Patents by Inventor Dingguo Liu

Dingguo Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating a disease or condition associated with abnormal angiogenesis
    Patent number: 8912148
    Abstract: The present invention provides methods of treating (including preventing) a disease or condition associated with abnormal angiogenesis in a subject include administering a therapeutically effective amount of an AA targeting compound of the invention to the subject. The AA targeting compounds comprise AA targeting agent-linker conjugates which are linked to a combining site of an antibody.
    Type: Grant
    Filed: August 13, 2012
    Date of Patent: December 16, 2014
    Assignee: Covx Technology Ireland, Ltd.
    Inventors: Curt Bradshaw, Abhijit Bhat, Jing Yu Lai, Venkata Doppalapudi, Dingguo Liu
  • ANTI-ANGIOGENIC COMPOUNDS
    Publication number: 20120321591
    Abstract: The present invention provides various uses of VEGF binding peptides, including methods to treat disorders associated with abnormal angiogenesis.
    Type: Application
    Filed: August 27, 2012
    Publication date: December 20, 2012
    Inventors: Venkata Ramana Doppalapudi, Jing-Yu Lai, Bin Liu, Dingguo Liu, Joel Desharnais, Abhijit Suresh Bhat, Yanwen Fu, Bryan Douglas Oates, Gang Chen, Curt William Bradshaw
  • METHODS OF TREATING A DISEASE OR CONDITION ASSOCIATED WITH ABNORMAL ANGIOGENESIS
    Publication number: 20120301431
    Abstract: The present invention provides methods of treating (including preventing) a disease or condition associated with abnormal angiogenesis in a subject include administering a therapeutically effective amount of an AA targeting compound of the invention to the subject. The AA targeting compounds comprise AA targeting agent-linker conjugates which are linked to a combining site of an antibody.
    Type: Application
    Filed: August 13, 2012
    Publication date: November 29, 2012
    Inventors: Curt Bradshaw, Abhijit Bhat, Jing Yu Lai, Venkata Doppalapudi, Dingguo Liu
  • Anti-angiogenic compounds
    Patent number: 8293714
    Abstract: The present invention provides VEGF binding peptides. In addition, the invention provides VEGF peptides conjugated to antibodies alone and in conjunction with other anti-angiogenic molecules. Various uses of the peptides and compounds are provided, including methods to treat disorders associated with abnormal angiogenesis.
    Type: Grant
    Filed: April 29, 2009
    Date of Patent: October 23, 2012
    Assignee: Covx Technology Ireland, Ltd.
    Inventors: Venkata Ramana Doppalapudi, Jing-Yu Lai, Bin Liu, Dingguo Liu, Joel Desharnais, Abhijit Suresh Bhat, Yanwen Fu, Bryan Douglas Oates, Gang Chen, Curt William Bradshaw
  • Anti-angiogenic compounds
    Patent number: 8288349
    Abstract: The present invention provides AA targeting compounds which comprise AA targeting agent-linker conjugates which are linked to a combining site of an antibody. Various uses of the compounds are provided, including methods to treat disorders connected to abnormal angiogenesis.
    Type: Grant
    Filed: November 12, 2007
    Date of Patent: October 16, 2012
    Assignee: Covx Technology Ireland, Ltd.
    Inventors: Curt William Bradshaw, Abhijit Suresh Bhat, Jing-Yu Lai, Venkata R. Doppalapudi, Dingguo Liu
  • ANTI-ANGIOGENIC COMPOUNDS
    Publication number: 20100003267
    Abstract: The present invention provides VEGF binding peptides. In addition, the invention provides VEGF peptides conjugated to antibodies alone and in conjunction with other anti-angiogenic molecules. Various uses of the peptides and compounds are provided, including methods to treat disorders associated with abnormal angiogenesis.
    Type: Application
    Filed: April 29, 2009
    Publication date: January 7, 2010
    Inventors: Venkata Ramana Doppalapudi, Jing-Yu Lai, Bin Liu, Dingguo Liu, Joel Desharnais, Abhijit Suresh Bhat, Yanwen Fu, Bryan Douglas Oates, Gang Chen, Curt William Bradshaw
  • Bisphenyl compounds useful as vitamin D3 receptor agonists
    Publication number: 20060025474
    Abstract: The present invention discloses bisphenyl compounds of the formula: wherein R1, R2, R3, R4, R5, R6, X, Y, W are defined herein after. These compounds are useful as pharmaceuticals.
    Type: Application
    Filed: March 8, 2005
    Publication date: February 2, 2006
    Inventors: David Wallace, Thomas Arrhenius, Anna Russell, Dingguo Liu, Amy Xing, Sovouthy Tith, Zheng Hou, Tadakatsu Takahashi, Yoshiyuki Ono, Hirotaka Kashiwagi, Kazuki Shimizu, Hitoshi Ikura