Abstract: A method includes the step of obtaining respective impurity levels of at least one impurity in each raw material of a plurality of raw materials. The method includes the step of obtaining a formulation of a cell culture medium. The formulation indicates a ratio of the plurality of raw materials in the cell culture medium. The method includes the step of determining, at least partially based on the formulation and on the respective impurity levels, a total impurity level of the at least one impurity in the cell culture medium.

Abstract: Systems and methods for using a simulation model to assess compliance of a product having a design that extends beyond a validation space of the simulation model are provided. According to certain aspects, systems and methods may verify and validate a simulation model associated with a product and with a given validation space. The systems and methods may assess compliance, with a standard, of a product that extends beyond the validation space by calculating a correlation factor based on characteristics product designs, and using the correlation factor with the verified and validated simulation model.

Abstract: Systems and methods for employing physical and virtual testing of products to assess compliance with standards are provided. According to certain aspects, a physical testing machine may perform a physical test of a physical product. Additionally, an electronic device may perform multiple virtual tests of multiple virtual versions of the physical product based on an output of the physical test as well as an applicable standard. Based on the results of the virtual tests, the electronic device may determine whether to certify a physical version of one of the virtual versions of the physical product according to the applicable standard.

Abstract: A wiping system for a robotic repair unit is presented that includes a motive robot arm with a motor, a connection mechanism coupled to the motive robot arm, and a wiping medium coupled to the connection mechanism. The wiping medium includes a base layer and a plurality of features extending from the base layer. The motive robot arm, powered by the motor, moves the wiping medium. The motive robot arm is configured to move the wiping medium toward, or away from, a worksurface. The motive arm is configured to press the wiping medium toward the worksurface during a wiping operation. During the wiping operation, the wiping medium is driven by a wiping motor against the surface.

Abstract: A vehicle door handle assembly with a sensor device for detecting an actuation is provided. A handle of the handle assembly has a section which can be gripped from behind and an outer wall that delimits an interior in which an electronic sensor device is arranged and fixed. The handle section is formed with a reduced outer wall thickness in an actuation region and has a deformability that is increased with respect to the remaining sections of the handle. The outer wall thickness is reduced solely on the outer wall face oriented towards the interior. The handle outer wall inner face oriented towards the interior is coated with a metal layer at least in the actuation region. The electronic sensor device comprises at least one inductive distance sensor which lies opposite the metal layer in the interior of the handle to detect a deformation of the opposing outer wall.

Abstract: A method for processing tobacco includes providing a first tube having at least one inlet and at least one outlet and having a shape of a helix having a plurality of threads, providing a first motor, generating vibrations, transmitting the vibrations to the first tube, inserting an amount of tobacco, having a first moisture content, into the inlet of the first tube, providing a first air flow through the first tube in a direction from the inlet to the outlet, transporting the amount of tobacco within the first tube towards the outlet of the first tube by the vibrations transmitted to the first tube and by the first air flow, taking out the tobacco at the outlet of the first tube, the tobacco having a second moisture content which is lower than the first moisture content.

Abstract: Surprisingly, it was found that zeolites can be used to decrease the concentration of inorganic ions, such as calcium ions, from a body fluid, such as plasma, in sufficient way. Such decrease of the concentration of inorganic ions, such as calcium ions, was found to lead to an inhibition of hemostasis including an inhibition of coagulation, especially inhibiting the activation of factor VII and the formation of fibrin.

Abstract: A vehicle door handle with a handle component is provided. The handle component includes a hollow body, and an inductive sensor device is arranged in a cavity in order to detect an actuation of the handle component. A support having a support fastening section and a self-supporting section connected to the latter are arranged in the cavity, wherein the support fastening section is secured to the vehicle door handle, and wherein the self-supporting section of the support extends in the interior of the cavity at a distance from the wall surfaces of the handle component such that the self-supporting section of the support is mechanically decoupled from the wall surfaces of the handle component. The inductive sensor device is held in the self-supporting section, wherein a metallic material is arranged in at least one section of those wall surfaces of the handle component which surround the self-supporting section.

Abstract: A door handle assembly for a motor vehicle includes a handle carrier mounted on the vehicle and a grip part rotatably mounted on the handle carrier. The grip part opens a door or flap of the motor vehicle. A coupling device is rotatably mounted on the handle carrier for transmitting an actuation of the grip part to a locking arrangement on the vehicle. A joint element pivotably interconnects the coupling device and the grip part. The joint element movably supports an actuating member which is moved by rotation translationally between mounting and operating positions. In the operating position, the actuating member is pivotably mounted on the coupling device and is in engagement with the grip part. In the mounting position, the actuating member bears against a blocking surface of the coupling device that blocks rotation of the actuating member and is out of engagement with the grip part.

Abstract: A lock system for a motor vehicle includes a handle for opening a door or hatch, a drive device coupled to the handle, and a control device which is suited for checking an access code of a mobile ID transmitter, coupled to the drive device. A lock device is provided for the door or hatch. The handle can move between a non-use position in which it is flush with an outer contour of the door or hatch and an opening position in which it protrudes at least in part from the outer contour. The drive device is coupled and designed for opening or closing the door or hatch such that it moves along a movement path along which the drive device extends the handle into its opening position or retracts it into its non-use position, as well as actuating the lock device.

Abstract: A method of producing wood-base panels, especially OSB wood-base panels is provided. The method including the steps of providing wood strands, applying at least one adhesive system to the wood strands having at least one polymer adhesive and at least one nanoparticle below 500 nm, and pressing the wood strands admixed with the adhesive system to form wood-base panels.

Abstract: The present disclosure relates to methods, processing systems and computer program products of global routing of integrated circuits based on localized routing optimization. In certain embodiments, the method may include one or more of: defining one or more regions, one or more netgroups, and combinations thereof of an integrated circuit, associating at least one optimization objective with each region and/or each netgroup defined, generating one or more constraints for each region and/or each netgroup based on the associated optimization objectives, and performing global routing of the integrated circuit according to the one or more constraints.

Abstract: vehicle door handle assembly with a sensor device for detecting an actuation is provided. A handle of the handle assembly has a section which can be gripped from behind and an outer wall that delimits an interior in which an electronic sensor device is arranged and fixed. The handle section is formed with a reduced outer wall thickness in an actuation region and has a deformability that is increased with respect to the remaining sections of the handle. The outer wall thickness is reduced solely on the outer wall face oriented towards the interior. The handle outer wall inner face oriented towards the interior is coated with a metal layer at least in the actuation region. The electronic sensor device comprises at least one inductive distance sensor which lies opposite the metal layer in the interior of the handle to detect a deformation of the opposing outer wall.

Abstract: A vehicle door handle with a handle component is provided. The handle component includes a hollow body, and an inductive sensor device is arranged in a cavity in order to detect an actuation of the handle component. A support having a support fastening section and a self-supporting section connected to the latter are arranged in the cavity, wherein the support fastening section is secured to the vehicle door handle, and wherein the self-supporting section of the support extends in the interior of the cavity at a distance from the wall surfaces of the handle component such that the self-supporting section of the support is mechanically decoupled from the wall surfaces of the handle component. The inductive sensor device is held in the self-supporting section, wherein a metallic material is arranged in at least one section of those wall surfaces of the handle component which surround the self-supporting section.

Abstract: A lock system for a motor vehicle includes a handle for opening a door or hatch, a drive device coupled to the handle, and a control device which is suited for checking an access code of a mobile ID transmitter, coupled to the drive device. A lock device is provided for the door or hatch. The handle can move between a non-use position in which it is flush with an outer contour of the door or hatch and an opening position in which it protrudes at least in part from the outer contour. The drive device is coupled and designed for opening or closing the door or hatch such that it moves along a movement path along which the drive device extends the handle into its opening position or retracts it into its non-use position, as well as actuating the lock device.

Abstract: The present invention relates to the purification of target molecules like immunoglobulins from plasma. The use of a certain type of ion exchanger based on a crosslinked polyvinylether results in especially high yields of the target molecule.

Abstract: The present disclosure relates to methods, processing systems and computer program products of global routing of integrated circuits based on localized routing optimization. In certain embodiments, the method may include one or more of: defining one or more regions, one or more netgroups, and combinations thereof of an integrated circuit, associating at least one optimization objective with each region and/or each netgroup defined, generating one or more constraints for each region and/or each netgroup based on the associated optimization objectives, and performing global routing of the integrated circuit according to the one or more constraints.

Abstract: A method of producing wood-base panels, especially OSB wood-base panels is provided. The method including the steps of providing wood strands, applying at least one adhesive system to the wood strands having at least one polymer adhesive and at least one nanoparticle below 500 nm, and pressing the wood strands admixed with the adhesive system to form wood-base panels.

Abstract: Actuating handle (100) for a motor vehicle for opening and/or closing a door or a flap, comprising a grip element (101) which is designed for movement between an actuating position, in which the grip element (101) is arranged that can be actuated for manually opening a door or a flap (103), and a locking position, in which the grip element (101) is accommodated in a recess (105), wherein the grip element (101) comprises surrounding grip element delimiting sections (107) and the recess (105) has recess delimiting sections (109), wherein the actuating handle (100) is designed such that in the locking position of the grip element (101) each of the grip element delimiting sections (107) is arranged opposite a corresponding recess delimiting section (109), and wherein lighting means (201) are arranged at least in some regions on the grip element delimiting sections (107).

Abstract: A two-phase system containing at least one solvatochromic dye, water, at least one fragrance, and at least one solvent. Wherein the two-phase system includes liquid phases layered one on top of the other. The inventive compositions can be used as exhaustion indicators for fragrance release systems.