Patents by Inventor Dirk Inzé

Dirk Inzé has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080307546
    Abstract: Provided are DNA sequences encoding cyclin-dependent kinase inhibitor(s) as well as to methods for obtaining the same. Furthermore, vectors comprising said DNA sequences are described, wherein the DNA sequences are operatively linked to regulatory elements allowing expression in prokaryotic and/or eukaryotic host cells. In addition, proteins encoded by said DNA sequences, antibodies to said proteins and methods for their production are provided. Furthermore, regulatory sequences which naturally regulate the expression of the above described DNA sequences are described. Also described is a method for controlling or altering growth characteristics of a plant and/or a plant cell comprising introduction and/or expression of one or more cyclin-dependent kinase inhibitor(s) functional in a plant or parts thereof and/or one or more DNA sequences encoding such proteins.
    Type: Application
    Filed: March 26, 2007
    Publication date: December 11, 2008
    Inventors: Lieven De Veylder, Tom Beeckman, Dirk Inze, Wim Van Camp, Luc Krols
  • Publication number: 20080301833
    Abstract: The present invention relates to the field of plant molecular biology. In particular, it describes the use of a regulatory nucleic acid sequence of the rice gene GOS2 for the regulation of gene expression in plant cells derived from plants other than monocotyledonous plants. The use of the regulatory sequence of the present invention results in constitutive expression with expression levels similar to that of CaMV 35S. The present invention also relates to vectors and host cells comprising these nucleic acid sequences. The invention further relates to transgenic cells and plants comprising these sequences and to methods for obtaining such cells and plants.
    Type: Application
    Filed: May 14, 2007
    Publication date: December 4, 2008
    Applicant: CropDesign N.V.
    Inventors: Yves Hatzfeld, Dirk Inze
  • Publication number: 20080207449
    Abstract: The invention provides isolated nucleic acids molecules, designated CCP nucleic acid molecules, which encode novel cell cycle associated polypeptides. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing CCP, nucleic acid molecules, host cells into which the expression vectors have been introduced, and transgenic plants in which a CCP gene has been introduced or disrupted. The invention still further provides isolated CCP proteins, fusion proteins, antigenic peptides and anti-CCP antibodies. Agricultural, diagnostic, screening, and therapeutic methods utilizing compositions or the invention are also provided.
    Type: Application
    Filed: May 14, 2001
    Publication date: August 28, 2008
    Applicant: CROPDESIGN N.V.
    Inventors: Dirk Inze, Veronique Boudolf, Lieven De Veylder, Juan Antonio Torres Acosta, Zoltan Magyar
  • Publication number: 20080127365
    Abstract: The present invention relates generally to the field of molecular biology and concerns a method for improving plant growth characteristics relative to corresponding wild type plants. More specifically, the present invention concerns a method for improving plant growth characteristics comprising modulating expression in a plant of a nucleic acid encoding a class I homeodomain leucine zipper (HDZip) hox5 polypeptide or a homologue thereof; or comprising modulating expression in a plant of a nucleic acid encoding a nitrate transporter protein (NRT) or a homologue thereof; or comprising modulating expression in a plant of a nucleic acid encoding a polypeptide denoted Yield Enhancing Protein 16 (YEP16); or comprising modulating expression in a plant of a Group I glycogen synthase kinase (Group I shaggy-like kinase) or a homologue thereof.
    Type: Application
    Filed: April 30, 2007
    Publication date: May 29, 2008
    Applicant: CropDesign N.V.
    Inventors: Ana Isabel Sanz Molinero, Christophe Reuzeau, Yves Hatzfeld, Veronique Boudolf, Lieven de Veylder, Dirk Inze, Vladimir Mironov
  • Patent number: 7265267
    Abstract: Provided are DNA sequences encoding cyclin-dependent kinase inhibitor(s) as well as to methods for obtaining the same. Furthermore, vectors comprising said DNA sequences are described, wherein the DNA sequences are operatively linked to regulatory elements allowing expression in prokaryotic and/or eukaryotic host cells. In addition, proteins encoded by said DNA sequences, antibodies to said proteins and methods for their production are provided. Furthermore, regulatory sequences which naturally regulate the expression of the above described DNA sequences are described. Also described is a method for controlling or altering growth characteristics of a plant and/or a plant cell comprising introduction and/or expression of one or more cyclin-dependent kinase inhibitor(s) functional in a plant or parts thereof and/or one or more DNA sequences encoding such proteins.
    Type: Grant
    Filed: May 18, 2000
    Date of Patent: September 4, 2007
    Assignee: CropDesign N.V.
    Inventors: Lieven De Veylder, Tom Beeckman, Dirk Inze, Wim Van Camp, Luc Krols
  • Patent number: 7235710
    Abstract: The present invention relates to the field of plant molecular biology. In particular, it describes the use of a regulatory nucleic acid sequence of the rice gene GOS2 for the regulation of gene expression in plant cells derived from plants other than monocotyledonous plants. The use of the regulatory sequence of the present invention results in constitutive expression with expression levels similar to that of CaMV 35S. The present invention also relates to vectors and host cells comprising these nucleic acid sequences. The invention further relates to transgenic cells and plants comprising these sequences and to methods for obtaining such cells and plants.
    Type: Grant
    Filed: January 21, 2004
    Date of Patent: June 26, 2007
    Assignee: Cropdesign N.V.
    Inventors: Yves Hatzfeld, Dirk Inze
  • Publication number: 20070136889
    Abstract: The present invention provides a new Arabidopsis thaliana nucleotide sequence and polypeptide sequence having a molecular weight of about 10.5 kDa. Modulation of the expression of the polypeptides encoded by the nucleotide sequences according to the invention has an advantageous influence on plant cell division characteristics especially on the endoreduplication whereby plant cell size and storage capacity of plant cells is influenced.
    Type: Application
    Filed: January 26, 2007
    Publication date: June 14, 2007
    Inventors: Dirk Inze, Gerda Segers, Lieven Veylder, Vladimir Mironov
  • Publication number: 20060053507
    Abstract: The present invention relates to the field of plant molecular biology. In particular, it describes the use of a regulatory nucleic acid sequence of the rice gene GOS2 for the regulation of gene expression in plant cells derived from plants other than monocotyledonous plants. The use of the regulatory sequence of the present invention results in constitutive expression with expression levels similar to that of CaMV 35S. The present invention also relates to vectors and host cells comprising these nucleic acid sequences. The invention further relates to transgenic cells and plants comprising these sequences and to methods for obtaining such cells and plants.
    Type: Application
    Filed: January 21, 2004
    Publication date: March 9, 2006
    Inventors: Yves Hatzfeld, Dirk Inze
  • Publication number: 20060041962
    Abstract: The present invention relates to the use of a genome wide expression profiling technology in combination with the detection of the presence of secondary metabolites of interest to isolate genes that can be used to modulate the production of secondary metabolites in organisms and cell lines derived therefrom.
    Type: Application
    Filed: November 16, 2004
    Publication date: February 23, 2006
    Inventors: Dirk Inze, Alain Goossens, Kirsi-Marja Oksman-Caldentey, Suvi Hakkinen, Into Laakso
  • Publication number: 20060029995
    Abstract: The invention relates to a novel class of metacaspases. More particularly, the present invention relates to the use of metacaspases, preferably plant metacaspases to process a protein at a cleavage site comprising an arginine or a lysine at the P1 position, and to the use of such metacaspases to modulate cell death.
    Type: Application
    Filed: September 12, 2005
    Publication date: February 9, 2006
    Applicants: Vlaams Interuniversitair Instituut Voor Biotechnologie VZW, Universiteit Gent
    Inventors: Dirk Inze, Frank Van Breusegem, Dominique Vercammen, Brigitte Van De Cotte
  • Publication number: 20060021088
    Abstract: The present invention concerns a method for altering characteristics of a plant. The invention describes the identification of genes that are upregulated or downregulated in transgenic plants overexpressing E2Fa/DPa and the use of such sequences to alter plant characteristics. A preferred way for altering characteristics of a plant comprises modifying expression of one or more nucleic acid sequences and or modifying level and/or activity of one or more proteins, which nucleic acids and/or proteins are essentially similar to any one or more of SEQ ID NO 1 to 2755. Some of the genes identified in the present invention have an E2Fa target consensus sequence in their 5? upstream region. The identified genes play a role in a variety of biological processes, such as DNA replication, cell wall biosynthesis, nitrogen and/or carbon metabolism, transcription factors etc.
    Type: Application
    Filed: October 20, 2003
    Publication date: January 26, 2006
    Inventors: Dirk Inze, Lieven Veylder, Kobe Vlieghe
  • Publication number: 20050221290
    Abstract: The invention relates to a method for identifying and validating plant targets for agrochemicals, comprising the steps of determining gene or protein expression profiles in function of the progression of an essential biological process in a plant, and the subsequent downregulation of expression of said gene or protein in a plant cell. More particularly, the effects of downregulation of the candidate target gene were directly monitored on plants locally infected with a vector mediating viral induced gene suppression in that infected plant area. The invention also relates to isolated plant genes encoding proteins involved in plant growth and development. The invention also relates to plants tolerant to agrochemicals such as herbicides or pesticides.
    Type: Application
    Filed: April 8, 2003
    Publication date: October 6, 2005
    Inventors: Dirk Inze, Willem Broekaert
  • Publication number: 20050059154
    Abstract: The present invention relates to a method for modifying plant growth and development processes by affecting cell cycle regulation comprising modulating expression of members of the plant E2F transcription factor family. More specific the invention relates to methods for stimulating cell division in a plant. The invention further relates to transgenic plants produced by the methods of the invention having altered plant growth and development characteristics compared to their isogenic counterparts. Preferably, the plant characteristics modified by the present invention include enlarged cotyledons, enhanced growth rate, stress resistance and seedling survival, more cells, more tillers, more panicles.
    Type: Application
    Filed: September 12, 2002
    Publication date: March 17, 2005
    Inventors: Tom Beeckman, Lieven De Veylder, Dirk Inze, Vladimir Mironov, Willem Broekaert, Willy Dillen, Valerie Frankard
  • Publication number: 20050044592
    Abstract: The present invention relates to the use of one or more genes, encoding a protein of the elongator complex to modulate plant growth. More specifically, the invention relates to the overexpression of the DRL1 gene, to simulate growth of leaves and roots.
    Type: Application
    Filed: August 9, 2004
    Publication date: February 24, 2005
    Inventors: Hilde Nelissen, Lieven Deveylder, Jonathan Clarke, Dirk Inze, Maria Lijsebettens
  • Publication number: 20040209273
    Abstract: The present invention relates to a method to isolate plant genes or gene fragments that are regulated by stress, preferably oxidative stress. The method includes isolation of plant material, adaptation of the plant material to stress, differential expression of genes or gene fragments in adapted and nonadapted plant material, and isolation of the differentially expressed genes or gene fragments. The invention further relates to the genes or gene fragments that can be obtained by this method and to the use of these genes or gene fragments to modulate plant stress tolerance.
    Type: Application
    Filed: August 25, 2003
    Publication date: October 21, 2004
    Inventors: Eva Vranova, Dirk Inze, Frank Van Breusegem, Wim Van Camp
  • Publication number: 20040073969
    Abstract: Provided are DNA sequences encoding cyclin-dependent kinase inhibitor(s) as well as to methods for obtaining the same. Furthermore, vectors comprising said DNA sequences are described, wherein the DNA sequences are operatively linked to regulatory elements allowing expression in prokaryotic and/or eukaryotic host cells. In addition, proteins encoded by said DNA sequences, antibodies to said proteins and methods for their production are provided. Furthermore, regulatory sequences which naturally regulate the expression of the above described DNA sequences are described. Also described is a method for controlling or altering growth characteristics of a plant and/or a plant cell comprising introduction and/or expression of one or more cyclin-dependent kinase inhibitor(s) functional in a plant or parts thereof and/or one or more DNA sequences encoding such proteins.
    Type: Application
    Filed: October 17, 2003
    Publication date: April 15, 2004
    Inventors: Dirk Inze, Lieven De Veylder, Janice De Almeida, Isabelle Landrieu
  • Patent number: 6710227
    Abstract: Provided are DNA sequences encoding cyclin-dependent kinase inhibitor(s) as well as to methods for obtaining the same. Furthermore, vectors comprising said DNA sequences are described, wherein the DNA sequences are operatively linked to regulatory elements allowing expression in prokaryotic and/or eukaryotic host cells. In addition, proteins encoded by said DNA sequences, antibodies to said proteins and methods for their production are provided. Furthermore, regulatory sequences which naturally regulate the expression of the above described DNA sequences are described. Also described is a method for controlling or altering growth characteristics of a plant and/or a plant cell comprising introduction and/or expression of one or more cyclin-dependent kinase inhibitor(s) functional in a plant or parts thereof and/or one or more DNA sequences encoding such proteins.
    Type: Grant
    Filed: March 16, 2000
    Date of Patent: March 23, 2004
    Assignee: CropDesign N.V.
    Inventors: Dirk Inze, Lieven De Veylder, Janice De Almeida, Isabelle Landrieu
  • Publication number: 20040019926
    Abstract: The invention provides isolated nucleic acids molecules, designated ICK nucleic acid molecules, which encode novel plant cyclin-dependent kinase inhibitors. The invention also provides antisense nucleic acid molecules, gene silencing and recombinant expression vectors containing ICK nucleic acid molecules, host cells into which the expression vectors have been introduced, and transgenic plants in which an ICK gene has been introduced or disrupted. The invention still further provides isolated ICK proteins, fusion proteins, antigenic peptides and anti-ICK antibodies. Agricultural, diagnostic, and screening methods utilizing compositions of the invention are also provided.
    Type: Application
    Filed: January 14, 2003
    Publication date: January 29, 2004
    Inventors: Valerie Marie-Noelle S. Frankard, Adrian Marius Peres Bota, Anne-Marie Droual, Vladimir Mironov, Dirk Inze, Yves Hatzfeld
  • Patent number: 6677506
    Abstract: An isolated DNA molecule is provided coding for a polypeptide of the 11-12 transmembrane domain transporter family having a Mg2+/H+ or Zn2+/H+ exchange activity, herein designated MHX. The genomic MHX DNA was isolated from Arabidopsis thaliana cv. C-24. Transgenic plants transformed with said DNA and expressing MHX are shown to have a lower content of sodium as compared with corresponding wild-type plants or a higher dry matter weight upon growth in calcium-rich media as compared with corresponding wild-type plants. These transgenic plants are tolerant to stress conditions, particularly high salinity and calcium-rich media, e.g. saline and calcareous soils.
    Type: Grant
    Filed: November 24, 2000
    Date of Patent: January 13, 2004
    Assignees: Yeda Research and Development Co. Ltd., The University of Texas System
    Inventors: Gad Galili, Orit Shaul, Dirk Inze, Marc Van Montagu, Donald W. Hilgemann
  • Publication number: 20030014777
    Abstract: The present invention provides a new Arabidopsis thaliana nucleotide sequence and polypeptide sequence having a molecular weight of about 10.5 kDa.
    Type: Application
    Filed: August 22, 2002
    Publication date: January 16, 2003
    Inventors: Dirk Inze, Gerda Segers, Lieven De Veylder, Vladimir Mironov