Patents by Inventor Dionne Montviliski

Dionne Montviliski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing Imiquimod
    Patent number: 7323568
    Abstract: The present invention provides a process for preparing 4-amino-1-isobutyl-1H-imidazo[4,5-c]quinoline (Imiquimod) of formula (I). The process comprises heating 4-chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline of formula (II) with formamide, and optionally with bubbling of gaseous ammonia to afford Imiquimod of formula (I). According to the present invention, by using this process and novel purification methods, essentially as described herein, highly pure Imiquimod is obtained.
    Type: Grant
    Filed: December 12, 2005
    Date of Patent: January 29, 2008
    Assignee: Chemagis Ltd.
    Inventors: Vladimir Naddaka, Shady Saeed, Dionne Montviliski, Lior Zelikovitch, Oded Arad, Joseph Kaspi
  • Process for preparing Imiquimod
    Publication number: 20070135640
    Abstract: The present invention provides a process for preparing 4-amino-1-isobutyl-1H-imidazo[4,5-c]quinoline (Imiquimod) of formula (I). The process comprises heating 4-chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline of formula (II) with formamide, and optionally with bubbling of gaseous ammonia to afford Imiquimod of formula (I). According to the present invention, by using this process and novel purification methods, essentially as described herein, highly pure Imiquimod is obtained.
    Type: Application
    Filed: December 12, 2005
    Publication date: June 14, 2007
    Applicant: Chemagis Ltd.
    Inventors: Vladimir Naddaka, Shady Saeed, Dionne Montviliski, Lior Zelikovitch, Oded Arad, Joseph Kaspi
  • Process for preparing 1-methylindazole-3-carboxylic acid
    Patent number: 7060841
    Abstract: The invention provides a process for preparing 1-methylindazole-3-carboxylic acid of formula (I): which comprises reacting a methylating agent with indazole-3-carboxylic acid of formula (VI): in the presence of an alkaline earth metal oxide or alkoxide in an appropriate solvent. Also provided is a process for producing Granisetron, using the method of the present invention for producing 1-methylindazole-3-carboxylic acid.
    Type: Grant
    Filed: June 3, 2003
    Date of Patent: June 13, 2006
    Assignee: Chemagis Ltd.
    Inventors: Vladimir Naddaka, Shadi Saeed, Dionne Montviliski, Oded Arad, Joseph Kaspi
  • Process for preparing 1-methylindazole-3-carboxylic acid
    Publication number: 20040248960
    Abstract: The invention provides a process for preparing 1-methylindazole-3-carboxylic acid of formula (I): 1
    Type: Application
    Filed: June 3, 2003
    Publication date: December 9, 2004
    Applicant: CHEMAGIS LTD.
    Inventors: Vladimir Naddaka, Shadi Saeed, Dionne Montviliski, Oded Arad, Joseph Kaspi