Patents by Inventor Dirk Jager

Dirk Jager has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cancer therapy with an oncolytic virus combined with a checkpoint inhibitor
    Patent number: 11964015
    Abstract: The present invention concerns a pharmaceutical composition where a checkpoint inhibitor is combined with an oncolytic virus and the use of said combination for the treatment of cancer.
    Type: Grant
    Filed: April 9, 2021
    Date of Patent: April 23, 2024
    Assignees: DEUTSCHES KREBSFORSCHUNGSZENTRUM, RUPRECHT-KARLS-UNIVERSITAT HEIDELBERG
    Inventors: Barbara Leuchs, Antonio Marchini, Jean Rommelaere, Assia Angelova, Dirk Jager, Wolfgang Wick, Michael Dahm
  • CANCER THERAPY WITH AN ONCOLYTIC VIRUS COMBINED WITH A CHECKPOINT INHIBITOR
    Publication number: 20210228714
    Abstract: The present invention concerns a pharmaceutical composition where a checkpoint inhibitor is combined with an oncolytic virus and the use of said combination for the treatment of cancer.
    Type: Application
    Filed: April 9, 2021
    Publication date: July 29, 2021
    Inventors: Barbara Leuchs, Antonio Marchini, Jean Rommelaere, Assia Angelova, Dirk Jager, Wolfgang Wick, Michael Dahm
  • Cancer therapy with an oncolytic virus combined with a checkpoint inhibitor
    Patent number: 11027013
    Abstract: The present invention concerns a pharmaceutical composition where a checkpoint inhibitor is combined with an oncolytic virus and the use of said combination for the treatment of cancer.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: June 8, 2021
    Assignees: DEUTSCHES KREBSFORSCHUNGSZENTRUM, RUPRECHT-KARLS-UNIVERSITAT HEIDELBERG
    Inventors: Barbara Leuchs, Antonio Marchini, Jean Rommelaere, Assia Angelova, Dirk Jager, Wolfgang Wick, Michael Dahm
  • USE OF CCR5 ANTAGONISTS ALONE OR IN COMBINATION THERAPY FOR THE TREATMENT OF CANCER
    Publication number: 20210000816
    Abstract: The present invention relates to CCRS antagonists for use in the treatment of cancer, either in monotherapy or in combination therapy. The invention also relates to methods for determining whether a subject suffering from cancer benefits from an ongoing therapeutic treatment with a CCRS antagonist or whether a subject suffering from cancer will benefit from a planned therapeutic treatment with a CCRS antagonist.
    Type: Application
    Filed: July 20, 2020
    Publication date: January 7, 2021
    Inventors: Niels HALAMA, Dirk JAGER, Inka ZOERNIG, Niels GRABE
  • CANCER THERAPY WITH AN ONCOLYTIC VIRUS COMBINED WITH A CHECKPOINT INHIBITOR
    Publication number: 20190117768
    Abstract: The present invention concerns a pharmaceutical composition where a checkpoint inhibitor is combined with an oncolytic virus and the use of said combination for the treatment of cancer.
    Type: Application
    Filed: October 1, 2018
    Publication date: April 25, 2019
    Inventors: Barbara Leuchs, Antonio Marchini, Jean Rommelaere, Assia Angelova, Dirk Jager, Wolfgang Wick, Michael Dahm
  • SEROMIC ANALYSIS OF OVARIAN CANCER
    Publication number: 20120283115
    Abstract: The invention relates to the discovery of cancer antigens associated with ovarian cancer. In further aspects, the invention relates to methods, compositions and kits for the diagnosis and treatment of cancer, particularly ovarian and pancreatic cancers.
    Type: Application
    Filed: August 30, 2010
    Publication date: November 8, 2012
    Applicant: Ludwig Institute for Cancer Research Ltd.
    Inventors: Gerd Ritter, Lloyd J. Old, Constance Old, Sacha Gnjatic, Kunle Odunsi, Dirk Jager
  • Isolated nucleic acid molecules encoding cancer associated antigens, the antigens per se, and uses thereof
    Patent number: 8071717
    Abstract: The invention relates to newly identified cancer associated antigens. It has been discovered that each of these molecules provokes antibodies when expressed by a subject. The ramifications of this observation are also a part of this invention.
    Type: Grant
    Filed: October 27, 2009
    Date of Patent: December 6, 2011
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Dirk Jager, Elisabeth Stockert, Matthew Scanlan, Alexander Knuth, Lloyd Old, Ali Gure, Yao-Tseng Chen, Elke Jager
  • Isolated nucleic acid molecules encoding cancer associated antigens, the antigens per se, and uses thereof
    Publication number: 20100278850
    Abstract: The invention relates to newly identified cancer associated antigens. It has been discovered that each of these molecules provokes antibodies when expressed by a subject. The ramifications of this observation are also a part of this invention.
    Type: Application
    Filed: October 27, 2009
    Publication date: November 4, 2010
    Inventors: Dirk Jager, Elisabeth Stockert, Matthew Scanlan, Alexander Knuth, Lloyd Old, Ali Gure, Yao-Tseng Chen, Elke Jager
  • Isolated nucleic acid molecules encoding cancer associated antigens, the antigens per se, and uses thereof
    Patent number: 7795379
    Abstract: The invention relates to newly identified cancer associated antigens. It has been discovered that each of these molecules provokes antibodies when expressed by a subject. The ramifications of this observation are also a part of this invention.
    Type: Grant
    Filed: September 6, 2005
    Date of Patent: September 14, 2010
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Elke Jager, Dirk Jager, Alexander Knuth
  • Isolated nucleic acid molecules encoding cancer associated antigens, the antigens per SE, and uses thereof
    Patent number: 7795409
    Abstract: The invention relates to newly identified cancer associated antigens. It has been discovered that each of these molecules provokes antibodies when expressed by a subject. The ramifications of this observation are also a part of this invention.
    Type: Grant
    Filed: January 30, 2008
    Date of Patent: September 14, 2010
    Assignees: Ludwig Institute for Cancer Research, Cornell Research Foundation, Inc.
    Inventors: Dirk Jager, Elisabeth Stockert, Barry C. Picker, legal representative, Matthew Scanlan, Cynthia H. Scanlan, legal representative, Ali Gure, Elke Jager, Alexander Knuth, Lloyd Old, Yao-Tseng Chen
  • Isolated nucleic acid molecules encoding cancer associated antigens, the antigens per se, and uses thereof
    Patent number: 7622568
    Abstract: The invention relates to newly identified cancer associated antigens. It has been discovered that each of these molecules provokes antibodies when expressed by a subject. The ramifications of this observation are also a part of this invention.
    Type: Grant
    Filed: November 12, 2007
    Date of Patent: November 24, 2009
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Dirk Jager, Elisabeth Stockert, Matthew Scanlan, Alexander Knuth, Lloyd Old, Ali Gure, Yao-Tseng Chen, Elke Jager
  • Isolated nucleic acid molecules encoding cancer associated antigens, the antigens per SE, and uses thereof
    Publication number: 20090203123
    Abstract: The invention relates to newly identified cancer associated antigens. It has been discovered that each of these molecules provokes antibodies when expressed by a subject. The ramifications of this observation are also a part of this invention.
    Type: Application
    Filed: January 30, 2008
    Publication date: August 13, 2009
    Inventors: Dirk Jager, Elisabeth Stockert, Matthew Scanlan, Ali Gure, Elke Jager, Alexander Knuth, Lloyd Old, Yao-Tseng Chen, Barry C. Picker, Cynthia H. Scanlan
  • Isolated nucleic acid molecules encoding cancer associated antigens, the antigens per se, and uses thereof
    Publication number: 20080177031
    Abstract: The invention relates to newly identified cancer associated antigens. It has been discovered that each of these molecules provokes antibodies when expressed by a subject. The ramifications of this observation are also a part of this invention.
    Type: Application
    Filed: November 12, 2007
    Publication date: July 24, 2008
    Inventors: Dirk Jager, Elisabeth Stockert, Matthew Scanlan, Alexander Knuth, Lloyd Old, Ali Gure, Yao-Tseng Chen, Elke Jager
  • Isolated nucleic acid molecules encoding cancer associated antigens, the antigens per se, and uses thereof
    Patent number: 7354992
    Abstract: The invention relates to newly identified cancer associated antigens. It has been discovered that each of these molecules provokes antibodies when expressed by a subject. The ramifications of this observation are also a part of this invention.
    Type: Grant
    Filed: December 4, 2003
    Date of Patent: April 8, 2008
    Assignees: Ludwig Institute For Cancer Research, Cornell Research Foundation, Inc.
    Inventors: Dirk Jager, Barry C. Picker, legal representative, Cynthia H. Scanlan, legal representative, Ali Gure, Elke Jager, Alexander Knuth, Lloyd Old, Yao-Tseng Chen, Elisabeth Stockert, Matthew Scanlan
  • Small cell lung cancer associated antigens and uses therefor
    Patent number: 7314721
    Abstract: Cancer associated antigens have been identified by autologous antibody screening of libraries of nucleic acids expressed in small cell lung cancer cells using antisera from cancer patients. The invention relates to nucleic acids and encoded polypeptides which are cancer associated antigens expressed in patients afflicted with small cell lung cancer. The invention provides, among other things, isolated nucleic acid molecules, expression vectors containing those molecules and host cells transfected with those molecules. The invention also provides isolated proteins and peptides, antibodies to those proteins and peptides and cytotoxic T lymphocytes which recognize the proteins and peptides. Fragments of the foregoing including functional fragments and variants also are provided. Kits containing the foregoing molecules additionally are provided.
    Type: Grant
    Filed: January 20, 2004
    Date of Patent: January 1, 2008
    Assignees: Ludwig Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, New York Hospital-Cornell Medical Center
    Inventors: Ali O. Gure, Elisabeth Stockert, Matthew J. Scanlan, Dirk Jager, Lloyd J. Old, Yao-Tseng Chen
  • Isolated cancer associated antigens NY-MEL 1 and NY-MEL 3, peptides based thereon, and their uses
    Patent number: 7132507
    Abstract: The invention relates to isolated, cancer associated antigens, nucleic acid molecules, and various uses thereof.
    Type: Grant
    Filed: May 21, 2002
    Date of Patent: November 7, 2006
    Assignees: Ludwig Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, Cornell Research Foundation, Inc.
    Inventors: Dirk Jager, Elizabeth Stockert, Matthew Scanlan, Ali Gure, Elke Jager, Alexander Knuth, Lloyd Old, Yao-Tseng Chen
  • Isolated nucleic acid molecules encoding cancer associated antigens, the antigens per se, and uses thereof
    Publication number: 20060165651
    Abstract: The invention relates to newly identified cancer associated antigens. It has been discovered that each of these molecules provokes antibodies when expressed by a subject. The ramifications of this observation are also a part of this invention.
    Type: Application
    Filed: September 6, 2005
    Publication date: July 27, 2006
    Inventors: Elke Jager, Dirk Jager, Alexander Knuth
  • Isolated nucleic acid molecules encoding cancer associated antigens, the antigens per se, and uses thereof
    Patent number: 6911529
    Abstract: The invention relates to newly identified cancer associated antigens. It has been discovered that each of these molecules provokes antibodies when expressed by a subject. The ramifications of this observation are also part of this invention.
    Type: Grant
    Filed: June 22, 2000
    Date of Patent: June 28, 2005
    Assignees: Ludwig Institute for Cancer Research, Cornell Research Foundation, Memorial Sloan-Kettering Cancer Center
    Inventors: Dirk Jager, Elizabeth Stockert, Matthew Scanlan, Ali Gure, Elke Jager, Alexander Knuth, Lloyd Old, Yao-tseng Chen
  • Isolated nucleic acid molecules encoding cancer associated antigens, the antigens per se, and uses thereof
    Publication number: 20050063981
    Abstract: The invention relates to newly identified cancer associated antigens. It has been discovered that each of these molecules provokes antibodies when expressed by a subject. The ramifications of this observation are also a part of this invention.
    Type: Application
    Filed: December 4, 2003
    Publication date: March 24, 2005
    Inventors: Dirk Jager, Elisabeth Stockert, Barry Picker, Matthew Scanlan, Cynthia Scanlan, Ali Gure, Elke Jager, Alexander Knuth, Lloyd Old, Yao-Tseng Chen
  • Isolated nucleic acid molecules encoding cancer associated antigens, the antigens per se, and uses thereof
    Patent number: 6774226
    Abstract: The invention relates to newly identified cancer associated antigens. It has been discovered that each of these molecules provokes antibodies when expressed by a subject. The ramifications of this observation are also a part of this invention.
    Type: Grant
    Filed: November 30, 1999
    Date of Patent: August 10, 2004
    Assignees: Ludwig Institute for Cancer Research, Cornell Research Foundation, Inc.
    Inventors: Dirk Jager, Elizabeth Stockert, Matthew Scanlan, Ali Gure, Elke Jager, Alexander Knuth, Lloyd Old, Yao-tseng Chen