Patents by Inventor Dirk André Emmy Roymans

Dirk André Emmy Roymans has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RSV ANTIVIRAL PYRAZOLO- AND TRIAZOLO-PYRIMIDINE COMPOUNDS
    Publication number: 20180105529
    Abstract: The invention concerns novel substituted pyrazolo- and triazolo-pyrimidine compounds of formula (I) having antiviral activity, in particular, having an inhibitory activity on the replication of the respiratory syncytial virus (RSV). The invention further concerns pharmaceutical compositions comprising these compounds and the compounds for use in the treatment of respiratory syncytial virus infection.
    Type: Application
    Filed: April 27, 2016
    Publication date: April 19, 2018
    Applicant: Janssen Sciences Ireland UC
    Inventors: David Francis Alain LANÇOIS, Jérôme Émile Georges GUILLEMONT, Pierre Jean-Marie Bernard RABOISSON, Dirk André Emmy ROYMANS, Boris ROGOVOY, Vadim BICHKO, Delphine Yvonne Raymonde LARDEAU, Antoine Benjamin MICHAUT, Anil KOUL
  • SUBSTITUTED PYRIDINE-PIPERAZINYL ANALOGUES AS RSV ANTIVIRAL COMPOUNDS
    Publication number: 20170291891
    Abstract: The invention concerns novel substituted pyridine-piperazinyl analogues of formula (I) having antiviral activity, in particular, having an inhibitory activity on the replication of the respiratory syncytial virus (RSV). The invention further concerns the preparation of such novel compounds, compositions comprising these compounds, and the compounds for use in the treatment of respiratory syncytial virus infection.
    Type: Application
    Filed: June 23, 2017
    Publication date: October 12, 2017
    Inventors: Jerôme Emile Georges GUILLEMONT, David Francis Alain LANÇOIS, Magali Madeleine Simone MOTTE, Delphine Yvonne Raymonde LARDEAU, Xavier Marc BOURDREZ, Wendy Mia Albert BALEMANS, Dirk André Emmy ROYMANS
  • SUBSTITUTED PYRIDINE-PIPERAZINYL ANALOGUES AS RSV ANTIVIRAL COMPOUNDS
    Publication number: 20160168124
    Abstract: The invention concerns novel substituted pyridine-piperazinyl analogues of formula (I) having antiviral activity, in particular, having an inhibitory activity on the replication of the respiratory syncytial virus (RSV). The invention further concerns the preparation of such novel compounds, compositions comprising these compounds, and the compounds for use in the treatment of respiratory syncytial virus infection.
    Type: Application
    Filed: July 29, 2014
    Publication date: June 16, 2016
    Applicant: JANSSEN SCIENCES IRELAND UC
    Inventors: Jerôme Emile Georges GUILLEMONT, David Francis Alain LANÇOIS, Magali Madeleine Sirnone MOTTE, Delohine Yvonne Raymonde LARDEAU, Xavier MARC BOURDREZ, Wendy Mia Albert BALEMANS, Dirk André Emmy ROYMANS
  • POTENTIOMETRIC SENSOR
    Publication number: 20150226695
    Abstract: The invention relates to a flux based ion selective electrode sensing device for biological molecules or substances. The device comprises an ion selective sensor, an incorporated passive flux of the ion and biological recognition element. The device measures the change in flux away from the sensor of the ion fluxing out of the sensor upon binding of the analyte on the sensor surface by means of the biological recognition element.
    Type: Application
    Filed: September 13, 2013
    Publication date: August 13, 2015
    Inventors: Eric Bakker, Hugo Achiel J. Bohets, Kristien Simonne Raymonda Bonroy, Marcin Milosz Marczak, Mahir Sinan Özdemir, Dirk Andre Emmy Roymans, Koen Jeroom Vanhoutte
  • Methods for identifying inhibitors against viruses that use a class I fusion protein
    Patent number: 8898047
    Abstract: The invention concerns the generation of a three dimensional model of the six helix bundle (6HB) complexed with an inhibitor and the use of that model to identify, screen and/or develop inhibitors against viruses that use a class I fusion protein. Such inhibitors of viruses that use a class I fusion protein may be effective for treating, for example, respiratory infections by Respiratory Syncytial Virus (RSV).
    Type: Grant
    Filed: February 26, 2009
    Date of Patent: November 25, 2014
    Assignee: Janssen Pharmaceuticals NV
    Inventors: Dirk André Emmy Roymans, Hendrik Leon Augusta Jozef De Bondt, Eric Pierre Alexandre Arnoult, Herman Van Vlijmen, Jean-François Bonfanti
  • METHODS FOR IDENTIFIYING INHIBITORS AGAINST VIRUSES THAT USE A CLASS I FUSION PROTEIN
    Publication number: 20110009408
    Abstract: The invention concerns the generation of a three dimensional model of the six helix bundle (6HB) complexed with an inhibitor and the use of that model to identify, screen and/or develop inhibitors against viruses that use a class I fusion protein. Such inhibitors of viruses that use a class I fusion protein may be effective for treating, for example, respiratory infections by Respiratory Syncytial Virus (RSV).
    Type: Application
    Filed: February 26, 2009
    Publication date: January 13, 2011
    Inventors: Dirk André Emmy Roymans, Hendrik Leon Augusta Jozef De Bondt, Eric Pierre Alexandre Arnoult, Herman Van Vlijmen, Jean-François Bonfanti