Patents by Inventor Dirk Grafahrend
Dirk Grafahrend has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200289716Abstract: A biocompatible composite material for complete or partial insertion into a human body includes at least one layer comprising an elastomeric material, and at least one textile fabric arranged on the at least one layer comprising the elastomeric material. The at least one textile fabric forms a surface of the biocompatible composite material. The at least one textile fabric includes bioresorbable fibers that are embedded at least partially in the at least one layer comprising the elastomeric material.Type: ApplicationFiled: October 26, 2018Publication date: September 17, 2020Inventors: Karl-Heinz Heffels, Denis Reibel, Dirk Grafahrend, Alexandra Kaul, Yosuke Kadomae, Guenter Germann
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Publication number: 20200289715Abstract: A biocompatible soft tissue implant for introduction into a human body includes at least one layer comprising an elastomeric material, and at least one textile fabric arranged on the at least one layer comprising the elastomeric material. The at least one textile fabric forms a surface of the biocompatible soft tissue implant. The at least one textile fabric includes bioresorbable fibers which are embedded at least partially in the at least one layer comprising the elastomeric material.Type: ApplicationFiled: October 26, 2018Publication date: September 17, 2020Inventors: Karl-Heinz Heffels, Denis Reibel, Dirk Grafahrend, Guenter Germann, Oliver Boegershausen
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Patent number: 10736985Abstract: A medical device in the form of a nonwoven wound dressing includes rotospun fibers including at least one synthetic and bioabsorbable polymer and at least one hydrophilic and/or tissue-adhesive polymer, and a method of producing the medical device including using rotospinning to produce fibers from a fiber raw material including at least one synthetic and bioabsorbable polymer and at least one hydrophilic and/or tissue-adhesive polymer.Type: GrantFiled: February 12, 2015Date of Patent: August 11, 2020Assignees: Aesculap AG, Carl Freudenberg KGInventors: Erich Odermatt, Rainer Bargon, Dirk Grafahrend, Daniel Neumüller, Denis Reibel
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Patent number: 10196759Abstract: A multi-component fiber includes a first component made of a first fiber raw material and a second component made of a second fiber raw material. The first and second components are combined by rotational spinning so as to form a fiber body.Type: GrantFiled: January 18, 2011Date of Patent: February 5, 2019Assignee: CARL FREUDENBERG KGInventors: Wiebke Schmitz, Dirk Grafahrend, Denis Reibel
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Publication number: 20180008743Abstract: The present invention is directed to novel non-woven fabrics containing growth and differentiation factor proteins. Said fabrics are specifically designed to accelerate tissue regeneration and wound healing processes of mammalian tissues. Furthermore, the invention provides wound dressings, pads or implants comprising the novel non-woven fabrics.Type: ApplicationFiled: September 6, 2017Publication date: January 11, 2018Applicants: BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWI CKLUNG VON PHARMAKA MBH, CARL FREUDENBERG KGInventors: Frank Plöger, Denis Reibel, Dirk Grafahrend, Daniel Neumüller
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Patent number: 9782511Abstract: The present invention is directed to novel non-woven fabrics containing growth and differentiation factor proteins. Said fabrics are specifically designed to accelerate tissue regeneration and wound healing processes of mammalian tissues. Furthermore, the invention provides wound dressings, pads or implants comprising the novel non-woven fabrics.Type: GrantFiled: January 15, 2016Date of Patent: October 10, 2017Assignees: Biopharm Gesellschaft Zur Biotechnologischen Entwicklung von Pharmaka MBH, Carl Freudenberg KGInventors: Frank Plöger, Denis Reibel, Dirk Grafahrend, Daniel Neumüller
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Publication number: 20170165394Abstract: A medical device in the form of a nonwoven wound dressing includes rotospun fibers including at least one synthetic and bioabsorbable polymer and at least one hydrophilic and/or tissue-adhesive polymer, and a method of producing the medical device including using rotospinning to produce fibers from a fiber raw material including at least one synthetic and bioabsorbable polymer and at least one hydrophilic and/or tissue-adhesive polymer.Type: ApplicationFiled: February 12, 2015Publication date: June 15, 2017Inventors: Erich Odermatt, Rainer Bargon, Dirk Grafahrend, Daniel Neumüller, Denis Reibel
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Publication number: 20160199530Abstract: The present invention is directed to novel non-woven fabrics containing growth and differentiation factor proteins. Said fabrics are specifically designed to accelerate tissue regeneration and wound healing processes of mammalian tissues. Furthermore, the invention provides wound dressings, pads or implants comprising the novel non-woven fabrics.Type: ApplicationFiled: January 15, 2016Publication date: July 14, 2016Applicants: BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA MBH, CARL FREUDENBERG KGInventors: Frank Plöger, Denis Reibel, Dirk Grafahrend, Daniel Neumüller
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Patent number: 9278156Abstract: The present invention is directed to novel non-woven fabrics containing growth and differentiation factor proteins. Said fabrics are specifically designed to accelerate tissue regeneration and wound healing processes of mammalian tissues. Furthermore, the invention provides wound dressings, pads or implants comprising the novel non-woven fabrics.Type: GrantFiled: June 21, 2012Date of Patent: March 8, 2016Assignees: Biopharm Gesellschaft zur Biotechnologischen Entwicklung Von Pharmaka MBHInventors: Frank Plöger, Denis Reibel, Dirk Grafahrend, Daniel Neumüller
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Publication number: 20150010612Abstract: The invention relates to a biodegradable fleece containing (i) at least one polymer for inducing primary haemostasis, (ii) at least one non-proteinogenic, low-molecular, water-soluble activator of secondary haemostasis, and (iii) at least one non-proteinogenic, low-molecular, water-soluble inhibitor of fibrinolysis. The invention also relates to a method for producing a biodegradable fleece, in which (i) a fluidised fiber raw material, and additives if applicable, is placed in a container, (ii) the container is made to rotate, (iii) the fluidised fiber raw material is dispensed from the container by means of centrifugal forces, whereby fibers or filaments are formed, and (iv) a biodegradable fleece is produced from the fibers or filaments. The invention also relates to the use of said biodegradable fleece as a local haemostatic agent.Type: ApplicationFiled: January 23, 2013Publication date: January 8, 2015Applicants: CARL FREUDENBERG KG, HERAEUS MEDICAL GMBHInventors: Sebastian Vogt, Ekaterini Copanaki, Dirk Grafahrend, Denis Reibel, Daniel Neumüller
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Publication number: 20140141050Abstract: The present invention is directed to novel non-woven fabrics containing growth and differentiation factor proteins. Said fabrics are specifically designed to accelerate tissue regeneration and wound healing processes of mammalian tissues. Furthermore, the invention provides wound dressings, pads or implants comprising the novel non-woven fabrics.Type: ApplicationFiled: June 21, 2012Publication date: May 22, 2014Applicants: BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA MBH, CARL FREUDENBERG KGInventors: Frank Plöger, Denis Reibel, Dirk Grafahrend, Daniel Neumüller
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Publication number: 20130011676Abstract: A multi-component fiber includes a first component made of a first fiber raw material and a second component made of a second fiber raw material. The first and second components are combined by rotational spinning so as to firm a fiber body.Type: ApplicationFiled: January 18, 2011Publication date: January 10, 2013Applicant: CARL FREUDENBERG KGInventors: Wiebke Schmitz, Dirk Grafahrend, Denis Reibel
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Publication number: 20120150097Abstract: A medical instrument includes a tube, a bioresorbable nonwoven disposed in the tube, and a plunger disposed inside the tube that closes off a first end of the tube. The plunger is movable relative to the tube and slidable inside the tube so as to expel the nonwoven from the tube through actuation of the plunger.Type: ApplicationFiled: December 6, 2011Publication date: June 14, 2012Applicant: CARL FREUDENBERG KGInventors: Daniel Neumueller, Denis Reibel, Dirk Grafahrend