Patents by Inventor Dirk Moritz

Dirk Moritz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bifunctional protein, preparation and use
    Patent number: 6984382
    Abstract: A bifunctional protein comprising: 1) a single-chain antibody directed against a suitable antigen on a tumour cell, 2) a hinge region comprising from about 40 to about 200 amino acids joined to the VL domain of the single chain antibody, and 3) a functional zeta (?) chain from the T-cell antigen receptor (TCR) joined to the hinge region, wherein the hinge region is an immunoglobin-like hinge region which is joined to the C-terminus of the VL domain of the single-chain antibody. The functional zeta (?) chain comprises the transmembrane and the cytoplasmic domain. The bifunctional protein can be expressed using a cytotoxic lymphocyte (CTL) expressing DNA encoding it.
    Type: Grant
    Filed: June 19, 2000
    Date of Patent: January 10, 2006
    Inventors: Bernd Groner, Dirk Moritz