Abstract: Disclosed herein is a CPAP device. In some embodiments, the CPAP device may be a bCPAP device. In some embodiments, the device may have one or more features that may assist in heating efficiency. In some embodiments, an air mixture is sent to a humidifier via an inlet conduit prior to introduction to a patient. In some embodiments, a water chamber of the humidifier may be recessed within a compartment. In some embodiments, waste heat from one or more components of the device may be used to pre-heat the air mixture in the inlet conduit.

Abstract: A microfluidic device for evaluation of test subjects for induced neural injury performs testing of multiple test subjects based on uniform and repeatable test stimuli for evaluating neural response for research including traumatic brain injury. A microfluidic device contains multiple test subjects and delivers a consistent, measured test stimuli simulating TBI to each of the test subjects simultaneously. The result is a system to assess neural function, behavior, and neural structure of small animals responsive to sonication-induced traumatic brain injury, to investigate risk and potential recovery. The microfluidic device disposes test subjects at a uniform distance from an injury inducing surface that emits sonication energy to simulate TBI. The uniform distance ensures that each test subject receives the same, controlled injury stimuli, and the test subjects may be evaluated with an attached microscope or video input, or may be extracted from the microfluidic device for further evaluation.

Abstract: Provided are methods of the production of patterned 3-dimensional biopolymer scaffolds containing living cells. The methods include selective photopolymerization of biopolymers to create patterned structures and the patterning of cells within relatively homogenous slabs of biopolymer using dielectrophoresis. Also provided are patterned 3-dimensional biopolymer scaffolds generated by the methods and their use.