Patents by Inventor Dipakranjan Mal

Dipakranjan Mal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production of a hexahydronaphthalenone compound
    Patent number: 4543428
    Abstract: The compound 6-acetyl-4a,5,6,7,8,8a-hexahydro-1(4H)-naphthalenone, and preparation thereof beginning from 2-(2-hydroxyethyl)bicyclo[2.2.2] oct-5-ene.
    Type: Grant
    Filed: June 8, 1984
    Date of Patent: September 24, 1985
    Assignee: Oregon Graduate Center for Study & Research
    Inventors: Frank M. Hauser, Dipakranjan Mal
  • Method of synthesizing a late-stage intermediate to 11-deoxydaunorubicin and 11-deoxyadriamycin, and two precursors to the object intermediate
    Patent number: 4515720
    Abstract: Preparation of 9-acetyl-6-hydroxy-4-methoxy-7,8,9,10-tetrahydronaphthacene-5,12-dione (the object intermediate), and precursor compounds to the object intermediate. Preparation of the object intermediate according to the invention begins from 2-(2-hydroxyethyl)-bicyclo[2.2.2]oct-5-ene, wherein the latter is converted to 6-acetyl-4a,5,6,7,8,8a-hexahydro-1(4H) naphthalenone (one of the two precursor compounds) which is subsequently reacted with a phenylsulfonyl isobenzofuranone to furnish, regiospecifically, 9-acetyl-5,12-dihydroxy-4-methoxy-6(11H)-hexahydronaphthacenone (the other of the two precursor compounds). Heating the hexahydronaphthacenone in dimethylforamide under an oxygen atmosphere gives the object intermediate.
    Type: Grant
    Filed: March 11, 1983
    Date of Patent: May 7, 1985
    Assignee: Oregon Graduate Center for Study & Research
    Inventors: Frank M. Hauser, Dipakranjan Mal