Abstract: Provided are antibodies specific for the heparan sulfate binding site of Receptor for Advanced Glycation Endproducts (RAGE). Also provided are methods for treating of conditions in which RAGE is involved comprising administration of the antibodies to an individual in need of treatment.

Abstract: In general, the subject matter described in this disclosure can be embodied in methods, devices, and program products for modifying interactions between a mobile device and a peripheral device based on proximity. The mobile device monitors a wireless communication channel and receives a transmission from the peripheral device over the channel indicating that the mobile device is located within a first zone of proximity to the peripheral device. The mobile device determines distance values between the devices. When the mobile device determines that a distance value satisfies a threshold value, the mobile device visually indicates that it is within a second zone of proximity to the peripheral device. As a result of the mobile device receiving data from the peripheral device using a second communication protocol, the mobile device determines that it is located within a third zone of proximity to the peripheral device, and performs an action.

Abstract: A conversation agent is described. An example method includes receiving a user request from a user interface of a conversation agent; determining a predicted intent of the user request; selecting a prompt template from a plurality of prompt templates corresponding to respective intents based on the predicted intent of the user request; generating a prompt using the prompt template and the user request; processing the prompt using a generative language model to generate an output; and displaying, on the user interface, a response to the user request generated based on the output.

Abstract: Provided herein are small molecule compounds, including non-anticoagulant heparan sulfate oligosaccharide molecules, having anti-inflammatory properties and capable of interacting with high mobility group box 1 (HMGB1) proteins in a manner sufficient to affect an interaction between the HMGB1 protein and a receptor for advanced glycation end products (RAGE). Also provided herein are methods of treating Paracetamol (APAP) overdose in subjects.

Abstract: Provided are a surface treatment method, a sequencing method, and a kit for nucleic acid molecule extension. The surface treatment method comprises: contacting a phosphate compound with a surface bound with an oligonucleotide, wherein the phosphate compound comprises a compound having a structural formula represented by formula (1) and/or formula (2). With regard to the problem that bases are prone to random adsorption on the surface of the sequencing chip in the sequencing process, it has been unexpectedly discovered that compounds with a specific structure can compete with virtual terminator bases in the sequencing process for adsorption on the surface of the sequencing chip, thus reducing the random adsorption of bases on the surface of the sequencing chip, reducing the resultant sequencing error rate, and improving the sequencing throughput.

Abstract: Features described herein generally relate to enhancing functionality of electronic devices. Particularly, a notification is received from a wearable device that includes a position of the wearable device within an area, a determination is made that the wearable device is located within a predetermined distance from a controllable device, a graphical user interface page that includes buttons is sent to the wearable device, an indication that a button of the buttons has been activated is received from the wearable device, and a command signal that includes an instruction is sent to the controllable device. In this way, functionality of electronic devices can be extended with wearable devices.

Abstract: In general, the subject matter described in this disclosure can be embodied in methods, devices, and program products for modifying interactions between a mobile device and a peripheral device based on proximity. The mobile device monitors a wireless communication channel and receives a transmission from the peripheral device over the channel indicating that the mobile device is located within a first zone of proximity to the peripheral device. The mobile device determines distance values between the devices. When the mobile device determines that a distance value satisfies a threshold value, the mobile device visually indicates that it is within a second zone of proximity to the peripheral device. As a result of the mobile device receiving data from the peripheral device using a second communication protocol, the mobile device determines that it is located within a third zone of proximity to the peripheral device, and performs an action.

Abstract: In general, the subject matter described in this disclosure can be embodied in methods, devices, and program products for modifying interactions between a mobile device and a peripheral device based on proximity. The mobile device monitors a wireless communication channel and receives a transmission from the peripheral device over the channel indicating that the mobile device is located within a first zone of proximity to the peripheral device. The mobile device determines distance values between the devices. When the mobile device determines that a distance value satisfies a threshold value, the mobile device visually indicates that it is within a second zone of proximity to the peripheral device. As a result of the mobile device receiving data from the peripheral device using a second communication protocol, the mobile device determines that it is located within a third zone of proximity to the peripheral device, and performs an action.

Abstract: Provided herein are small molecule compounds, including non-anticoagulant heparan sulfate oligosaccharide molecules, having anti-inflammatory properties and capable of interacting with high mobility group box 1 (HMGB1) proteins in a manner sufficient to affect an interaction between the HMGB1 protein and a receptor for advanced glycation end products (RAGE). Also provided herein are methods of treating Paracetamol (APAP) overdose in subjects.

Abstract: A method includes receiving, by a first computing device (110) and from a second computing device (118), using a short-range wireless communication unit of the first computing device (110), data including state information of the second computing device (118) and identification information for the second computing device (118). The method also includes, responsive to a distance between the first computing device (110) and the second computing device (118) satisfying a threshold distance, determining a particular template graphical user interface from a plurality of template graphical user interfaces. The method also includes determining one or more operations the second computing device (118) is configured to perform. The method further includes outputting a graphical user interface (114) associated with the remote computing device (118).

Abstract: Features described herein generally relate to enhancing functionality of electronic devices. Particularly, a notification is received from a wearable device that includes a position of the wearable device within an area, a determination is made that the wearable device is located within a predetermined distance from a controllable device, a graphical user interface page that includes buttons is sent to the wearable device, an indication that a button of the buttons has been activated is received from the wearable device, and a command signal that includes an instruction is sent to the controllable device. In this way, functionality of electronic devices can be extended with wearable devices.

Abstract: Provided herein are small molecule compounds, including non-anticoagulant heparan sulfate oligosaccharide molecules, having anti-inflammatory properties and capable of interacting with high mobility group box 1 (HMGB1) proteins in a manner sufficient to affect an interaction between the HMGB1 protein and a receptor for advanced glycation end products (RAGE). Also provided herein are methods of treating Paracetamol (APAP) overdose in subjects.

Abstract: A method performed by a head-mounted device can include, based on a front-facing camera included in the head-mounted device capturing an image of a wearable device, configuring the head-mounted device to receive input via the wearable device, determining that a gesture received by the wearable device includes a request to launch an application, and, in response to determining that the gesture includes the request to launch the application, launching the application.

Abstract: A method performed by a head-mounted device can include, based on a front-facing camera included in the head-mounted device capturing an image of a wearable device, configuring the head-mounted device to receive input via the wearable device, determining that a gesture received by the wearable device includes a request to launch an application, and, in response to determining that the gesture includes the request to launch the application, launching the application.

Abstract: Features described herein generally relate to enhancing functionality of electronic devices. Particularly, a notification is received from a wearable device that includes a position of the wearable device within an area, a determination is made that the wearable device is located within a predetermined distance from a controllable device, a graphical user interface page that includes buttons is sent to the wearable device, an indication that a button of the buttons has been activated is received from the wearable device, and a command signal that includes an instruction is sent to the controllable device. In this way, functionality of electronic devices can be extended with wearable devices.

Abstract: A remote control device for controlling devices in an environment can utilize an environment map and location information to accurately determine an intended device to provide control for multiple devices in an environment. The environment mapping can be performed using the remote control device including a plurality of sensors. A spatial map can be generated for an environment along with location information for controllable devices within the environment. The spatial map and location information can be stored on the remote control device. The mapping can allow the remote control device to quickly group devices or drag and drop content from one type of device to another type of device. The remote control device can perform search queries based on combinations of image and audio data in some examples.

Abstract: Provided are antibodies specific for the heparan sulfate binding site of Receptor for Advanced Glycation Endproducts (RAGE). Also provided are methods for treating of conditions in which RAGE is involved comprising administration of the antibodies to an individual in need of treatment.

Abstract: A method includes receiving, by a first computing device (110) and from a second computing device (118), using a short-range wireless communication unit of the first computing device (110), data including state information of the second computing device (118) and identification information for the second computing device (118). The method also includes, responsive to a distance between the first computing device (110) and the second computing device (118) satisfying a threshold distance, determining a particular template graphical user interface from a plurality of template graphical user interfaces. The method also includes determining one or more operations the second computing device (118) is configured to perform. The method further includes outputting a graphical user interface (114) associated with the remote computing device (118).

Abstract: In general, the subject matter described in this disclosure can be embodied in methods, devices, and program products for modifying interactions between a mobile device and a peripheral device based on proximity. The mobile device monitors a wireless communication channel and receives a transmission from the peripheral device over the channel indicating that the mobile device is located within a first zone of proximity to the peripheral device. The mobile device determines distance values between the devices. When the mobile device determines that a distance value satisfies a threshold value, the mobile device visually indicates that it is within a second zone of proximity to the peripheral device. As a result of the mobile device receiving data from the peripheral device using a second communication protocol, the mobile device determines that it is located within a third zone of proximity to the peripheral device, and performs an action.