Patents by Inventor Dipti Thakkar

Dipti Thakkar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION FOR TREATMENT AND PREVENTION OF CANCER
    Publication number: 20260201061
    Abstract: The present disclosure provides methods for the treatment or prevention of cancers, comprising administration of antigen-binding molecules that bind to HER3 and antigen-binding molecules that bind to EGFR. Also provided are pharmaceutical combinations comprising said molecules, and therapeutic and prophylactic methods of using said pharmaceutical combinations.
    Type: Application
    Filed: December 6, 2023
    Publication date: July 16, 2026
    Inventors: Piers Ingram, Jerome Boyd-kirup, Dipti Thakkar, Eric Rowinsky, Weiyi Toy
  • BCMA/TACI antigen-binding molecules
    Patent number: 12643952
    Abstract: BCMA/TACI antigen-binding molecules are disclosed. Also disclosed are nucleic acids and expression vectors encoding, compositions comprising, and methods using, the BCMA/TACI antigen-binding molecules.
    Type: Grant
    Filed: November 2, 2021
    Date of Patent: June 2, 2026
    Assignee: Hummingbird Bioscience Pte. Ltd.
    Inventors: Fabien Decaillot, Jerome Douglas Boyd-Kirkup, Dipti Thakkar, Piers Ingram, Konrad Paszkiewicz, Chia-Yi Liu
  • TREATMENT AND PREVENTION OF CANCER USING HER3 ANTIGEN-BINDING MOLECULES
    Publication number: 20260132219
    Abstract: Methods for treating or preventing a cancer in a subject are disclosed, wherein the cancer comprises cells having a mutation resulting in increased expression of a ligand for HER3, wherein the method comprises administering a therapeutically or prophylactically effective amount of an antigen-binding molecule which is capable of binding to HER3 to the subject.
    Type: Application
    Filed: August 15, 2025
    Publication date: May 14, 2026
    Applicant: Hummingbird Bioscience Pte. Ltd.
    Inventors: Jerome Boyd-Kirkup, Siyu Guan, Piers Ingram, Konrad Paszkiewicz, Vicente Sancenon, Dipti Thakkar, Zhihao Wu
  • TREATMENT AND PREVENTION OF CANCER USING VISTA ANTIGEN-BINDING MOLECULES
    Publication number: 20260098093
    Abstract: VISTA antigen-binding molecules are disclosed. Also disclosed are nucleic acids and expression vectors encoding, composition comprising, and methods using, the VISTA antigen-binding molecules.
    Type: Application
    Filed: September 21, 2023
    Publication date: April 9, 2026
    Inventors: Bhushan Dharmadhikari, Olga Zharkova, Debleena Ray, Roberto Tirado-Magallanes, Dipti Thakkar, Konrad Paszkiewicz, Jerome Boyd-Kirkup, Piers Ingram
  • TREATMENT AND PREVENTION OF CANCER USING VISTA ANTIGEN-BINDING MOLECULES
    Publication number: 20250313631
    Abstract: The present disclosure provides antigen-binding molecules that bind to VISTA for the treatment or prevention of cancers, compositions comprising said molecules, and therapeutic and prophylactic methods using said molecules.
    Type: Application
    Filed: September 16, 2022
    Publication date: October 9, 2025
    Applicant: Hummingbird Bioscience Pte. Ltd.
    Inventors: Jerome Boyd-Kirkup, Siyu Guan, Konrad Paszkiewicz, Eric Rowinsky, Dipti Thakkar, Bhushan Dharmadhikari, Piers Ingram
  • TREATMENT AND PREVENTION OF CANCER USING HER3 ANTIGEN-BINDING MOLECULES
    Publication number: 20250136712
    Abstract: The present disclosure provides the use of an antigen-binding molecule that binds to HERS for the treatment or prevention of cancers comprising (i) at least one gene encoding a positive regulator of HERS-mediated signalling that does not comprise an activating mutation; or (ii) at least one gene encoding a negative regulator of HERS-mediated signalling that does not comprise an inactivating mutation.
    Type: Application
    Filed: August 12, 2022
    Publication date: May 1, 2025
    Applicant: Hummingbird Bioscience Pte. Ltd.
    Inventors: Jerome Douglas Boyd-Kirkup, Shreya kar, Konrad Paszkiewicz, Dipti Thakkar, Piers Ingram
  • TREATMENT AND PREVENTION OF CANCER USING HER3 ANTIGEN-BINDING MOLECULES
    Publication number: 20250122303
    Abstract: The present disclosure provides antigen-binding molecules that bind to HER3 for the treatment or prevention of cancers, compositions comprising said molecules, and therapeutic and prophylactic methods using said molecules.
    Type: Application
    Filed: September 2, 2022
    Publication date: April 17, 2025
    Inventors: Nigel Westwood, Harriet Walters, Gavin Halbert, Jennifer L. Craigen, Siyu Guan, Jerome Boyd-Kirkup, Piers Ingram, Dipti Thakkar
  • HER3 ANTIGEN-BINDING MOLECULES
    Publication number: 20250019461
    Abstract: HER3 antigen-binding molecules are disclosed. Also disclosed are nucleic acids and expression vectors encoding, compositions comprising, and methods using, the HER3 antigen-binding molecules.
    Type: Application
    Filed: September 16, 2024
    Publication date: January 16, 2025
    Applicant: Hummingbird Bioscience Pte. Ltd.
    Inventors: Jerome Douglas Boyd-Kirkup, Piers Ingram, Dipti Thakkar, Zhihao Wu, Konrad Paszkiewicz, Vicente Sancenon, Siyu Guan
  • CELLS EXPRESSING VISTA ANTIGEN-BINDING MOLECULES
    Publication number: 20240279340
    Abstract: Cells expressing VISTA antigen-binding molecules are disclosed. Also disclosed are compositions comprising such cells, methods for producing VISTA antigen-binding molecules using such cells, and compositions comprising and methods using the VISTA antigen-binding molecules expressed by such cells.
    Type: Application
    Filed: June 13, 2022
    Publication date: August 22, 2024
    Inventors: Jerome Douglas Boyd-Kirkup, Piers Ingram, Dipti Thakkar, Siyu Guan, Akila Sadasivam
  • CELLS EXPRESSING HER3 ANTIGEN-BINDING MOLECULES
    Publication number: 20240270871
    Abstract: Cells expressing HER3 antigen-binding molecules are disclosed. Also disclosed are compositions comprising such cells, methods for producing HER3 antigen-binding molecules using such cells, and compositions comprising and methods using the HER3 antigen-binding molecules expressed by such cells.
    Type: Application
    Filed: June 13, 2022
    Publication date: August 15, 2024
    Inventors: Jerome Douglas Boyd-Kirkup, Piers Ingram, Dipti Thakkar, Siyu Guan, Akila Sadasivam
  • HER3-BINDING ANTIBODY-DRUG CONJUGATE
    Publication number: 20240238439
    Abstract: Methods of treating cancer are provided, as well as compositions including an antigen-binding molecule that binds to HER3, comprising (i) a HER3-binding moiety, and (ii) a linker-payload moiety comprising exatecan or a derivative thereof.
    Type: Application
    Filed: January 3, 2024
    Publication date: July 18, 2024
    Inventors: Suhail Ahmed Kabeer Rasheed, Dipti Thakkar, Shalini Paliwal, Wen Jie Chin, Akshaya Bansal, Benjamin Ayers, Cheng Theng Ng, Brendon Hanson, Piers Ingram, Jerome Boyd-Kirkup
  • VISTA ANTIGEN-BINDING MOLECULES
    Publication number: 20240158538
    Abstract: VISTA antigen-binding molecules are disclosed. Also disclosed are nucleic acids and expression vectors encoding, compositions comprising, and methods using, the VISTA antigen-binding molecules.
    Type: Application
    Filed: November 22, 2023
    Publication date: May 16, 2024
    Applicant: Hummingbird Bioscience Pte. Ltd.
    Inventors: Jerome Boyd-Kirkup, Piers Ingram, Dipti Thakkar, Zhihao Wu, Konrad Paszkiewicz, Vicente Sancenon, Siyu Guan
  • HER3 ANTIGEN-BINDING MOLECULES
    Publication number: 20240092937
    Abstract: HER3 antigen-binding molecules are disclosed. Also disclosed are nucleic acids and expression vectors encoding, compositions comprising, and methods using, the HER3 antigen-binding molecules.
    Type: Application
    Filed: August 30, 2023
    Publication date: March 21, 2024
    Applicant: Hummingbird Bioscience Pte. Ltd.
    Inventors: Jerome Douglas Boyd-Kirkup, Piers Ingram, Dipti Thakkar, Zhihao Wu, Konrad Paszkiewicz, Vicente Sancenon, Siyu Guan
  • VISTA antigen-binding molecules
    Patent number: 11873346
    Abstract: VISTA antigen-binding molecules are disclosed. Also disclosed are nucleic acids and expression vectors encoding, compositions comprising, and methods using, the VISTA antigen-binding molecules.
    Type: Grant
    Filed: March 18, 2020
    Date of Patent: January 16, 2024
    Assignee: Hummingbird Bioscience Pte. Ltd.
    Inventors: Jerome Douglas Boyd-Kirkup, Piers Ingram, Dipti Thakkar, Zhihao Wu, Konrad Paszkiewicz, Vicente Sancenon, Siyu Guan
  • BCMA/TACI ANTIGEN-BINDING MOLECULES
    Publication number: 20230374147
    Abstract: BCMA/TACI antigen-binding molecules are disclosed. Also disclosed are nucleic acids and expression vectors encoding, compositions comprising, and methods using, the BCMA/TACI antigen-binding molecules.
    Type: Application
    Filed: November 2, 2021
    Publication date: November 23, 2023
    Inventors: Fabien Decaillot, Jerome Douglas Boyd-Kirkup, Dipti Thakkar, Piers Ingram, Konrad Paszkiewicz, Chia-Yi Liu
  • HER3 antigen-binding molecules
    Patent number: 11780933
    Abstract: HER3 antigen-binding molecules are disclosed. Also disclosed are nucleic acids and expression vectors encoding, compositions comprising, and methods using, the HER3 antigen-binding molecules.
    Type: Grant
    Filed: February 28, 2020
    Date of Patent: October 10, 2023
    Assignee: Hummingbird Bioscience Pte. Ltd.
    Inventors: Jerome Douglas Boyd-Kirkup, Piers Ingram, Dipti Thakkar, Zhihao Wu, Konrad Paszkiewicz, Vicente Sancenon, Siyu Guan
  • CD47 antigen-binding molecules
    Patent number: 11685789
    Abstract: CD47 antigen-binding molecules are disclosed. Also disclosed are nucleic acids and expression vectors encoding, compositions comprising, and methods using, the CD47 antigen-binding molecules.
    Type: Grant
    Filed: June 22, 2022
    Date of Patent: June 27, 2023
    Assignee: Hummingbird Bioscience Pte. Ltd.
    Inventors: Jerome Boyd-Kirkup, Dipti Thakkar, Piers Ingram, Zhihao Wu, Konrad Paszkiewicz, Peter Brauer, Siyu Guan
  • CD47 ANTIGEN-BINDING MOLECULES
    Publication number: 20220356250
    Abstract: CD47 antigen-binding molecules are disclosed. Also disclosed are nucleic acids and expression vectors encoding, compositions comprising, and methods using, the CD47 antigen-binding molecules.
    Type: Application
    Filed: June 22, 2022
    Publication date: November 10, 2022
    Applicant: Hummingbird Bioscience Holdings Pte. Ltd.
    Inventors: Jerome Douglas Boyd-Kirkup, Dipti Thakkar, Piers Ingram, Zhihao Wu, Konrad Paszkiewicz, Peter Brauer, Siyu Guan
  • CD47 ANTIGEN-BINDING MOLECULES
    Publication number: 20220298254
    Abstract: CD47 antigen-binding molecules are disclosed. Also disclosed are nucleic acids and expression vectors encoding, compositions comprising, and methods using, the CD47 antigen-binding molecules.
    Type: Application
    Filed: November 1, 2018
    Publication date: September 22, 2022
    Applicant: Hummingbird Bioscience Holdings Pte. Ltd.
    Inventors: Jerome Douglas Boyd-Kirkup, Dipti Thakkar, Piers Ingram, Zhihao Wu, Konrad Paszkiewicz, Peter Brauer, Siyu Guan
  • TREATMENT AND PREVENTION OF CANCER USING HER3 ANTIGEN-BINDING MOLECULES
    Publication number: 20220153870
    Abstract: Methods for treating or preventing a cancer in a subject are disclosed, wherein the cancer comprises cells having a mutation resulting in increased expression of a ligand for HER3, wherein the method comprises administering a therapeutically or prophylactically effective amount of an antigen-binding molecule which is capable of binding to HER3 to the subject.
    Type: Application
    Filed: November 24, 2021
    Publication date: May 19, 2022
    Applicant: Hummingbird Biosciences Holdings Limited
    Inventors: Jerome Douglas Boyd-Kirkup, Siyu Guan, Piers Ingram, Konrad Paszkiewicz, Vicente Sancenon, Dipti Thakkar, Zhihao Wu