Patents by Inventor Dirgha Raj JOSHI

Dirgha Raj JOSHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • (2E,4E)-5-PHENYL-PENTA-2,4-DIEN-1-ONE DERIVATIVE
    Publication number: 20200157048
    Abstract: The present application relates to a novel pentadienoyl compound and a pharmaceutical composition including the same. The pentadienoyl compound of the present application may be used to prevent or treat fatty liver and fatty liver-related disease by inhibiting lipogenesis and lipid accumulation in cells and activating lipid metabolism. In addition, the pentadienoyl compound of the present application may increase a SIRT1 expression level in cells or SIRT1 activity, and thus may be used to prevent or treat a SIRT1-mediated disease. In addition, the pentadienoyl compound of the present application may reduce a CK2 expression level in cells or CK2 activity, and thus may be used to prevent or treat a CK2-mediated disease.
    Type: Application
    Filed: March 26, 2019
    Publication date: May 21, 2020
    Inventors: Jong Woo KIM, Chi Woo LEE, Hak Sung KIM, Dirgha Raj JOSHI, Sang Hoon KWON