a first iteration. The first iteration includes extracting image features from an initial image, arranging a tuning order of the plurality of ISP parameters of the camera according to at least the plurality of ISP parameters and the image features, tuning a first set of the ISP parameters according to the tuning order to generate a first tuned set of the ISP parameters, and replacing the first set of the ISP parameters with the first tuned set of the ISP parameters in the plurality of ISP parameters to generate a plurality of updated ISP parameters.