Patents by Inventor Dirk Schnappinger

Dirk Schnappinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CONDITIONALLY REPLICATING M. BOVIS BCG
    Publication number: 20230039352
    Abstract: Conditionally replicating recombinant cells, compositions and vaccines having the cells, and methods of using the cells, are provided.
    Type: Application
    Filed: January 8, 2021
    Publication date: February 9, 2023
    Inventors: Dirk Schnappinger, Sabine Ehrt
  • Tetracycline regulated transcriptional modulators with altered DNA binding specificities
    Patent number: 5589362
    Abstract: Isolated nucleic acid molecules encoding fusion proteins which regulate transcription in eukaryotic cells are disclosed. The fusion proteins of the invention comprise a Tet repressor having at least one amino acid mutation that confers on the fusion protein an ability to bind a class B tet operator sequence having a nucleotide substitution at position +4 or +6, operatively linked to a polypeptide which regulates transcription in eukaryotic cells. Methods for regulating transcription of a tet operator-linked gene in a cell are also provided.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 31, 1996
    Assignees: BASF Aktiengesellschaft, Knoll Aktiengesellschaft
    Inventors: Hermann Bujard, Manfred Gossen, Wolfgang Hillen, Vera Helbl, Dirk Schnappinger