Abstract: The present disclosure relates to the fields of packaging, transportation, and storage of temperature-sensitive materials, such as biological and/or pharmaceutical products. Various aspects of such packaging, transportation, and storage are provided herein for ultra-low temperature materials useful for the treatment and/or prevention of disease. The present disclosure also provides packaging materials, methods of transportation, and methods of storage for maintaining biological and/or pharmaceutical materials at ultra-low temperatures in order to maintain the integrity of the materials. The present disclosure further relates to the field of RNA to prevent or treat coronavirus infection.

Abstract: In a bulk package system the stack of plates having a height Hplate is contacted and stabilized by an internal packaging structure with a height Hint which is higher than the stack to aid in protection of the plates from forces from above. A separate external packaging structure is provided with a height Hext being equal or larger than Hint. Forces acting upon the external packaging structure caused by e.g., collisions are not transferred to the stack of plates. The external packaging structure is assembled after the internal packaging structure.