Patents by Inventor Dirk Johannes van den Boom

Dirk Johannes van den Boom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DETECTION AND QUANTIFICATION OF BIOMOLECULES USING MASS SPECTROMETRY
    Publication number: 20090111712
    Abstract: The present invention is directed in part to a method for detecting a target nucleic acid using detector oligonucleotides detectable by mass spectrometry. This method takes advantage of the 5? to 3? nuclease activity of a nucleic acid polymerase to cleave annealed oligonucleotide probes from hybridized duplexes and releases labels for detection by mass spectrometry. This process is easily incorporated into a polymerase chain reaction (PCR) amplification assay. The method also includes embodiments directed to quantitative analysis of target nucleic acids.
    Type: Application
    Filed: June 4, 2008
    Publication date: April 30, 2009
    Applicant: SEQUENOM, INC.
    Inventors: Dirk Johannes Van Den Boom, Paul Andrew Oeth, Payam Mahboubi
  • COMPARATIVE SEQUENCE ANALYSIS PROCESSES AND SYSTEMS
    Publication number: 20090006002
    Abstract: Provided herein are processes for rapidly identifying or determining sequence information in a sample nucleic acid by comparing sample nucleic acid sequence information to reference nucleic acid sequence information or information obtained from reference samples. Also provided are automated systems for conducting comparative sequence analyses.
    Type: Application
    Filed: April 11, 2008
    Publication date: January 1, 2009
    Applicant: SEQUENOM, INC.
    Inventors: Christiane Honisch, Yong Qing Chen, Dirk Johannes Van Den Boom
  • DETECTION AND QUANTIFICATION OF BIOMOLECULES USING MASS SPECTROMETRY
    Publication number: 20080305479
    Abstract: The present invention is directed in part to a method for detecting a target nucleic acid using detector oligonucleotides detectable by mass spectrometry. This method uses the 5? to 3? nuclease activity of a nucleic acid polymerase to cleave annealed oligonucleotide probes from hybridized duplexes and release labels for detection by mass spectrometry. This process is easily incorporated into a PCR amplification assay. The method also includes embodiments directed to quantitative analysis of target nucleic acids.
    Type: Application
    Filed: December 4, 2007
    Publication date: December 11, 2008
    Applicant: SEQUENOM, INC.
    Inventor: Dirk Johannes VAN DEN BOOM