Patents by Inventor Dipankar BHANDARI

Dipankar BHANDARI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF REDUCING THE IMMUNOSTIMULATORY PROPERTIES OF IN VITRO TRANSCRIBED RNA
    Publication number: 20240102065
    Abstract: The present invention provides a method of reducing the immunostimulatory properties of an in vitro transcribed RNA by producing the in vitro transcribed RNA comprising a 3? terminal A nucleotide. Hereby, the circular DNA template used to generate the in vitro transcribed RNA has been linearized using a type IIS endonuclease. The invention further provides pharmaceutical compositions comprising the vitro transcribed RNA comprising a 3? terminal A nucleotide according to the invention for use in therapy.
    Type: Application
    Filed: January 26, 2022
    Publication date: March 28, 2024
    Applicant: CureVac SE
    Inventors: Moritz THRAN, Andreas THESS, Fabian EBER, Dipankar BHANDARI