Abstract: Methods, systems and computer program products for estimating the gestational age of a fetus are provided. According to one embodiment, the method generates a component image from a segmented ultrasound image of a fetal head. The component image includes one or more edges. The method then identifies a third ventricle within the component image. The method estimates a length of a bi-parietal diameter, based at least in part on the orientation of the third ventricle. Thereafter, the method estimates the gestational age of the fetus.

Abstract: The invention relates to a computer implemented method and systems for cell level fish dot counting. FISH (fluorescence in situ hybridization) dot counting is the process of enumerating chromosomal abnormalities in the cells which can be used in areas of diagnosis and cancer research. The method comprises in part overlaying images of a biological sample comprising a nuclear counterstain mask and a FISH binary mask. The FISH binary mask is extracted using a multi-level extended h-maxima or h-minima.

Abstract: A method for automatically measuring interventricular septum thickness is provided. The method in one embodiment comprises acquiring a series of ultrasound images of a heart, acquiring a septum mask by applying a septum segmentation algorithm on the series of ultrasound images, localizing a mitral valve tip using a valve tip localization algorithm and calculating the thickness of the interventricular septum using an interventricular septum thickness algorithm. The interventricular septum thickness algorithm uses the septum mask and the localized mitral valve tip as inputs.

Abstract: Systems and methods for segmenting images comprising cells, wherein the images comprise a plurality of pixels; one or more three dimensional (3D) clusters of cells are identified in the images; and the 3D clusters of cells are automatically segmented into individual cells using one or more models.

Abstract: Systems and methods for extracting information about an organism of interest, such as an atlas of the organism of interest; a storage device for at least temporarily storing an image of the organism of interest; and an operating device that automatically creates a map of the image of the organism of interest and automatically compares the map of the image to the atlas of the organism.

Abstract: The present techniques provide for the evaluation of cellular motion and/or cellular properties based on an analysis of motion for cluster of cells. In an exemplary technique, images of cells are acquired and the image is segmented into clusters. Motion data for each respective cluster is derived from the segmented data. The properties of each cluster can be used to evaluate cellular properties and/or cellular motion properties.

Abstract: Methods, systems and computer program products for estimating the gestational age of a fetus are provided. According to one embodiment, the method generates a component image from a segmented ultrasound image of a fetal head. The component image includes one or more edges. The method then identifies a third ventricle within the component image. The method estimates a length of a bi-parietal diameter, based at least in part on the orientation of the third ventricle. Thereafter, the method estimates the gestational age of the fetus.

Abstract: An imaging system for generating three-dimensional (3D) images includes an imaging probe for acquiring two-dimensional (2D) image data of a region of interest. A sensor is coupled with the imaging probe to determine positional data related to a position of the imaging probe. A position determination module utilizes the image data acquired with the imaging probe and the positional data determined by the sensor to calculate a probe location with respect to the acquired 2D image data. An imaging module is configured to reconstruct a 3D image of the region of interest based on the 2D image data and the determined probe locations.

Abstract: A method for automatically measuring interventricular septum thickness is provided. The method in one embodiment comprises acquiring a series of ultrasound images of a heart, acquiring a septum mask by applying a septum segmentation algorithm on the series of ultrasound images, localizing a mitral valve tip using a valve tip localization algorithm and calculating the thickness of the interventricular septum using an interventricular septum thickness algorithm. The interventricular septum thickness algorithm uses the septum mask and the localized mitral valve tip as inputs.

Abstract: The present techniques provide for the processing of color tissue images based on image segmentation. In an exemplary embodiment, the color and texture features of pixels in a tissue image are used to generate a matrix of feature vectors. A subset of feature vectors is selected from the matrix of feature vectors and a set of colors and textures are derived using the tissue image and the subset of feature vectors. An initial segmented tissue image is then generated from this set of colors and textures.

Abstract: The present invention provides a cell imaging technique for automatically tracking the progression of a cell through the cell cycle over time through segmentation of a volume of two-dimensional time-lapse images. The technique allows long-term tracking of the cell cycle progression of an individual cell or multiple cells. Further, the invention provides a unique display of cell cycle progression, allowing an end user to easily determine changes to cell cycle progression for a cell of interest.

Abstract: Systems and methods for extracting information about an organism of interest, generally comprising, an atlas of the organism of interest; a storage device for at least temporarily storing an image of the organism of interest; and an operating device that automatically creates a map of the image of the organism of interest and automatically compares the map of the image to the atlas of the organism.

Abstract: Systems and methods for segmenting images comprising cells, wherein the images comprise a plurality of pixels; one or more three dimensional (3D) clusters of cells are identified in the images; and the 3D clusters of cells are automatically segmented into individual cells using one or more models.

Abstract: The present techniques provide for the processing of color tissue images based on image segmentation. In an exemplary embodiment, the color and texture features of pixels in a tissue image are used to generate a matrix of feature vectors. A subset of feature vectors is selected from the matrix of feature vectors and a set of colors and textures are derived using the tissue image and the subset of feature vectors. An initial segmented tissue image is then generated from this set of colors and textures.

Abstract: An imaging system for correcting a bias in the location edges in an image is provided. The imaging system comprises an image processor configured to detect edges in an image of a given substructure, characterize a blurring factor in the image and correct a bias in the detected edges in the of a given substructure using the blurring factor.