Patents by Inventor Dirk Goerlich

Dirk Goerlich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immobilisation of chelating groups for immobilised metal ion chromatography (IMAC)
    Patent number: 10538552
    Abstract: The present invention refers to a method for binding a polycarboxylic acid to a solid phase. Further, the invention refers to a solid phase having a polycarboxylic acid immobilized thereto and methods of using the solid phase, e.g. for purifying His-tagged recombinant polypeptides.
    Type: Grant
    Filed: April 19, 2017
    Date of Patent: January 21, 2020
    Assignee: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
    Inventors: Dirk Goerlich, Steffen Frey
  • Tag removal from proteins expressed in pro- and eukaryotic hosts
    Patent number: 10378003
    Abstract: The present invention belongs to the field of biotechnology. More specifically, the present invention provides a protease, a non-naturally occurring fusion protein comprising a corresponding protease recognition site, expression vectors encoding same, host cells comprising said expression vectors, kit of parts as well as methods applying the protease, fusion protein, and uses thereof, as defined in the claims. The presently disclosed protease/protease recognition site is particularly useful in methods requiring an orthogonal set of proteases, and is suitable for use in both prokaryotic and selected eukaryotic expression systems.
    Type: Grant
    Filed: November 10, 2015
    Date of Patent: August 13, 2019
    Assignee: MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.
    Inventors: Steffen Frey, Dirk Goerlich
  • TAG REMOVAL FROM PROTEINS EXPRESSED IN PRO- AND EUKARYOTIC HOSTS
    Publication number: 20180195056
    Abstract: The present invention belongs to the field of biotechnology. More specifically, the present invention provides a protease, a non-naturally occurring fusion protein comprising a corresponding protease recognition site, expression vectors encoding same, host cells comprising said expression vectors, kit of parts as well as methods applying the protease, fusion protein, and uses thereof, as defined in the claims.
    Type: Application
    Filed: November 10, 2015
    Publication date: July 12, 2018
    Applicant: MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.
    Inventors: Steffen FREY, Dirk GOERLICH
  • Immobilisation of Chelating Groups for Immobilised Metal Ion Chromatography (IMAC)
    Publication number: 20170218013
    Abstract: The present invention refers to a method for binding a polycarboxylic acid to a solid phase. Further, the invention refers to a solid phase having a polycarboxylic acid immobilized thereto and methods of using the solid phase, e.g. for purifying His-tagged recombinant polypeptides.
    Type: Application
    Filed: April 19, 2017
    Publication date: August 3, 2017
    Applicant: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Dirk GOERLICH, Steffen FREY
  • Immobilization of chelating groups for immobilized metal ion chromatography (IMAC)
    Patent number: 9675960
    Abstract: The present invention refers to a method for binding a polycarboxylic acid to a solid phase. Further, the invention refers to a solid phase having a polycarboxylic acid immobilized thereto and methods of using the solid phase, e.g. for purifying His-tagged recombinant polypeptides.
    Type: Grant
    Filed: May 28, 2015
    Date of Patent: June 13, 2017
    Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Dirk Goerlich, Steffen Frey
  • IMMOBILISATION OF CHELATING GROUPS FOR IMMOBILISED METAL ION CHROMATOGRAPHY (IMAC)
    Publication number: 20150283536
    Abstract: The present invention refers to a method for binding a polycarboxylic acid to a solid phase. Further, the invention refers to a solid phase having a polycarboxylic acid immobilized thereto and methods of using the solid phase, e.g. for purifying His-tagged recombinant polypeptides.
    Type: Application
    Filed: May 28, 2015
    Publication date: October 8, 2015
    Applicant: Max-Planck-Gesellschaft zur Foerderung Der Wissenschaften e.V.
    Inventors: Dirk GOERLICH, Steffen FREY
  • Immobilization of chelating groups for immobilized metal ion chromatography (IMAC)
    Patent number: 9073971
    Abstract: The present invention refers to a method for binding a polycarboxylic acid to a solid phase. Further, the invention refers to a solid phase having a polycarboxylic acid immobilized thereto and methods of using the solid phase, e.g. for purifying His-tagged recombinant polypeptides.
    Type: Grant
    Filed: August 6, 2008
    Date of Patent: July 7, 2015
    Assignee: Max-Planck-Gesellschaft zur Foerderung Der Wissenschaften e.V.
    Inventors: Dirk Goerlich, Steffen Frey
  • IMMOBILISATION OF CHELATING GROUPS FOR IMMOBILISED METAL ION CHROMATOGRAPHY (IMAC)
    Publication number: 20110071274
    Abstract: The present invention refers to a method for binding a polycarboxylic acid to a solid phase. Further, the invention refers to a solid phase having a polycarboxylic acid immobilized thereto and methods of using the solid phase, e.g. for purifying His-tagged recombinant polypeptides.
    Type: Application
    Filed: August 6, 2008
    Publication date: March 24, 2011
    Applicant: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Dirk Goerlich, Steffen Frey