Patents by Inventor Dirk Spickermann

Dirk Spickermann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODIFIED RELEASE FORMULATION
    Publication number: 20230355582
    Abstract: Drug products in the form of modified release formulations comprising the drug substance (-)-(3aR,45,7aR)-4-Hydroxy-4m-tolylethynyl-octahydro-indole-1-carboxylic acid methyl ester (AFQ056), as well as processes for making such drug products are provided. The drug products are useful in treating patients with Parkinson's disease and exhibiting L-dopa induced dyskinesia.
    Type: Application
    Filed: July 20, 2023
    Publication date: November 9, 2023
    Applicant: NOVARTIS AG
    Inventors: Bruno GALLI, Jean-Marie GLANTZMANN, Arnaud GRANDEURY, Klaus-Peter MOLL, Martin MUELLER-ZSIGMONDY, Karsten PUTZBACH, Dirk SPICKERMANN, Hubert THOMA, Mike UFER
  • ACTIVE INGREDIENT CONTAINING STABILISED SOLID MEDICINAL FORMS AND METHODS FOR THE PRODUCTION THEREOF
    Publication number: 20220000785
    Abstract: The invention relates to solid medicinal forms containing at least one active ingredient and at least one pharmaceutically compatible, water soluble drying agent which is selected from the group consisting of trimagnesium dicitrate and/or calcium chloride, the solid medicinal form having a drying loss of at most 6% and a relative equilibrium moisture content of 25% or less. The invention also relates to solid medicinal forms containing a moisture-sensitive active ingredient and trimagnesium dicitrate.
    Type: Application
    Filed: September 17, 2021
    Publication date: January 6, 2022
    Applicant: Losan Pharma GmbH
    Inventors: Peter GRUBER, Dirk Spickermann
  • MODIFIED RELEASE FORMULATION
    Publication number: 20210069150
    Abstract: Drug products in the form of modified release formulations comprising the drug substance (?)-(3aR,4S,7aR)-4-Hydroxy-4m-tolylethynyl-octahydro-indole-1-carboxylic acid methyl ester (AFQ056), as well as processes for making such drug products are provided. The drug products are useful in treating patients with Parkinson's disease and exhibiting L-dopa induced dyskinesia.
    Type: Application
    Filed: June 10, 2020
    Publication date: March 11, 2021
    Inventors: Bruno GALLI, Jean-Marie GLANTZMANN, Arnaud GRANDEURY, Klaus-Peter MOLL, Martin MUELLER- ZSIGMONDY, Karsten PUTZBACH, Dirk SPICKERMANN, Hubert THOMA, Mike UFER
  • ACTIVE INGREDIENT CONTAINING STABILISED SOLID MEDICINAL FORMS AND METHODS FOR THE PRODUCTION THEREOF
    Publication number: 20200188303
    Abstract: The invention relates to solid medicinal forms containing at least one active ingredient and at least one pharmaceutically compatible, water soluble drying agent which is selected from the group consisting of trimagnesium dicitrate and/or calcium chloride, the solid medicinal form having a drying loss of at most 6% and a relative equilibrium moisture content of 25% or less. The invention also relates to solid medicinal forms containing a moisture-sensitive active ingredient and trimagnesium dicitrate.
    Type: Application
    Filed: February 20, 2020
    Publication date: June 18, 2020
    Applicant: Losan Pharma GmbH
    Inventors: Peter GRUBER, Dirk Spickermann
  • Active ingredient containing stabilised solid medicinal forms and methods for the production thereof
    Patent number: 10603280
    Abstract: The invention relates to solid medicinal forms containing at least one active ingredient and at least one pharmaceutically compatible, water soluble drying agent which is selected from the group consisting of trimagnesium dicitrate and/or calcium chloride, the solid medicinal form having a drying loss of at most 6% and a relative equilibrium moisture content of 25% or less. The invention also relates to solid medicinal forms containing a moisture-sensitive active ingredient and trimagnesium dicitrate.
    Type: Grant
    Filed: December 7, 2018
    Date of Patent: March 31, 2020
    Assignee: Losan Pharma GmbH
    Inventors: Peter Gruber, Dirk Spickermann
  • ACTIVE INGREDIENT CONTAINING STABILISED SOLID MEDICINAL FORMS AND METHODS FOR THE PRODUCTION THEREOF
    Publication number: 20190105273
    Abstract: The invention relates to solid medicinal forms containing at least one active ingredient and at least one pharmaceutically compatible, water soluble drying agent which is selected from the group consisting of trimagnesium dicitrate and/or calcium chloride, the solid medicinal form having a drying loss of at most 6% and a relative equilibrium moisture content of 25% or less. The invention also relates to solid medicinal forms containing a moisture-sensitive active ingredient and trimagnesium dicitrate.
    Type: Application
    Filed: December 7, 2018
    Publication date: April 11, 2019
    Applicant: Losan Pharma GmbH
    Inventors: Peter GRUBER, Dirk Spickermann
  • Active ingredient containing stabilised solid forms and method for the production thereof
    Patent number: 10206879
    Abstract: The invention relates to solid medicinal forms containing at least one active ingredient and at least one pharmaceutically compatible, water soluble drying agent which is selected from the group consisting of trimagnesium dicitrate and/or calcium chloride, the solid medicinal form having a drying loss of at most 6% and a relative equilibrium moisture content of 25% or less. The invention also relates to solid medicinal forms containing a moisture-sensitive active ingredient and trimagnesium dicitrate.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: February 19, 2019
    Assignee: Losan Pharma GmbH
    Inventors: Peter Gruber, Dirk Spickermann
  • ACTIVE INGREDIENT CONTAINING STABILISED SOLID FORMS AND METHOD FOR THE PRODUCTION THEREOF
    Publication number: 20180000739
    Abstract: The invention relates to solid medicinal forms containing at least one active ingredient and at least one pharmaceutically compatible, water soluble drying agent which is selected from the group consisting of trimagnesium dicitrate and/or calcium chloride, the solid medicinal form having a drying loss of at most 6% and a relative equilibrium moisture content of 25% or less. The invention also relates to solid medicinal forms containing a moisture-sensitive active ingredient and trimagnesium dicitrate.
    Type: Application
    Filed: September 15, 2017
    Publication date: January 4, 2018
    Applicant: Losan Pharma GmbH
    Inventors: Peter Gruber, Dirk Spickermann
  • Stabilized solid medicinal forms containing active ingredient and method for the production thereof
    Patent number: 9775807
    Abstract: The invention relates to solid medicinal forms containing at least one active ingredient and at least one pharmaceutically compatible, water soluble drying agent which is selected from the group consisting of trimagnesium dicitrate and/or calcium chloride, the solid medicinal form having a drying loss of at most 6% and a relative equilibrium moisture content of 25% or less. The invention also relates to solid medicinal forms containing a moisture-sensitive active ingredient and trimagnesium dicitrate.
    Type: Grant
    Filed: September 14, 2007
    Date of Patent: October 3, 2017
    Assignee: Losan Pharma GmbH
    Inventors: Peter Gruber, Dirk Spickermann
  • MODIFIED RELEASE FORMULATION
    Publication number: 20160128979
    Abstract: Drug products in the form of modified release formulations comprising the drug substance (-)-(3aR,4S,7aR)-4-Hydroxy-4m-tolylethynyl-octahydro-indole-1-carboxylic acid methyl ester (AFQ056), as well as processes for making such drug products are provided. The drug products are useful in treating patients with Parkinson's disease and exhibiting L-dopa induced dyskinesia.
    Type: Application
    Filed: June 11, 2014
    Publication date: May 12, 2016
    Inventors: Bruno GALLI, Hubert THOMA, Arnaud GRANDEURY, Dirk SPICKERMANN, Karsten PUTZBACH, Klaus-Peter MOLL, Mike UFER, Jean-Marie GLANTZMANN, Martin MUELLER-ZSIGMONDY
  • ACTIVE INGREDIENT CONTAINING STABILISED SOLID MEDICINAL FORMS AND METHOD FOR THE PRODUCTION THEREOF
    Publication number: 20090270515
    Abstract: The invention relates to solid medicinal forms containing at least one active ingredient and at least one pharmaceutically compatible, water soluble drying agent which is selected from the group consisting of trimagnesium dicitrate and/or calcium chloride, the solid medicinal form having a drying loss of at most 6% and a relative equilibrium moisture content of 25% or less. The invention also relates to solid medicinal forms containing a moisture-sensitive active ingredient and trimagnesium dicitrate.
    Type: Application
    Filed: September 14, 2007
    Publication date: October 29, 2009
    Inventors: Peter Gruber, Dirk Spickermann