Patents by Inventor Dipan B. Ray

Dipan B. Ray has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synergistic binder composition, method for making same, and tablets of an active and said binder having advantageous hardness and friability
    Patent number: 8168219
    Abstract: Tablets of a pharmaceutical, nutritional or vitamin active compound or composition, e.g. a poorly compressible drug are made by direct compression using a synergistic binder composition of co-processed (a) copolymer of vinylpyrrolidone (VP) and vinyl acetate (VA) and (b) microcrystalline cellulose (MCC), in a wt. ratio of (a):(b) of 1-30:99-70, which is spray dried to provide a readily compressible excipient binder powder for such active. The tablets obtained herein have advantageous hardness and friability at an acceptable compression force.
    Type: Grant
    Filed: November 30, 2005
    Date of Patent: May 1, 2012
    Assignee: ISP Investments Inc.
    Inventors: Rama Haldar, Dipan B. Ray, Timothy G. Bee, Sidney Etienne, Su-Jane Cheng
  • Meltable Binder for Melt Granulation and/or Pelletization
    Publication number: 20100104656
    Abstract: A low melting binder composition for preparation of pharmaceutical tablets and/or granules which comprises a polymer and a hydrophobic meltable binder.
    Type: Application
    Filed: March 19, 2008
    Publication date: April 29, 2010
    Inventors: Paul Wan Sia Heng, Wai See Cheong, Zhi Hui Loh, Dipan B. Ray, Rama Haldar, Yolande Anthony
  • Binder composition and method for processing poorly compressible drugs into tablets of predetermined hardness and friability
    Patent number: 7704528
    Abstract: Tablets of a poorly compressible drug are made by direct compression using a binder composition which is a polymer, preferably a copolymer of polyvinylpyrrolidone (PVP) and vinyl acetate (VA), having a defined glass transition temperature (Tg), admixed with a plasticizer, e.g. an organic ester or polyol, which reduces the Tg of the copolymer by at least 10° C. The binder composition and the drug are directly compressed into a tablet of predetermined hardness and friability, and at an acceptable compression force.
    Type: Grant
    Filed: August 15, 2003
    Date of Patent: April 27, 2010
    Assignee: ISP Investments Inc.
    Inventors: Rama Haldar, John Zamora, Dipan B. Ray, William Drefko, Greg Dubrowny, Sidney Etienne
  • Process and apparatus for forming agglomerates of a powder composition of an active and binder
    Patent number: 7534381
    Abstract: A process and apparatus for forming agglomerates of a powder composition of an active and binder such as a homopolymer or copolymer which includes passing the composition through a hot roller compactor to heat said binder material above its glass transition temperature.
    Type: Grant
    Filed: September 14, 2005
    Date of Patent: May 19, 2009
    Assignee: ISP Investments Inc.
    Inventors: Rama Haldar, Dipan B. Ray, William Drefko, Sidney Etienne
  • Binder composition and method for processing poorly compressible drugs into tablets of predetermined hardness and friability
    Publication number: 20040224015
    Abstract: Tablets of a poorly compressible drug are made by direct compression using a binder composition which is a polymer, preferably a copolymer of polyvinylpyrrolidone (PVP) and vinyl acetate (VA), having a defined glass transition temperature (Tg), admixed with a plasticizer, e.g. an organic ester or polyol, which reduces the Tg of the copolymer by at least 10° C. The binder composition and the drug are directly compressed into a tablet of predetermined hardness and friability, and at an acceptable compression force.
    Type: Application
    Filed: August 15, 2003
    Publication date: November 11, 2004
    Applicant: ISP INVESTMENTS INC.
    Inventors: Rama Haldar, John Zamora, Dipan B. Ray, William Drefko, Greg Dubrowny, Sidney Etienne