Patents by Inventor Dino Dina

Dino Dina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biodegradable immunomodulatory formulations and methods for use thereof
    Patent number: 8124590
    Abstract: The invention provides new compositions and methods for immunomodulation of individuals. Immunomodulation is accomplished by administration of immunomodulatory polynucleotide/microcarrier (IMP/MC) complexes. The IMP/MC complexes may be covalently or non-covalently bound, and feature a polynucleotide comprising at least one immunostimulatory sequence bound to a biodegradable microcarrier or nanocarrier.
    Type: Grant
    Filed: June 19, 2007
    Date of Patent: February 28, 2012
    Assignee: Dynavax Technologies Corporation
    Inventors: Gary Van Nest, Stephen F. Tuck, Karen L. Fearon, Dino Dina
  • Chimeric immunomodulatory compounds and methods of using the same—IV
    Patent number: 8114418
    Abstract: The invention provides immunomodulatory compounds and methods for immunomodulation of individuals using the immunomodulatory compounds.
    Type: Grant
    Filed: October 30, 2006
    Date of Patent: February 14, 2012
    Assignee: Dynavax Technologies Corporation
    Inventors: Karen L. Fearon, Dino Dina, Stephen F. Tuck
  • Chimeric immunomodulatory compounds and methods of using the same
    Patent number: 8003115
    Abstract: The invention provides immunomodulatory compounds and methods for immunomodulation of individuals using the immunomodulatory compounds.
    Type: Grant
    Filed: August 10, 2007
    Date of Patent: August 23, 2011
    Assignee: Dynavax Technologies Corporation
    Inventors: Karen L. Fearon, Dino Dina, Stephen F. Tuck
  • Biodegradable immunomodulatory formulations and methods for use thereof
    Publication number: 20110038896
    Abstract: The invention provides new compositions and methods for immunomodulation of individuals. Immunomodulation is accomplished by administration of immunomodulatory polynucleotide/microcarrier (IMP/MC) complexes. The IMP/MC complexes may be covalently or non-covalently bound, and feature a polynucleotide comprising at least one immunostimulatory sequence bound to a biodegradable microcarrier or nanocarrier.
    Type: Application
    Filed: June 19, 2007
    Publication date: February 17, 2011
    Applicant: Dynavax Technologies Corporation
    Inventors: Gary Van Nest, Stephen Tuck, Karen L. Fearon, Dino Dina
  • IMMUNOMODULATORY COMPOSITIONS, FORMULATIONS, AND METHODS FOR USE THEREOF
    Publication number: 20100291218
    Abstract: The invention provides new compositions and methods for immunomodulation of individuals. Immunomodulation is accomplished by administration of immunomodulatory polynucleotide/microcarrier (IMO/MC) complexes comprising 3-6mer immunomodulatory oligonucleotides. The IMO/MC complexes may be covalently or non-covalently bound. Also provided are immunomodulatory compositions comprising a 3-6mer IMO encapsulated in an MC.
    Type: Application
    Filed: March 2, 2009
    Publication date: November 18, 2010
    Inventors: Karen L. FEARON, Dino DINA
  • Chimeric immunomodulatory compounds and methods of using the same—III
    Patent number: 7785610
    Abstract: The invention provides immunomodulatory compounds and methods for immunomodulation of individuals using the immunomodulatory compounds.
    Type: Grant
    Filed: December 23, 2002
    Date of Patent: August 31, 2010
    Assignee: Dynavax Technologies Corporation
    Inventors: Karen L. Fearon, Dino Dina, Stephen F. Tuck
  • IMMUNOSTIMULATORY SEQUENCE OLIGONUCLEOTIDES AND METHODS OF USING THE SAME
    Publication number: 20100184834
    Abstract: The invention provides immunomodulatory polynucleotides and methods for immunomodulation of individuals using the immunomodulatory polynucleotides.
    Type: Application
    Filed: September 24, 2009
    Publication date: July 22, 2010
    Inventors: Dino DINA, Karen L. Fearon, Jason Marshall
  • Immunostimulatory sequence oligonucleotides and methods of using the same
    Patent number: 7745606
    Abstract: The invention provides immunomodulatory polynucleotides and methods for immunomodulation of individuals using the immunomodulatory polynucleotides.
    Type: Grant
    Filed: December 18, 2003
    Date of Patent: June 29, 2010
    Assignee: Dynavax Technologies Corporation
    Inventors: Dino Dina, Karen L. Fearon, Jason Marshall
  • CHIMERIC IMMUNOMODULATORY COMPOUNDS AND METHODS OF USING THE SAME-II
    Publication number: 20090317480
    Abstract: The invention provides immunomodulatory compounds and methods for immunomodulation of individuals using the immunomodulatory compounds.
    Type: Application
    Filed: October 1, 2008
    Publication date: December 24, 2009
    Inventors: Karen L. Fearon, Dino Dina, Stephen F. Tuck
  • Purified pol DNA, a recombinant DNA construct for expression of HIV pol polypeptide sequences and a cell containing such construct
    Patent number: 7527925
    Abstract: Polynucleotide sequences are provided for the diagnosis of the presence of retroviral infection in a human host associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome, for expression of polypeptides and use of the polypeptides to prepare antibodies, where both the polypeptides and antibodies may be employed as diagnostic reagents or in therapy, e.g., vaccines and passive immunization. The sequences provide detection of the viral infectious agents associated with the indicated syndromes and can be used for expression of antigenic polypeptides.
    Type: Grant
    Filed: May 17, 1995
    Date of Patent: May 5, 2009
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Paul A. Luciw, Dino Dina, Kathelyn Steimer, Ray Sanchez Pescador, Carlos George-Nascimento, Deborah Parkes, Rob Hallewell, Philip J. Barr, Martha Truett
  • Method for expressing HIV polypeptides
    Patent number: 7442525
    Abstract: Polynucleotide sequences are provided for the diagnosis of the presence of retroviral infection in a human host associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome, for expression of polypeptides and use of the polypeptides to prepare antibodies, where both the polypeptides and antibodies may be employed as diagnostic reagents or in therapy, e.g., vaccines and passive immunization. The sequences provide detection of the viral infectious agents associated with the indicated syndromes and can be used for expression of antigenic polypeptides.
    Type: Grant
    Filed: May 17, 1995
    Date of Patent: October 28, 2008
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Paul A. Luciw, Dino Dina, Kathelyn Steimer, Ray Sanchez Pescador, Carlos George-Nascimento, Deborah Parkes, Rob Hallewell, Philip J. Barr, Martha Truett
  • Recombinant DNA construct for HIV envelope polypeptides and polypeptides produced thereby
    Patent number: 7425428
    Abstract: Polynucleotide sequences are provided for the diagnosis of the presence of retroviral infection in a human host associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome, for expression of polypeptides and use of the polypeptides to prepare antibodies, where both the polypeptides and antibodies may be employed as diagnostic reagents or in therapy, e.g., vaccines and passive immunization. The sequences provide detection of the viral infectious agents associated with the indicated syndromes and can be used for expression of antigenic polypeptides.
    Type: Grant
    Filed: May 17, 1995
    Date of Patent: September 16, 2008
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Paul A. Luciw, Dino Dina, Kathelyn Steimer, Ray Sanchez Pescador, Carlos George-Nascimento, Deborah Parkes, Rob Hallewell, Philip J. Barr, Martha Truett
  • IMMUNOMODULATORY POLYNUCLEOTIDES AND METHODS OF USING THE SAME
    Publication number: 20080207550
    Abstract: The invention provides immunomodulatory polynucleotides and methods for immunomodulation of individuals using the immunomodulatory polynucleotides.
    Type: Application
    Filed: December 21, 2007
    Publication date: August 28, 2008
    Inventors: Karen L. Fearon, Dino Dina
  • Recombinant DNA constructs for GAG polypeptides and polypeptides produced thereby
    Patent number: 7408053
    Abstract: Polynucleotide sequences are provided for the diagnosis of the presence of retroviral infection in a human host associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome, for expression of polypeptides and use of the polypeptides to prepare antibodies, where both the polypeptides and antibodies may be employed as diagnostic reagents or in therapy, e.g., vaccines and passive immunization. The sequences provide detection of the viral infectious agents associated with the indicated syndromes and can be used for expression of antigenic polypeptides.
    Type: Grant
    Filed: May 17, 1995
    Date of Patent: August 5, 2008
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Paul A. Luciw, Dino Dina
  • Chimeric immunomodulatory compounds and methods of using the same
    Publication number: 20080181909
    Abstract: The invention provides immunomodulatory compounds and methods for immunomodulation of individuals using the immunomodulatory compounds.
    Type: Application
    Filed: August 10, 2007
    Publication date: July 31, 2008
    Inventors: Karen L. Fearon, Dino Dina, Stephen F. Tuck
  • Human immunodeficiency virus (HIV) nucleotide sequences
    Patent number: 7393949
    Abstract: Polynucleotide sequences are provided for the diagnosis of the presence of retroviral infection in a human host associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome, for expression of polypeptides and use of the polypeptides to prepare antibodies, where both the polypeptides and antibodies may be employed as diagnostic reagents or in therapy, e.g., vaccines and passive immunization. The sequences provide detection of the viral infectious agents associated with the indicated syndromes and can be used for expression of antigenic polypeptides.
    Type: Grant
    Filed: May 17, 1995
    Date of Patent: July 1, 2008
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Paul A. Luciw, Dino Dina, Kathelyn Steimer, Ray Sanchez Pescador, Carlos George-Nascimento, Deborah Parkes, Rob Hallewell, Philip J. Barr, Martha Truett
  • Immunomodulatory formulations and methods for use thereof
    Publication number: 20070258994
    Abstract: The invention provides new compositions and methods for immunomodulation of individuals. Immunomodulation is accomplished by administration of immunomodulatory polynucleotide/microcarrier (IMP/MC) complexes. The IMP/MC complexes may be covalently or non-covalently bound, and feature a polynucleotide comprising at least one immunostimulatory sequence bound to a nonbiodegradable microcarrier or nanocarrier.
    Type: Application
    Filed: February 7, 2007
    Publication date: November 8, 2007
    Inventors: Gary Van Nest, Stephen Tuck, Karen Fearon, Dino Dina
  • Antigenic composition comprising an HIV gag or env polypeptide
    Patent number: 7285271
    Abstract: Polynucleotide sequences are provided for the diagnosis of the presence of retroviral infection in a human host associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome, for expression of polypeptides and use of the polypeptides to prepare antibodies, where both the polypeptides and antibodies may be employed as diagnostic reagents or in therapy, e.g., vaccines and passive immunization. The sequences provide detection of the viral infectious agents associated with the indicated syndromes and can be used for expression of antigenic polypeptides.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: October 23, 2007
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Paul A. Luciw, Dino Dina
  • HIV immunoassays using synthetic envelope polypeptides
    Patent number: 7273695
    Abstract: Polynucleotide sequences are provided for the diagnosis of the presence of retroviral infection in a human host associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome, for expression of polypeptides and use of the polypeptides to prepare antibodies, where both the polypeptides and antibodies may be employed as diagnostic reagents or in therapy, e.g., vaccines and passive immunization. The sequences provide detection of the viral infectious agents associated with the indicated syndromes and can be used for expression of antigenic polypeptides.
    Type: Grant
    Filed: July 8, 1993
    Date of Patent: September 25, 2007
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Paul A. Luciw, Dino Dina
  • Human immunodeficiency virus (HIV) nucleotide sequences
    Patent number: RE41158
    Abstract: Polynucleotide sequences are provided for the diagnosis of the presence of retroviral infection in a human host associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome, for expression of polypeptides and use of the polypeptides to prepare antibodies, where both the polypeptides and antibodies may be employed as diagnostic reagents or in therapy, e.g., vaccines and passive immunization. The sequences provide detection of the viral infectious agents associated with the indicated syndromes and can be used for expression of antigenic polypeptides.
    Type: Grant
    Filed: January 12, 2009
    Date of Patent: March 2, 2010
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Paul Luciw, Dino Dina