Patents by Inventor Dirk G. Meuleman

Dirk G. Meuleman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5164377
    Abstract: The present invention relates to sulphated glycosamino glycuronan with antithrombotic activity consisting essentially of salts of dermatan sulphate, chondroitin sulphate and heparan sulphate, characterized bya) an average molecular weight between 4000 and 8000 daltons;b) a nitrogen content between 2.4 and 3.0%;c) a sulphur content between 7.5 and 9.5%;d) a sodium content between 9 and 11%;e) a dermatan sulphate content between 5 and 25%;f) a chondroitin sulphate content less than 9%;g) an anti-Xa activity between 11 and 20 .mu./mg; andh) an antithrombin III dependent antithrombin activity of less than 1 .mu./mg.
    Type: Grant
    Filed: October 3, 1990
    Date of Patent: November 17, 1992
    Assignee: Akzo N.V.
    Inventors: Gijsbert W. K. Van Dedem, Francois E. A. Van Hou Denhoven, Dirk G. Meuleman, Huibert C. T. Moelker, Adrianus L. M. Sanders
  • Patent number: 4438108
    Abstract: A new anti-thromboticum based on a mixture of oligo- and polysaccharides is provided. The invention also relates to methods for preparation thereof and to pharmaceutical compositions including the said anti-thromboticum.The new product is of natural origin and can be obtained from mammal tissue, particularly intestinal mucous. The product is useful because of its high "benefit/risk" ratio (i.e. the ratio between the anti-thrombotic activity and the haemorrhagic activity).
    Type: Grant
    Filed: May 12, 1982
    Date of Patent: March 20, 1984
    Assignee: Akzo N.V.
    Inventors: Adrianus L. M. Sanders, Dirk G. Meuleman, Huibert C. T. Moelker, Gijsbert W. K. van Dedem, Francois E. A. van Houdenhoven