Patents by Inventor Dirk Gretzke

Dirk Gretzke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diarylcycloalkyl derivatives, process for their preparation and their use as pharmaceuticals
    Patent number: 7160911
    Abstract: Diarylcycloalkyl derivatives, process for their preparation and their use as pharmaceuticals The invention relates to diarylcycloalkyl derivatives and to their physiologically acceptable salts, racemates and physiologically functional derivatives. What is described are compounds of the formula I, in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparation. The compounds are suitable for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders as well as of disorders in which insulin resistence is involved.
    Type: Grant
    Filed: February 27, 2004
    Date of Patent: January 9, 2007
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Jochen Goerlitzer, Heiner Glombik, Eugen Falk, Dirk Gretzke, Stefanie Keil, Hans-Ludwig Schaefer, Christian Stapper, Wolfgang Wendler
  • Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals
    Patent number: 7148246
    Abstract: Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals The invention relates to cycloalkyl derivatives having bioisosteric carboxylic acid groups and to their physiologically acceptable salts and physiologically functional derivatives. What is described are compounds of the formula I, in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparations. The compounds are suitable for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders as well as of disorders in which insulin resistence is involved.
    Type: Grant
    Filed: February 27, 2004
    Date of Patent: December 12, 2006
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Dirk Gretzke, Heiner Glombik, Eugen Falk, Jochen Goerlitzer, Stefanie Keil, Hans-Ludwig Schaefer, Christian Stapper, Wolfgang Wendler
  • Cycloalkyl-substituted amino acid derivatives, processes for their preparation and their use as pharmaceuticals
    Publication number: 20050215596
    Abstract: Provided herein are cycloalkyl-substituted amino acid derivatives, processes for their preparation and their use as pharmaceuticals
    Type: Application
    Filed: February 27, 2004
    Publication date: September 29, 2005
    Applicant: Aventis Pharma Deutschland GMBH
    Inventors: Christian Stapper, Stefanie Keil, Heiner Glombik, Eugen Falk, Jochen Goerlitzer, Dirk Gretzke, Hans-Ludwig Schaefer, Wolfgang Wendler
  • Cycloalkylmethoxy-substituted acetic acid derivatives, processes for their preparation and their use as pharmaceuticals
    Publication number: 20050101637
    Abstract: Provided herein are novel compounds of formula I below: in which the radicals are as defined, their physiologically acceptable salts, processes for their preparation, as well as methods of treating and/or preventing disorders of disorders of fatty acid metabolism and glucose utilization disorders, and also of disorders in which insulin resistance is involved, in a patient.
    Type: Application
    Filed: February 27, 2004
    Publication date: May 12, 2005
    Applicant: Aventis Pharma Deutschland GMBH
    Inventors: Christian Stapper, Stefanie Keil, Heiner Glombik, Eugen Falk, Jochen Goerlitzer, Dirk Gretzke, Hans-Ludwig Schaefer, Wolfgang Wendler
  • Substituted N-aryl heterocycles, process for their preparation and their use as medicaments
    Publication number: 20040220191
    Abstract: The invention relates to substituted N-aryl heterocycles and to the physiologically tolerated salts and physiologically functional derivatives thereof.
    Type: Application
    Filed: February 17, 2004
    Publication date: November 4, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Lothar Schwink, Siegfried Stengelin, Matthias Gossel, Thomas Boehme, Gerhard Hessler, Petra Stahl, Dirk Gretzke
  • Cycloalkyl-substituted alkanoic acid derivatives, processes for their preparation and their use as pharmaceuticals
    Publication number: 20040220261
    Abstract: The invention relates to arylcycloalkyl-substituted derivatives and to their physiologically acceptable salts and physiologically functional derivatives.
    Type: Application
    Filed: February 27, 2004
    Publication date: November 4, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Christian Stapper, Heiner Glombik, Eugen Falk, Dirk Gretzke, Jochen Goerlitzer, Stefanie Keil, Hans-Ludwig Schaefer, Wolfgang Wendler
  • Arylcycloalkyl derivatives having branched side chains, processes for their preparation and their use as pharmaceuticals
    Publication number: 20040209873
    Abstract: Arylcycloalkyl derivatives having branched side chains, processes for their preparation and their use as pharmaceuticals
    Type: Application
    Filed: February 27, 2004
    Publication date: October 21, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Christian Stapper, Heiner Glombik, Eugen Falk, Jochen Goerlitzer, Dirk Gretzke, Stefanie Keil, Hans-Ludwig Schaefer, Wolfgang Wendler
  • 1,3-substitued cycloalkyl derivatives having acidic, mostly heterocyclic groups; processes for their preparation and their use as pharmaceuticals
    Publication number: 20040209932
    Abstract: The invention relates to 1,3-substituted cycloalkyl derivatives having acidic, mostly heterocyclic groups and to their physiologically acceptable salts and physiologically functional derivatives.
    Type: Application
    Filed: February 27, 2004
    Publication date: October 21, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Jochen Goerlitzer, Heiner Glombik, Eugen Falk, Dirk Gretzke, Stefanie Keil, Hans-Ludwig Schaefer, Christian Stapper, Wolfgang Wendler
  • Arylcycloalkyl-substituted alkanoic acid derivatives, processes for their preparation and their use as pharmaceuticals
    Publication number: 20040209920
    Abstract: Arylcycloalkyl-substituted alkanoic acid derivatives, processes for their preparation and their use as pharmaceuticals
    Type: Application
    Filed: February 27, 2004
    Publication date: October 21, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Christian Stapper, Stefanie Keil, Heiner Glombik, Eugen Falk, Jochen Goerlitzer, Dirk Gretzke, Hans-Ludwig Schaefer, Wolfgang Wendler
  • Diarylcycloalkyl derivatives, process for their preparation and their use as pharmaceuticals
    Publication number: 20040204462
    Abstract: Diarylcycloalkyl derivatives, process for their preparation and their use as pharmaceuticals
    Type: Application
    Filed: February 27, 2004
    Publication date: October 14, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Jochen Goerlitzer, Heiner Glombik, Eugen Falk, Dirk Gretzke, Stefanie Keil, Hans-Ludwig Schaefer, Christian Stapper, Wolfgang Wendler
  • Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals
    Publication number: 20040198786
    Abstract: Cycloalkyl derivatives having bioisosteric carboxylic acid groups, processes for their preparation and their use as pharmaceuticals
    Type: Application
    Filed: February 27, 2004
    Publication date: October 7, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Dirk Gretzke, Heiner Glombik, Eugen Falk, Jochen Goerlitzer, Stefanie Keil, Hans-Ludwig Schaefer, Christian Stapper, Wolfgang Wendler