Patents by Inventor Dirk Heerding

Dirk Heerding has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of Akt Activity
    Publication number: 20080255143
    Abstract: Invented are novel 1H-imidazo[4,5-c]pyridin-2-yl compounds, the use of such compounds as inhibitors of protein kinase B activity and in the treatment of cancer and arthritis.
    Type: Application
    Filed: July 28, 2004
    Publication date: October 16, 2008
    Applicant: SMITHKLINE BEECHAM CORPORATION
    Inventors: Dirk A. Heerding, Tammy J. Clark, David Harold Drewry, Jack Dale Leber, Igor Safonov, Dennis S. Yamashita
  • Thrombopoietin mimetics
    Patent number: 7414040
    Abstract: Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
    Type: Grant
    Filed: June 6, 2003
    Date of Patent: August 19, 2008
    Assignee: SmithKline Beecham Corporation
    Inventor: Dirk A. Heerding
  • Inhibitors of Akt activity
    Publication number: 20080076763
    Abstract: Invented are novel 1H-imidazo[4,5-c]pyridin-2-yl compounds, the use of such compounds as inhibitors of protein kinase B activity and in the treatment of cancer and arthritis.
    Type: Application
    Filed: June 27, 2007
    Publication date: March 27, 2008
    Inventors: Dirk Heerding, Tammy Clark, Jack Leber, Igor Safonov
  • Thrombopoietin mimetics
    Publication number: 20060084682
    Abstract: Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected benzimidazole derivative.
    Type: Application
    Filed: December 12, 2003
    Publication date: April 20, 2006
    Inventors: Dirk Heerding, Alan Price, Igor Safonov
  • Thrombopoietin mimetics
    Publication number: 20050234020
    Abstract: Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
    Type: Application
    Filed: June 6, 2003
    Publication date: October 20, 2005
    Inventor: Dirk Heerding
  • Disubstituted imidazoles useful in the treatment of bacterial infections
    Patent number: 6673941
    Abstract: Compounds of formula (I) and formula (II) are disclosed which are useful in the treatment bacterial infections: wherein: R1 is C1-4alkyl, Ar or 2-thienyl or 3-thienyl; R2 is C1-4alkyl or Ar; and n is 0-3; or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: January 9, 2003
    Date of Patent: January 6, 2004
    Assignee: Affinium Pharmaceuticals, Inc.
    Inventors: Dirk Heerding, Kenneth A. Newlander
  • Vitronectin receptor antagonist
    Publication number: 20030216377
    Abstract: A compound of the formula (I) is disclosed which is a vitronectin receptor antagonist and is useful in the treatment of osteoporosis: 1
    Type: Application
    Filed: May 5, 2003
    Publication date: November 20, 2003
    Applicant: SmithKline Beecham Corporation
    Inventor: Dirk Heerding
  • Fibrinogen receptor antagonists
    Publication number: 20030212076
    Abstract: This invention relates to a compound of the formula (I): 1
    Type: Application
    Filed: April 10, 2003
    Publication date: November 13, 2003
    Applicant: SmithKline Beecham Corporation
    Inventors: Dirk A. Heerding, James Martin Samanen
  • Antibacterial compounds
    Publication number: 20030149089
    Abstract: Compounds of formula (I) and formula (II) are disclosed which are useful in the treatment bacterial infections: 1
    Type: Application
    Filed: January 9, 2003
    Publication date: August 7, 2003
    Applicant: SmithKline Beecham Corporation
    Inventors: Dirk Heerding, Kenneth A. Newlander
  • Vitronectin receptor antagonists
    Patent number: 6576643
    Abstract: Compounds of the formula (I) are disclosed which are vitronectin receptor antagonists and are useful in the treatment of osteoporosis: or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: December 17, 2001
    Date of Patent: June 10, 2003
    Assignee: SmithKline Beecham Corporation
    Inventors: William E. Bondinell, William H. Miller, Dirk Heerding, James M. Samanen
  • Vitronectin receptor antagonist
    Publication number: 20030087894
    Abstract: A compound of the formula (I) is disclosed which is a vitronectin receptor antagonist and is useful in the treatment of osteoporosis: 1
    Type: Application
    Filed: October 22, 2002
    Publication date: May 8, 2003
    Applicant: SmithKline Beecham Corporation
    Inventor: Dirk Heerding
  • Disubstituted imidazoles useful in the treatment of bacterial infections
    Patent number: 6559172
    Abstract: Novel disubstituted imidazoles are disclosed which are useful in the treatment of bacterial infections, particularly through the inhibition of FAB I.
    Type: Grant
    Filed: November 14, 2001
    Date of Patent: May 6, 2003
    Assignee: SmithKline Beecham Corporation
    Inventors: Dirk Heerding, Kenneth A. Newlander
  • Vitronectin Receptor Antagonists
    Publication number: 20020147334
    Abstract: Compounds of the formula (1) are disclosed which are vitronectin receptor antagonists and are useful in the treatment of osteoporosis: 1
    Type: Application
    Filed: February 26, 2002
    Publication date: October 10, 2002
    Applicant: SmithKline Beecham Corporation
    Inventors: William H. Miller, John G. Gleason, Dirk Heerding, James M. Samanen, Irene N. Uzinskas, Peter J. Manley
  • Vitronectin receptor antagonist
    Publication number: 20020128257
    Abstract: A compound of the formula (I) is disclosed which is a vitronectin receptor antagonist and is useful in the treatment of osteoporosis: 1
    Type: Application
    Filed: May 8, 2002
    Publication date: September 12, 2002
    Applicant: SmithKline Beecham Corporation
    Inventor: Dirk Heerding
  • Vitronectin receptor antagonists
    Publication number: 20020091264
    Abstract: Compounds of the formula (I) are disclosed which are vitronectin receptor antagonists and are useful in the treatment of osteoporosis: 1
    Type: Application
    Filed: December 17, 2001
    Publication date: July 11, 2002
    Applicant: SmithKline Beecham Corporation
    Inventors: William E. Bondinell, William H. Miller, Dirk Heerding, James M. Samanen
  • Fibrinogen receptor antagonists
    Publication number: 20020065288
    Abstract: This invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof, which is effective for inhibiting platelet aggregation, pharmaceutical compositions for effecting such activity, and a method for inhibiting platelet aggregation.
    Type: Application
    Filed: November 28, 2001
    Publication date: May 30, 2002
    Applicant: SmithKline Beecham Corporation
    Inventors: Dirk A. Heerding, James Martin Samanen
  • Integrin receptor antagonists
    Publication number: 20020055499
    Abstract: Compounds of the formula (I) are disclosed which are dual fibrinogen receptor and vitronectin receptor antagonists and are useful in the treatment of atherosclerosis, in the prevention of restenosis and in the prevention of tumor metastasis and tumor growth: 1
    Type: Application
    Filed: December 12, 2001
    Publication date: May 9, 2002
    Inventors: Dirk Heerding, James Martin Samanen
  • Vitronectin receptor antagonist
    Publication number: 20020040136
    Abstract: A compound of the formula (I) is disclosed which is a vitronectin receptor antagonist and is useful in the treatment of osteoporosis: 1
    Type: Application
    Filed: November 28, 2001
    Publication date: April 4, 2002
    Applicant: SmithKline Beecham Corporation
    Inventor: Dirk Heerding
  • Vitronectin receptor antagonist
    Publication number: 20010014737
    Abstract: A compound of the formula (I) is disclosed which is a vitronectin receptor antagonist and is useful in the treatment of osteoporosis: 1
    Type: Application
    Filed: March 5, 2001
    Publication date: August 16, 2001
    Inventor: Dirk Heerding
  • Fibrinogen receptor antagonists
    Publication number: 20010014682
    Abstract: This invention relates to a compound of the formula (I): 1
    Type: Application
    Filed: April 23, 2001
    Publication date: August 16, 2001
    Applicant: SmithKline Beecham Corporation
    Inventors: Dirk A. Heerding, James Martin Samanen