Patents by Inventor Dirk E. Smith

Dirk E. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7250276
    Abstract: The invention is directed to purified and isolated novel human IL-1 epsilon polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, the use of such polypeptides and fragmented peptides in cellular and immune reactions and as molecular weight markers, the use of such polypeptides and fragmented peptides as controls for peptide fragmentation, and kits comprising these reagents.
    Type: Grant
    Filed: November 12, 2004
    Date of Patent: July 31, 2007
    Assignee: Immunex Corporation
    Inventors: John E Sims, Dirk E Smith
  • Patent number: 7217540
    Abstract: The invention is directed to novel, purified and isolated IL-1 zeta and Xrec2 polypeptides and fragments thereof, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, and uses thereof.
    Type: Grant
    Filed: July 9, 2004
    Date of Patent: May 15, 2007
    Assignee: Immunex Corporation
    Inventors: John E. Sims, Dirk E. Smith, Teresa L. Born
  • Patent number: 7049095
    Abstract: DNA encoding IL-1R AcP splice variant polypeptides, the polypeptides and methods for using the encoded polypeptides are disclosed.
    Type: Grant
    Filed: October 26, 2001
    Date of Patent: May 23, 2006
    Assignee: Immunex Corporation
    Inventors: John E. Sims, Dirk E. Smith
  • Patent number: 7033783
    Abstract: The invention is directed to novel, purified and isolated IL-1 zeta and Xrec2 polypeptides and fragments thereof, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, and uses thereof.
    Type: Grant
    Filed: June 6, 2001
    Date of Patent: April 25, 2006
    Assignee: Immunex Corp.
    Inventors: John E. Sims, Dirk E. Smith, Teresa L. Born
  • Patent number: 6949359
    Abstract: The invention is directed to purified and isolated novel human IL-1 epsilon polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, the use of such polypeptides and fragmented peptides in cellular and immune reactions and as molecular weight markers, the use of such polypeptides and fragmented peptides as controls for peptide fragmentation, and kits comprising these reagents.
    Type: Grant
    Filed: August 20, 1999
    Date of Patent: September 27, 2005
    Assignee: Immunex Corporation
    Inventors: John E. Sims, Dirk E. Smith
  • Patent number: 6838290
    Abstract: The invention is directed to purified and isolated novel human IL-1 epsilon polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, the use of such polypeptides in cellular and immune reactions, the use of such polypeptides in screening for agonists or antagonists of IL-1 epsilon activity, and kits comprising such polypeptides.
    Type: Grant
    Filed: October 2, 2001
    Date of Patent: January 4, 2005
    Assignee: Immunex Corporation
    Inventors: John E. Sims, Dirk E. Smith
  • Publication number: 20040248187
    Abstract: The invention is directed to novel, purified and isolated IL-1 zeta and Xrec2 polypeptides and fragments thereof, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, and uses thereof.
    Type: Application
    Filed: July 9, 2004
    Publication date: December 9, 2004
    Applicant: Immunex Corporation
    Inventors: John E. Sims, Dirk E. Smith, Teresa L. Born
  • Publication number: 20030170632
    Abstract: DNA encoding IL-1R AcP splice variant polypeptides, the polypeptides and methods for using the encoded polypeptides are disclosed.
    Type: Application
    Filed: October 26, 2001
    Publication date: September 11, 2003
    Inventors: John E. Sims, Dirk E. Smith
  • Publication number: 20030091532
    Abstract: The invention is directed to novel, purified and isolated IL-1 zeta and Xrec2 polypeptides and fragments thereof, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, and uses thereof.
    Type: Application
    Filed: June 6, 2001
    Publication date: May 15, 2003
    Inventors: John E. Sims, Dirk E. Smith, Teresa L. Born
  • Publication number: 20030049255
    Abstract: The invention pertains to methods for treating medical disorders characterized by elevated levels or abnormal expression of IL-1 by administering an IL-1 antagonist, such as soluble type II IL-1 receptor and/or IL-1RAcP.
    Type: Application
    Filed: August 7, 2002
    Publication date: March 13, 2003
    Inventors: John E. Sims, Dirk E. Smith
  • Publication number: 20020155506
    Abstract: The invention is directed to purified and isolated novel human IL-1 epsilon polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, the use of such polypeptides in cellular and immune reactions, the use of such polypeptides in screening for agonists or antagonists of IL-1 epsilon activity, and kits comprising such polypeptides.
    Type: Application
    Filed: October 2, 2001
    Publication date: October 24, 2002
    Inventors: John E. Sims, Dirk E. Smith
  • Patent number: 5848394
    Abstract: An automated system and method for producing a work breakdown structure for a project, such as a software development project. The resulting work breakdown structure provides a common framework for communicating cost, scope and schedule information relating to the project. The system includes a function point component list which identifies the files and tables which represent the product to be developed for the project or projects. The function point component list also contains information about the elementary transactions by which each file or table is modified or maintained. The system further includes a work breakdown structure template file, in which a list of identifiable tasks and resources required to accomplish a project is maintained. Using the function point component list and the work breakdown structure template file, the system generates an electronic work breakdown structure output file in which information about the total work required to accomplish the objectives of a project is stored.
    Type: Grant
    Filed: September 18, 1996
    Date of Patent: December 8, 1998
    Assignee: Leonard & Caroline White
    Inventors: Christopher S. D'Arrigo, Dirk E. Smith