Abstract: The application relates to a method for producing a moulded part assembly from a first plastic moulded part and a second plastic moulded part by means of laser welding, wherein the first plastic moulded part consists at least partially of a first material and the second plastic moulded part consists at least partially of a second material that can be welded to the first material, wherein a welding region of the second plastic moulded part is arranged in a stepped receiving means of the first plastic moulded part, or vice versa. According to the invention, during the laser welding, the first plastic moulded part and the second plastic moulded part are to be shifted onto one another in a shifting direction. The invention also relates to a production device for producing a moulded part assembly.

Abstract: The present invention relates to a controlled-release oral dosage form for administration of oxycodone once a day and a method of preparing a controlled-release oral dosage form for administration of oxycodone once a day.

Abstract: A plug-in connector for detachably connecting two lines has a first connector element, a second connector element, a carrier element to be fixed to the first connector element, and a latching element with at least one latching arm. The latching arm is disposed on the carrier element and when it is in a latching position, latches onto a matching latching element of the second connector element. The latching element is axially displaceable to assume a latching arm securing position and a latching arm release position relative to the carrier element. An operating element is provided on the carrier element for actuation in the latching arm release position to displace the latching arm into a separating position and which, when actuated in the latching arm securing position, retains the latching element in the latching arm securing position.

Abstract: The present invention relates to a controlled-release oral dosage form for administration of oxycodone once a day and a method of preparing a controlled-release oral dosage form for administration of oxycodone once a day.

Abstract: This invention relates to a oral pharmaceutical formulation for methylphenidate or its analogs, derivatives, isomers or enantiomers, including d-threo-methylphenidate.

Abstract: A pipe system for the conducting of highly flammable liquids and method for making the pipe system. The pipe system includes at least one tubular conducting element having an inner pipe and an outer casing surrounding the inner pipe. The inner pipe and the outer casing respectively include a plastic, and the outer casing has a flame protection durability of 3 minutes at 600° C. and of 2 minutes at 800° C.

Abstract: A pipe connection system and method of forming the pipe connection system. The pipe connection system includes at least one tubular conducting element including an inner pipe and an outer casing and at least one coupling element including an inner component and a coating. The at least one tubular conducting element and the at least one coupling element respectively include plastic and are connected to one another. Further, the coating is welded to the outer casing and the inner pipe is welded to the inner component.

Abstract: This invention relates to a oral pharmaceutical formulation for methylphenidate or its analogs, derivatives, isomers or enantiomers, including d-threo-methylphenidate.

Abstract: A plug-in connector for detachably connecting two lines has a first connector element, a second connector element, a carrier element to be fixed to the first connector element, and a latching element with at least one latching arm. The latching arm is disposed on the carrier element and when it is in a latching position, latches onto a matching latching element of the second connector element. The latching element is axially displaceable to assume a latching arm securing position and a latching arm release position relative to the carrier element. An operating element is provided on the carrier element for actuation in the latching arm release position to displace the latching arm into a separating position and which, when actuated in the latching arm securing position, retains the latching element in the latching arm securing position.

Abstract: Push fit coupling and method for connecting two fluid lines. The coupling includes a first element having a plug-in opening, a second element insertable into the plug-in opening, a retaining device for detachably holding the first and second elements together, and a valve, insertable into the plug-in opening, located on a front face of the second element.

Abstract: A valve (49) which is intended for insertion into the line connecting a fuel pump to a system of injection valves and which is designed as a pressure-maintaining valve is characterized by a pipe body (50) intended to have a flow passing through it, into which a sleeve (53) is inserted which forms a damping cylinder (55) in a middle region, inside which damping cylinder one end of a blocking body (57) is received so as to be able to slide in the direction of the axis (58) of the pipe body (50). The opposite end of the blocking body (57) is characterized by a sealing body (67) which is formed from an elastomeric material and which cooperates with a valve seat (66) which is allocated a through bore (65) in a transverse wall (63) of the pipe body (50). The blocking body (57) lies against this valve seat under resilient pretensioning and the movement of the blocking body is damped or is accompanied by the lowest possible noise development by reason of the cooperation with the damping cylinder.

Abstract: A valve (49) which is intended for insertion into the line connecting a fuel pump to a system of injection valves and which is designed as a pressure-maintaining valve is characterized by a pipe body (50) intended to have a flow passing through it, into which a sleeve (53) is inserted which forms a damping cylinder (55) in a middle region, inside which damping cylinder one end of a blocking body (57) is received so as to be able to slide in the direction of the axis (58) of the pipe body (50). The opposite end of the blocking body (57) is characterized by a sealing body (67) which is formed from an elastomeric material and which cooperates with a valve seat (66) which is allocated a through bore (65) in a transverse wall (63) of the pipe body (50). The blocking body (57) lies against this valve seat under resilient pretensioning and the movement of the blocking body is damped or is accompanied by the lowest possible noise development by reason of the cooperation with the damping cylinder.

Abstract: A monolithic composition includes alfuzosin in a polymeric matrix adapted to release 13-33% of the alfuzosin within 2 hours, 40-60% of the alfuzosin within 7 hours, and greater than 80% of the alfuzosin within 20 hours of administration. A unit dosage form includes: a heterogeneous mixture of alfuzosin hydrochloride anhydrate, lactose monohydrate, hydroxypropylmethylcellulose, polyvinylpyrrolidone and magnesium stearate, wherein the heterogeneous mixture is heterogeneously distributed throughout the unit dosage form. A manufacturing process includes: mixing a hydrophilic polymer and alfuzosin to provide a blend; granulating the blend to provide granules; drying the granules on a dryer to provide dried granules; sizing the dried granules to provide sized granules; mixing the sized granules with a lubricant to obtain a mixture; and compressing the mixture to obtain a tablet. A method of treating benign prostatic hyperplasia, includes administering to a patient the composition or unit dosage form once a day.