Patents by Inventor Dirk-Rolf Gieselmann

Dirk-Rolf Gieselmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11378579
    Abstract: The present invention relates to a novel MMP-8 activation product such as a MMP-8 middle-part activation product. The invention also relates to detecting such a MMP-8 activation product or activated MMP-8 fragments in a biological sample derived from a subject and to the use thereof for diagnosing diseases which relate to abnormal or elevated levels of activated MMP-8.
    Type: Grant
    Filed: May 2, 2019
    Date of Patent: July 5, 2022
    Assignees: Oy Medix Biochemica AB, Dentognostics GmbH
    Inventors: Timo Sorsa, Dirk-Rolf Gieselmann, Armi Korvuo, Kurt Maier, Païvi Mäntylä, Ismo Råman, Sinikka Tiisala
  • Publication number: 20200064346
    Abstract: The present invention relates to a novel MMP-8 activation product such as a MMP-8 middle-part activation product. The invention also relates to detecting such a MMP-8 activation product or activated MMP-8 fragments in a biological sample derived from a subject and to the use thereof for diagnosing diseases which relate to abnormal or elevated levels of activated MMP-8.
    Type: Application
    Filed: May 2, 2019
    Publication date: February 27, 2020
    Inventors: Timo SORSA, DIRK-ROLF GIESELMANN, ARMI KORVUO, KURT MAIER, PÄIVI MÄNTYLÄ, ISMO RÅMAN, SINIKKA TIISALA
  • Patent number: 10488415
    Abstract: MMP-8 activation products are disclosed that have a MMP-8 middle-part activation product having a size between 20-35 kDa. Methods of detecting the MMP-8 activation product or activated MMP-8 fragments in a biological sample derived from a subject are also disclosed. The MMP-8 activation product or activated MMP-8 fragments diagnose diseases based on abnormal or elevated levels of activated MMP-8.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: November 26, 2019
    Assignees: OY MEDIX BIOCHEMICA AB, DENTOGNOSTICS GMBH
    Inventors: Timo Sorsa, Dirk-Rolf Gieselmann, Armi Korvuo, Kurt Maier, Päivi Mäntylä, Ismo Råman, Sinikka Tiisala
  • Patent number: 10330681
    Abstract: MMP-8 activation products are disclosed that have a MMP-8 middle-part activation product having a size between 20-35 kDa. Methods of detecting the MMP-8 activation product or activated MMP-8 fragments in a biological sample derived from a subject are also disclosed. The MMP-8 activation product or activated MMP-8 fragments diagnose diseases based on abnormal or elevated levels of activated MMP-8.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: June 25, 2019
    Assignees: OY MEDIX BIOCHEMICA AB, DENTOGNOSTICS GMBH
    Inventors: Timo Sorsa, Dirk-Rolf Gieselmann, Armi Korvuo, Kurt Maier, Päivi Mäntylä, Ismo Råman, Sinikka Tiisala
  • Publication number: 20180250101
    Abstract: An implant, in particular for anchoring dental prostheses, has a zirconium nitride (ZrN) coating covering in particular in the sections that come into contact with the soft tissue.
    Type: Application
    Filed: May 7, 2018
    Publication date: September 6, 2018
    Inventors: Dirk-Rolf Gieselmann, Harald Ceschinski
  • Publication number: 20170023571
    Abstract: MMP-8 activation products are disclosed that have a MMP-8 middle-part activation product having a size between 20-35 kDa. Methods of detecting the MMP-8 activation product or activated MMP-8 fragments in a biological sample derived from a subject are also disclosed. The MMP-8 activation product or activated MMP-8 fragments diagnose diseases based on abnormal or elevated levels of activated MMP-8.
    Type: Application
    Filed: February 27, 2015
    Publication date: January 26, 2017
    Inventors: Timo SORSA, Dirk-Rolf GIESELMANN, Armi KORVUO, Kurt MAIER, Päivi MÄNTYLÄ, Ismo RÅMAN, Sinikka TIISALA
  • Publication number: 20150272707
    Abstract: An implant, in particular for anchoring dental prostheses, has a zirconium nitride (ZrN) coating covering in particular in the sections that come into contact with the soft tissue.
    Type: Application
    Filed: June 15, 2015
    Publication date: October 1, 2015
    Inventors: Dirk-Rolf Gieselmann, Harald Ceschinski
  • Patent number: 8979533
    Abstract: The invention relates to an implant for anchoring a prosthesis in the jaw of a patient, having a base body (1) and a post (2) connecting to the top thereof, wherein the post (2) engages with a recess opening (3) of the base body (1) in a positive and non-positive manner and can be firmly connected thereto. In order to improve such an implant, the invention suggests that a sealing collar (4) surrounding the recess opening (3), and an annular groove (5) surrounding the sealing collar (4) be provided on the top of the base body (1), wherein the post (2) has a circumferential shoulder (6) on the bottom thereof facing the base body (1), the shoulder having a shape that is complementary to the sealing collar (4) and the annular groove (5).
    Type: Grant
    Filed: March 15, 2008
    Date of Patent: March 17, 2015
    Assignee: MDI Dental—Und Implantattechnik GmbH
    Inventors: Dirk-Rolf Gieselmann, Harald Ceschinski
  • Publication number: 20110053115
    Abstract: The invention relates to an implant for anchoring a prosthesis in the jaw of a patient, having a base body (1) and a post (2) connecting to the top thereof, wherein the post (2) engages with a recess opening (3) of the base body (1) in a positive and non-positive manner and can be firmly connected thereto. In order to improve such an implant, the invention suggests that a sealing collar (4) surrounding the recess opening (3), and an annular groove (5) surrounding the sealing collar (4) be provided on the top of the base body (1), wherein the post (2) has a circumferential shoulder (6) on the bottom thereof facing the base body (1), the shoulder having a shape that is complementary to the sealing collar (4) and the annular groove (5).
    Type: Application
    Filed: March 15, 2008
    Publication date: March 3, 2011
    Inventors: Dirk-Rolf Gieselmann, Harald Ceschinski
  • Publication number: 20100086896
    Abstract: The invention relates to an implant, in particular for anchoring dental prostheses, which is provided with a zirconium nitride (ZrN) coating and/or a zirconium oxide (ZrO2) coating covering in particular the sections that come into contact with the soft tissue.
    Type: Application
    Filed: July 20, 2007
    Publication date: April 8, 2010
    Inventors: Dirk-Rolf Gieselmann, Harald Ceschinski