Abstract: A method of applying a pattern of metal, metal oxide, and/or semiconductor material on a substrate, a pattern created by that method, and uses of that pattern.

Abstract: The invention relates to a method of 13C-MR imaging, 13C-MR spectroscopy and/or 13C-MR spectroscopic imaging of inflammation or infection using an imaging medium which comprises a hyperpolarized 13C-substance.

Abstract: The present invention relates to a force measuring device comprising an amorphous carbon layer which is disposed on a solid actuator and has piezoresistive properties.

Abstract: The invention is a device and a method for eliminating vibrations of a mechanical structure with at least one electromechanical converter material that is actively connected to the mechanical structure and connected to an electrical circuit with at least one electrical impedance. The electrical circuit is connected to an interface, via which the at least one electrical impedance can be variably adjusted by wireless or wired communications with a control unit that is separated from the electrical circuit in which the electrical impedance features at least one variable ohmic resistor, inductive resistor or capacitor.

Abstract: A method of registering biomedical images to reduce imaging artifacts caused by object movement is disclosed, wherein a certain number of features or landmarks is automatically defined and tracked in a first and second image to be registered to determine the optical flow vector between the first and second image. Registration then takes place by applying the inverse optical flow to the second image. The automatic feature selection step is carried out by determining the mean signal intensity in a defined neighborhood for every pixel, which mean signal intensity is then compared to a predetermined threshold. If the mean signal intensity value of said neighborhood is higher than the predetermined threshold the pixel is defined as a feature and is added to a list of features to be tracked.

Abstract: A method of applying a pattern of metal, metal oxide, and/or semiconductor material on a substrate, a pattern created by that method, and uses of that pattern.

Abstract: A method of applying material on a substrate. The material to be applied can be a pattern of material.

Abstract: The invention is a device for influencing the vibration of a planar element having two opposite surfaces and a neutral fiber plane running between the two surfaces including at least one actuator and at least one sensor which each are provided with transducer materials and are connected to at least one electronic component or an electronic module. The at least one actuator and at least one sensor are completely integrated into the planar element so as to be spaced from the two surfaces as well as from the neutral fiber plane.

Abstract: The present invention relates to a method of patterning molecules on a substrate using a micro-contact printing process, to a substrate produced by said method and to uses of said substrate. It also relates to a device for performing the method according to the present invention.

Abstract: A method and associated substrate is provided for applying a layer or pattern of metal on a substrate. The method includes providing a target substrate, immobilizing a layer of polymeric material on the target substrate, and applying and immobilizing a layer or pattern of metal on the layer of polymeric material on the target substrate using a stamp onto which the layer or pattern of metal has previously been applied, by bringing the stamp into conformal contact with the target substrate.

Abstract: The present invention relates to a method of patterning molecules on a substrate using a micro-contact printing process, to a substrate produced by said method and to uses of said substrate. It also relates to a device for performing the method according to the present invention.

Abstract: Magnetic resonance imaging (MRI) is enhanced by contrast agents such as superparamagnetic iron-oxide (SPIO) particles that resemble magnetite particles produced by magnetotactic bacteria. Magnetospirillum magneticum AMB-1 produces positive MRI contrast when generating ultrasmall magnetite particles (10-40 nm diameter). Positive MRI contrast permits clearer distinction from image voids compared to negative contrast. T1-weighted MRI showed that such bacteria increased positive contrast 2.2-fold (p<0.02) in vitro and 2.0-fold (p<0.02) following intratumoral injection in mouse tumor xenografts. Upon intravenous delivery, Magnetospirillum magneticum AMB-1 targeted tumors and generated increased positive MRI contrast in them (1.4-fold; p<0.01). AMB-1 tumor targeting was shown by viable counts, microPET imaging of radio-labeled AMB-1, and Prussian blue staining of tumor sections. Thus, magnetotactic bacteria provide a tool for improving cancer diagnosis and monitoring treatment response by MRI.

Abstract: A method of imaging the individual components of systems with sparse spectra using magnetic resonance imaging including the steps of a) exciting nuclei of labeled components using a MRI pulse sequence, b) selecting a proper spectral window to avoid/minimize signal overlap of aliased frequency components. In step a) preferably a spiral chemical shift imaging (spCSI) sequence is employed. In a preferred embodiment, hyperpolarized nuclei of 13C are used for labeling in a pyruvate substrate with metabolites of lacatate, alanine, and bicarbonate.

Abstract: A device is described for vibration damping, which is attachable on a mechanical structure or integratable therein, having at least one mass which is indirectly or directly operationally linked to the structure via elastic means, referred to as the so-called damper mass, and at least one actuator for changing a stiffness which can be associated with the elastic means. The invention provides an electrical power source, which is capable of generating electrical power exclusively using an oscillating relative movement resulting along the operational link between the damper mass and the structure, and a regulating unit, which is connected to the electrical power source, which activates the at least one actuator as a function of the vibration behavior of the structure based upon a vibration damping rule.

Abstract: What is described is an oscillation decoupling device with a load-receiving element which is mounted in an oscillating manner relative to a support unit at least along an active direction along which at least part of the load is applied, and with at least one sensor-actuator unit which detects an oscillation of the element due to the load and acts against the oscillation of the element by means of actuators. The invention is characterised in that the support unit is modularly configured and serves as a support structure for at least one unit that receives the element and is elastically deformable in the active direction of the load, in that the load-receiving element is connected to the elastically deformable unit, and in that an actuator influencing the deformation is applied to the at least one unit, or is integrated in it, so that the actuator initiates a deformation acting against an elastic deformation due to the load inside the unit.

Abstract: A method of applying material on a substrate. The material to be applied can be a pattern of material.

Abstract: The invention describes a device as well as a method for eliminating vibrations of a mechanical structure with at least one electromechanical converter material that is actively connected to the mechanical structure and connected to an electric circuit arrangement with at least one electrical impedance. The invention is characterized in that the electric circuit is connected to an interface, via which the at least one electrical impedance can be variably adjusted by means of wireless or wired communication with a control unit that is separated from the electronic circuit arrangement, and in that the electrical impedance features at least one ohmic resistor and/or one inductive resistor and/or one capacitor that are respectively realized variably.

Abstract: A method of registering biomedical images to reduce imaging artefacts caused by object movement is disclosed, wherein a certain number of features or landmarks is automatically defined and tracked in a first and second image to be registered to determine the optical flow vector between the first and second image. Registration then takes place by applying the inverse optical flow to the second image. The automatic feature selection step is carried out by determining the mean signal intensity in a defined neighborhood for every pixel, which mean signal intensity is then compared to a predetermined threshold. If the mean signal intensity value of said neighborhood is higher than the predetermined threshold the pixel is defined as a feature and is added to a list of features to be tracked.

Abstract: The invention is a device for influencing the vibration of a planar element having two opposite surfaces and a neutral fiber plane running between the two surfaces including at least one actuator and at least one sensor which each are provided with transducer materials and are connected to at least one electronic component or an electronic module. The at least one actuator and at least one sensor are completely integrated in the planar element to be spaced from the two surfaces as well as from the neutral fiber plane.

Abstract: A method and associated substrate is provided for applying a layer or pattern of metal on a substrate. The method includes providing a target substrate, immobilizing a layer of polymeric material on the target substrate, and applying and immobilizing a layer or pattern of metal on the layer of polymeric material on the target substrate using a stamp onto which the layer or pattern of metal has previously been applied, by bringing the stamp into conformal contact with the target substrate.