Patents by Inventor Dipesh Parikh

Dipesh Parikh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170296510
    Abstract: The present invention relates to a method of forming a concentrated solution of first and second pharmacologically active ingredients which involves: providing a solid eutectic composition of the first and second pharmacologically active ingredients; providing a first solvent; and dissolving the eutectic composition in the first solvent; wherein the first and second pharmacologically active ingredients are independently selected from ?2 agonists, muscarinic antagonists, anticholinergics, corticosteroids, methylxanthine compounds and salts, esters, polymorphs, hydrates or solvates thereof. A solution obtainable by this method is also described, along with an ampoule for a nebuliser and a pressurised metered dose inhaler comprising the solution. The solution is useful in the treatment of respiratory diseases.
    Type: Application
    Filed: September 24, 2015
    Publication date: October 19, 2017
    Inventors: John Burns, Dipesh Parikh
  • Publication number: 20170275781
    Abstract: This invention provides a process for increasing the crystallinity of at least one solid material which is less than 100% crystalline, comprising contacting said solid material with solvent in which the solid material is insoluble or poorly soluble (a non-solvent); and applying ultrasound to the solid material when in contact with said non-solvent.
    Type: Application
    Filed: April 18, 2017
    Publication date: September 28, 2017
    Inventors: Graham Ruecroft, Dipesh Parikh, David Hipkiss
  • Patent number: 9682038
    Abstract: Pharmaceutical compositions comprising multi-component crystalline particles suitable for use in inhalation therapy and for delivery by oral or nasal inhalation are provided, wherein said compositions additionally comprise particles of at least one additional active agent. Also provided are methods of preparation of the compositions and their use in medicine.
    Type: Grant
    Filed: January 29, 2014
    Date of Patent: June 20, 2017
    Assignee: Prosonix Limited
    Inventors: John Burns, Dipesh Parikh
  • Patent number: 9637840
    Abstract: This invention provides a process for increasing the crystallinity of at least one solid material which is less than 100% crystalline, comprising contacting said solid material with solvent in which the solid material is insoluble or poorly soluble (a non-solvent); and applying ultrasound to the solid material when in contact with said non-solvent.
    Type: Grant
    Filed: July 20, 2009
    Date of Patent: May 2, 2017
    Assignee: Prosonix Limited
    Inventors: Graham Ruecroft, Dipesh Parikh, David Hipkiss
  • Publication number: 20160081924
    Abstract: This invention provides a pharmaceutical composition comprising a eutectic composition of two pharmacologically active ingredients for delivery to the lung by inhalation. This invention also provides a pharmaceutical composition comprising a eutectic composition of two pharmacologically active ingredients for the treatment of respiratory disease.
    Type: Application
    Filed: November 25, 2015
    Publication date: March 24, 2016
    Inventors: Graham Ruecroft, Dipesh Parikh
  • Patent number: 9278323
    Abstract: A process for preparing an emulsion or a dispersion comprising crystalline particles of at least one active principal that comprises contacting a solution of at least one solute in a solvent or mixture of solvents in a first flowing stream with a non-solvent in a second flowing stream wherein the non-solvent and solvent are not miscible with each other, so as to form an emulsion or a dispersion. Super saturation is brought about by suitable means, and the emulsion or dispersion is subjected to ultrasonic irradiation to mediate crystal nucleation.
    Type: Grant
    Filed: June 17, 2008
    Date of Patent: March 8, 2016
    Assignee: Prosonix Limited
    Inventors: Graham Ruecroft, James Robinson, Dipesh Parikh
  • Patent number: 9220708
    Abstract: This invention provides a pharmaceutical composition comprising a eutectic composition of two pharmacologically active ingredients for delivery to the lung by inhalation. This invention also provides a pharmaceutical composition comprising a eutectic composition of two pharmacologically active ingredients for the treatment of respiratory disease.
    Type: Grant
    Filed: August 8, 2012
    Date of Patent: December 29, 2015
    Assignee: Prosonix Limited
    Inventors: Graham Ruecroft, Dipesh Parikh
  • Publication number: 20150366804
    Abstract: Pharmaceutical compositions comprising multi-component crystalline particles suitable for use in inhalation therapy and for delivery by oral or nasal inhalation are provided, wherein said compositions additionally comprise particles of at least one additional active agent. Also provided are methods of preparation of the compositions and their use in medicine.
    Type: Application
    Filed: January 29, 2014
    Publication date: December 24, 2015
    Applicant: Prosonix Limited
    Inventors: John Burns, Dipesh Parikh
  • Publication number: 20150352077
    Abstract: Pharmaceutical Preparations Multi-component crystalline particles and compositions, methods for their preparation, their uses in inhalation therapy and inhaler devices containing said particles are provided, in particular particles comprising glycopyrrolate. The particles can be prepared substantially free of excipients and agents other than active agents or their precursors in the presence of ultrasonic irradiation in a process comprising contacting a solution in a first flowing stream with an anti-solvent in a re-circulating second flowing stream, causing the mixing thereof and collecting crystals that are generated.
    Type: Application
    Filed: January 29, 2014
    Publication date: December 10, 2015
    Applicant: Prosonix Limited
    Inventors: John Burns, Dipesh Parikh, Shyam Karki
  • Publication number: 20140228330
    Abstract: This invention provides a pharmaceutical composition comprising a eutectic composition of two pharmacologically active ingredients for delivery to the lung by inhalation. This invention also provides a pharmaceutical composition comprising a eutectic composition of two pharmacologically active ingredients for the treatment of respiratory disease.
    Type: Application
    Filed: August 8, 2012
    Publication date: August 14, 2014
    Inventors: Graham Ruecroft, Dipesh Parikh
  • Patent number: 8771744
    Abstract: The invention provides a process for increasing the crystallinity of at least one solid material which is less than 100% crystalline, comprising applying ultrasound to the substantially dry solid material.
    Type: Grant
    Filed: October 20, 2010
    Date of Patent: July 8, 2014
    Assignee: Prosonix Limited
    Inventors: Graham Ruecroft, Dipesh Parikh
  • Publication number: 20120309729
    Abstract: The invention provides a process for increasing the crystallinity of at least one solid material which is less than 100% crystalline, comprising applying ultrasound to the substantially dry solid material.
    Type: Application
    Filed: October 20, 2010
    Publication date: December 6, 2012
    Inventors: Graham Ruecroft, Dipesh Parikh
  • Publication number: 20110146678
    Abstract: This invention provides a process for increasing the crystallinity of at least one solid material which is less than 100% crystalline, comprising contacting said solid material with solvent in which the solid material is insoluble or poorly soluble (a non-solvent); and applying ultrasound to the solid material when in contact with said non-solvent.
    Type: Application
    Filed: July 20, 2009
    Publication date: June 23, 2011
    Inventors: Graham Ruecroft, Dipesh Parikh
  • Publication number: 20100269825
    Abstract: Crystalline particles wherein each particle comprises a combination of a pharmaceutically acceptable salt of 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]-2(1H)-quinolinone (carmoterol), and a corticosteroid in a pre-determined and constant ratio are effective for the prevention and treatment of inflammatory or obstructive airways diseases.
    Type: Application
    Filed: February 25, 2010
    Publication date: October 28, 2010
    Applicant: Chiesi Farmaceutici S.p.A.
    Inventors: Daniela COCCONI, Rossella MUSA, Gaetano BRAMBILLA, Dipesh PARIKH, Graham RUECROFT
  • Publication number: 20100190760
    Abstract: A process for preparing an emulsion or a dispersion comprising crystalline particles of at least one active principal that comprises contacting a solution of at least one solute in a solvent or mixture of solvents in a first flowing stream with a non-solvent in a second flowing stream wherein the non-solvent and solvent are not miscible with each other, so as to form an emulsion or a dispersion. Super saturation is brought about by suitable means, and the emulsion or dispersion is subjected to ultrasonic irradiation to mediate crystal nucleation.
    Type: Application
    Filed: June 17, 2008
    Publication date: July 29, 2010
    Applicant: PROSONIX LIMITED
    Inventors: Graham Ruecroft, James Robinson, Dipesh Parikh