Patents by Inventor Dirk Fabritius

Dirk Fabritius has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230212616
    Abstract: The present invention relates to a method for the stereo selective production of a trans-diol or a cis-diol or a hydroxyketone comprising the step(s) (i) conversion of a trans-diol or a cis-diol to a hydroxyketone and/or (ii) conversion of a hydroxyketone to a cis-diol or a trans-diol, catalyzed by an enzyme, which is encoded by a nucleic acid sequence of SEQ ID NO: or wherein the enzyme comprises an amino acid sequence of SEQ ID NO: 2. The present invention also relates to the use of an enzyme encoded by a nucleic acid sequence of SEQ ID NO: 1 or wherein the enzyme comprises an amino acid sequence of SEQ ID NO: 2 for the conversion of a trans-diol to a cis-diol or for the conversion of a trans-diol or a cis-diol to a hydroxyketone and/or the conversion of a hydroxyketone to a trans-diol or a cis-diol.
    Type: Application
    Filed: July 8, 2019
    Publication date: July 6, 2023
    Inventors: Dirk FABRITIUS, Stefan LAMBRECHT, Johannes PANTEN, Marcus EH
  • Publication number: 20090275658
    Abstract: The invention relates to a method for producing a raw oil from micro-organisms and plants, oil produced according to said method and specific uses of the thus produced oil and, optionally, additional refined oil in foodstuffs, in food supplements, or in cosmetic or pharmaceutical compositions.
    Type: Application
    Filed: December 20, 2005
    Publication date: November 5, 2009
    Inventor: Dirk Fabritius
  • Patent number: 7588791
    Abstract: A process for increasing the concentration of PUFA triglycerides present in natural PUFA oils, in which a natural PUFA oil having a triglyceride content of more than 85% by weight, based on the total weight of the mixture, and having a total PUFA content of more than 39% by weight of total fatty acids is dissolved in an organic solvent or an organic solvent mixture, the mixture is allowed to stand at a temperature of from ?35° C. to ?100° C. for a period of more than five minutes, the mixture is separated into a supernatant comprising PUFA-triglyceride mixture and a sediment phase, the separation preferably taking place by filtration or centrifugation, and the solvent or solvent mixture, after the removal of the sediment phase, is separated from the supernatant.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: September 15, 2009
    Assignee: Nutrinova Nutrition Specialties & Food Ingredients GmbH
    Inventor: Dirk Fabritius
  • Patent number: 7476522
    Abstract: The invention relates to a method for the fermentative production of lipids/fatty acids having high concentrations of omega-6 fatty acids (PUFA, polyunsaturated fatty acids), especially ?-linolenic acids (GLA) in ciliates. Said lipids/fatty acids can be used in human/animal food, and in the pharmaceutical field.
    Type: Grant
    Filed: May 18, 2006
    Date of Patent: January 13, 2009
    Assignee: Nutrinova Nutrition Specialties & Food Ingredients GmbH
    Inventors: Anton Van V. Putten, Tanja König, Dirk Fabritius, Thomas Kiy, Alexander Leske, Joern Plote
  • Publication number: 20080206379
    Abstract: The invention relates to an antioxidant extract from Crypthecodinium sp. The invention also relates to a fatty acid composition which comprises at least one unsaturated fatty acid and/or at least one unsaturated fatty acid ester and at least one extract according to the invention and constituents of a biomass different from Crypthecodinium sp., to a method for producing the fatty acid composition and to its use.
    Type: Application
    Filed: January 26, 2006
    Publication date: August 28, 2008
    Inventors: Dirk Fabritius, Doreen Neumann
  • Publication number: 20080175975
    Abstract: The invention relates to a method for producing a fatty acid composition which, based on the entire weight of the fatty acids and/or fatty acid derivatives contained in the fatty acid composition, contains at least 70.0% by weight of docosahexaenoic acid and/or docosahexaenoic alkyl ester. The inventive method comprises the following steps: a) transesterifying a biomass obtained from Ulkenia sp. with an alcohol, thereby producing at least one docosahexaenoic alkyl ester and at least one saturated fatty acid ester, b) producing a solution which contains urea, at least a part of the biomass from step a) and at least one organic solvent, c) cooling or concentrating the solution from step b), thereby producing i) a precipitate which contains urea and at least a part of the saturated fatty acid esters, and ii) a liquid fraction, and d) separating the precipitate i) from the liquid fraction ii).
    Type: Application
    Filed: January 26, 2006
    Publication date: July 24, 2008
    Applicant: NUTRINOVA NUTRITION SPECIALTIES & FOOD INGREDIENTS GMBH
    Inventor: Dirk Fabritius
  • Patent number: 7368603
    Abstract: The present invention relates to a method for producing a saturated organic compound bearing at least one functional group from a mixture which comprises this saturated organic compound containing at least one functional group and also one or more other organic compounds, which comprises i) mixing a silver-ion-loaded ion exchanger with the mixture at a temperature which is below the boiling point of the mixture, ii) then removing the supernatant and iii) detaching the ion-exchanger-bound, saturated organic compound having at least one functional group from the ion exchanger.
    Type: Grant
    Filed: March 23, 2004
    Date of Patent: May 6, 2008
    Assignee: Lonza Ltd
    Inventors: Dirk Fabritius, Doreen Neumann
  • Patent number: 7365219
    Abstract: The invention relates to a novel extraction method for obtaining at least one unsaturated, optionally derivatized compound, from mixtures of said compounds with other less saturated constituents, e.g. for obtaining polyunsaturated fatty acids or the derivatives thereof from mixtures with saturated and/or less unsaturated, optionally derivatized fatty acids, by means of selective complexation with a cation exchanger which is partially or fully charged with silver ions, and subsequent decomplexation.
    Type: Grant
    Filed: June 5, 2002
    Date of Patent: April 29, 2008
    Assignee: Nutrinova Nutrition Specialties & Food Indredients GmbH
    Inventors: Dirk Fabritius, Silke Reimann, Doreen Neumann, Daniel Minoer
  • Publication number: 20060205047
    Abstract: The invention relates to a method for the fermentative production of lipids/fatty acids having high concentrations of omega-6 fatty acids (PUFA, polyunsaturated fatty acids), especially ?-linolenic acids (GLA) in ciliates. Said lipids/fatty acids can be used in human/animal food, and in the pharmaceutical field.
    Type: Application
    Filed: May 18, 2006
    Publication date: September 14, 2006
    Inventors: Anton V. Putten, Tanja Konig, Dirk Fabritius, Thomas Kiy, Alexander Leske, Joern Plote
  • Patent number: 7081356
    Abstract: The intention relates to a method for the fermentative production of lipids/fatty acids having high concentrations of omega-6 fatty acids (PUFA, polyunsaturated fatty acids), especially ?-linolenic acids (GLA) in ciliates. Said lipids/fatty acids can be used in human/animal food, and in the pharmaceutical field.
    Type: Grant
    Filed: February 8, 2002
    Date of Patent: July 25, 2006
    Assignee: Nutrinova Nutrition Specialities & Food Ingredients GmbH
    Inventors: Anton van V. Putten, Tanja König, Dirk Fabritius, Thomas Kiy, Alexander Leske, Joem Plote
  • Publication number: 20050129831
    Abstract: A process for increasing the concentration of PUFA triglycerides present in natural PUFA oils, in which a natural PUFA oil having a triglyceride content of more than 85% by weight, based on the total weight of the mixture, and having a total PUFA content of more than 39% by weight of total fatty acids is dissolved in an organic solvent or an organic solvent mixture, the mixture is allowed to stand at a temperature of from ?35° C. to ?100° C. for a period of more than five minutes, the mixture is separated into a supernatant comprising PUFA-triglyceride mixture and a sediment phase, the separation preferably taking place by filtration or centrifugation, and the solvent or solvent mixture, after the removal of the sediment phase, is separated from the supernatant.
    Type: Application
    Filed: October 16, 2002
    Publication date: June 16, 2005
    Inventor: Dirk Fabritius
  • Publication number: 20040192967
    Abstract: The present invention relates to a method for producing a saturated organic compound bearing at least one functional group from a mixture which comprises this saturated organic compound containing at least one functional group and also one or more other organic compounds, which comprises
    Type: Application
    Filed: March 23, 2004
    Publication date: September 30, 2004
    Inventors: Dirk Fabritius, Doreen Neumann
  • Publication number: 20040180414
    Abstract: The intention relates to a method for the fermentative production of lipids/fatty acids having high concentrations of omega-6 fatty acids (PUFA, polyunsaturated fatty acids), especially &ggr;-linolenic acids (GLA) in ciliates. Said lipids/fatty acids can be used in human/animal food, and in the pharmaceutical field.
    Type: Application
    Filed: May 13, 2004
    Publication date: September 16, 2004
    Inventors: Anton van V Putten, Tanja Konig, Dirk Fabritius, Thomas Kiy, Alexander Leske, Joern Plote
  • Publication number: 20040162437
    Abstract: The invention relates to a novel extraction method for obtaining at least one unsaturated, optionally derivatised compound, from mixtures of said compounds with other less saturated constituents, e.g. for obtaining polyunsaturated fatty acids or the derivatives thereof from mixtures with saturated and/or less unsaturated, optionally derivatised fatty acids, by means of selective complexation with a cation exchanger which is partially or fully charged with silver ions, and subsequent decomplexation.
    Type: Application
    Filed: December 4, 2003
    Publication date: August 19, 2004
    Inventors: Dirk Fabritius, Silke Reimann, Doreen Neumann, Daniel Minor
  • Publication number: 20040048829
    Abstract: Molecular inclusion compounds consisting of at least (a) one linear, water-soluble polysaccharide and (b) one or more fatty acid or fatty acid derivative are disclosed. The polysaccharide may be obtained biocatalytically. Methods for manufacturing the molecular inclusion compounds and the use of the molecular inclusion compounds in pharmaceutical preparations, as an ingredient of functional foodstuffs in cosmetic preparations, and as food additives and supplements are also disclosed.
    Type: Application
    Filed: May 29, 2003
    Publication date: March 11, 2004
    Inventors: Stephan Hausmanns, Thomas Kiy, Dirk Fabritius, Ivan Tomka
  • Patent number: 6350890
    Abstract: The invention relates to a method for obtaining fatty acid esters and fatty acids, preferably unsaturated fatty acid ethyl esters, from biological sources by continuous, combined in-situ extraction, reaction and chromatography. The invention is characterized in that simultaneously and in the same location, in the presence of a compressed gas and an 0.5-5 % stream of lower alcohols as modifiers and in the presence of an inert catalyst, the fatty acids are fully transesterified from their native fatty acid sources, which are selectively desorbed and eluated in the conditions specified above.
    Type: Grant
    Filed: February 16, 2001
    Date of Patent: February 26, 2002
    Assignee: AXIVA GmbH
    Inventors: Thomas Kiy, Christoph Siffrin, Heinz Engelhardt, Dirk Fabritius