Patents by Inventor Dirk WEDEKIND

Dirk WEDEKIND has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MUTATION FOR TYPE I DIABETES MELLITUS AND ANIMAL MODEL
    Publication number: 20170164589
    Abstract: The invention relates to a mutation in the Dock8 encoding gene that is causative for type 1 diabetes mellitus at least in the rat (rattus norvegicus) or mouse, the rat or mouse preferably having an MHC predisposing towards type 1 diabetes mellitus and/or a mutation in the von Willebrand factor Vwa2. Embodiments of the invention comprise a process for generating a non-human mammal by genetic manipulation to contain at least heterozygously, preferably homozygously, the mutation causative for type 1 diabetes mellitus, preferably in combination with an MHC predisposing for type 1 diabetes mellitus and/or with a mutation in the von Willebrand factor Vwa2.
    Type: Application
    Filed: May 5, 2015
    Publication date: June 15, 2017
    Inventors: Sigurd LENZEN, Anne JOERNS, Dirk WEDEKIND, Tanja ARNDT