Abstract: The present invention relates compounds of the formula A oligosaccharide-spacer-GpIIb/IIIa antagonist ??(A). The compounds of the invention have antithrombotic activity and can be used in treating or preventing thrombotic diseases.

Abstract: The present invention provides a joint (6) between insulated pipes (4), which comprises: (a) two transport pipes joined together; (b) insulation on each transport pipe which ends short of the joint; (c) a casing surrounding the exposed portion of pipe; (d) a sleeve which provides a seal between an end of the casing and the adjacent pipe insulation, wherein the sleeve comprises recoverable polymeric material (1) coated at discrete regions with a sealant (3) and/or a heat-activatable adhesive (2), (preferably with the sealant (3) bridging the end of the casing and the pipe insulation to form a seal therebetween which can accommodate movement of the casing relative to the pipe insulation, and the adhesive (2) forming substantially annular bonds between the sleeve and the casing and between the sleeve and pipe insulation), characterised in that at least one region (4) of the sleeve, preferably between the sealant-coated and the adhesive-coated regions or at the edge of the sleeve, remains uncoated to provide a re