Patents by Inventor Dingding ZHOU

Dingding ZHOU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical composition comprising and immune checkpoint inhibitors for treatment of colon cancer
    Patent number: 12569522
    Abstract: A pharmaceutical composition comprising an effective amount of a live strain of Sutterella wadsworthensis deposited under DSM No: 14016 and immune checkpoint inhibitor (ICIs) selected from the group consisting of a PD-1 monoclonal antibody, a PD-L1 monoclonal antibody, and a CTLA-4 monoclonal antibody, together with a pharmaceutically acceptable carrier, for use in the treatment of colon cancer. The therapeutic effect of the composition is enhanced, as evidenced by increased overall survival time and increased progression-free survival time. The results show that Sutterella wadsworthensis in the composition significantly improves the efficacy of ICIs in the treatment of tumors.
    Type: Grant
    Filed: June 4, 2025
    Date of Patent: March 10, 2026
    Assignee: Xiangya Hospital of Central South University
    Inventors: Wei Zhang, Yongchao Gao, Li Yang, Dingding Zhou, Weihua Huang, Honghao Zhou
  • PHARMACEUTICAL COMPOSITION COMPRISING SUTTERELLA WADSWORTHENSIS AND IMMUNE CHECKPOINT INHIBITORS FOR TREATMENT OF COLON CANCER
    Publication number: 20250302886
    Abstract: A pharmaceutical composition comprising an effective amount of a live strain of Sutterella wadsworthensis deposited under DSM No: 14016 and immune checkpoint inhibitor (ICIs) selected from the group consisting of a PD-1 monoclonal antibody, a PD-L1 monoclonal antibody, and a CTLA-4 monoclonal antibody, together with a pharmaceutically acceptable carrier, for use in the treatment of colon cancer. The therapeutic effect of the composition is enhanced, as evidenced by increased overall survival time and increased progression-free survival time. The results show that Sutterella wadsworthensis in the composition significantly improves the efficacy of ICIs in the treatment of tumors.
    Type: Application
    Filed: June 4, 2025
    Publication date: October 2, 2025
    Inventors: Wei ZHANG, Yongchao GAO, Li YANG, Dingding ZHOU, Weihua HUANG, Honghao ZHOU