Patents by Inventor Dingding ZHAO

Dingding ZHAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acid library construction method and application thereof in analysis of abnormal chromosome structure in preimplantation embryo
    Patent number: 12649919
    Abstract: Provided are a nucleic acid library construction method and an application thereof in the analysis of an abnormal chromosomal structure of a preimplantation embryo. Enzymatic cleavage is performed by means of combining a first endonuclease and a second endonuclease to capture a DNA sequence within a fixed fragment range. The specific sequences captured are then sequenced. When the average genome sequencing depth is greater than or equal to 3×, an SNP analysis can be performed in the entire range of the genome in order to perform detection of balanced translocation of the embryo and the like by means of a linkage analysis of a family-line sample.
    Type: Grant
    Filed: April 15, 2021
    Date of Patent: June 9, 2026
    Assignee: SUZHOU BASECARE MEDICAL DEVICE CO., LTD
    Inventors: Dingding Zhao, Yan Mao, Lingyin Kong, Bo Liang
  • NUCLEIC ACID LIBRARY CONSTRUCTION METHOD AND APPLICATION THEREOF IN ANALYSIS OF ABNORMAL CHROMOSOME STRUCTURE IN PREIMPLANTATION EMBRYO
    Publication number: 20230250421
    Abstract: Provided are a nucleic acid library construction method and an application thereof in the analysis of an abnormal chromosomal structure of a preimplantation embryo. Enzymatic cleavage is performed by means of combining a first endonuclease and a second endonuclease to capture a DNA sequence within a fixed fragment range. The specific sequences captured are then sequenced. When the average genome sequencing depth is greater than or equal to 3×, an SNP analysis can be performed in the entire range of the genome in order to perform detection of balanced translocation of the embryo and the like by means of a linkage analysis of a family-line sample.
    Type: Application
    Filed: April 15, 2021
    Publication date: August 10, 2023
    Applicant: SUZHOU BASECARE MEDICAL DEVICE CO., LTD.
    Inventors: Dingding ZHAO, Yan MAO, Lingyin KONG, Bo LIANG