Abstract: Provided herein are Receptor Elimination by E3 Ubiquitin Ligase Recruitment (REULR) constructs and related compositions, kits, methods of use and methods of production. REULR constructs comprise a variable domain heavy chain antibody (VHH) specific for a E3 Ubiquitin Ligase, and a VHH specific for a target protein, where in the E3 Ubiquitin Ligase and the target protein are different. REULR constructs described here target proteins associated with many maladies, but especially cancer.

Abstract: The invention describes an illuminated serving tray that comprises a platter (1) through which light can pass, at least one sheet-like light source (7, 7?) disposed beneath the platter (1) for illuminating the illuminated serving tray and/or food (4), drinks (5) or other articles placed on the illuminated serving tray. The sheet-like light source (7, 7?) radiates light uniformly and thus producing uniform illumination of the objects placed on the illuminated serving tray. The illuminated serving tray may also comprise a cover (3) which may also be illuminated by the sheet-like light source (7, 7?). A system for charging the rechargeable energy storage devices (8) is also described. A method of changing the appearance of the illuminated serving tray, using at least partly reflective matter (11) is also disclosed.

Abstract: The invention relates to an airbag system for motor vehicles, integrated in an inner trim piece, in particular, in a dashboard (16), comprising an airbag (5, 5′, 5″), which is inflatable by means of a gas generator (8, 8′, 8″). The inner trim piece comprises at least one dimensionally stable support (1, 1′,k 1″) and an airbag cover (2, 2′, 2″), which opens outwards under the pressure of the airbag (5, 5′, 5″) filling with gas. The airbag cover (2, 2′, 2″) is flexible and designed to yield to the pressure of the filling airbag (5, 5′, 5″). The airbag (5, 5′, 5″) is arranged under the cover (2, 2′, 2″) in a housing (4, 4′, 4″), connected to the support (1, 1′, 1″).