Patents by Inventor Disa TEHLER

Disa TEHLER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OLIGONUCLEOTIDE AGONISTS TARGETING PROGRANULIN
    Publication number: 20250136984
    Abstract: The present invention relates to oligonucleotides which up-regulate or restore the expression of progranulin in cells, and their use in the treatment of neurological disorders, and disorders associated with progranulin haploinsufficiency.
    Type: Application
    Filed: October 2, 2024
    Publication date: May 1, 2025
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Ravi JAGASIA, Lars JOENSON, Søren RASMUSSEN, Disa TEHLER, Dorthe Vang LARSEN, Jesper WORM
  • Antisense Oligonucleotide for Targeting Progranulin
    Publication number: 20250051772
    Abstract: The present invention relates to oligonucleotides which alter the splicing pattern of progranulin in cells, and their use in the treatment of neurological disorders.
    Type: Application
    Filed: August 20, 2024
    Publication date: February 13, 2025
    Inventors: Ravi Jagasia, Lars Jonson, Soren Rasmussen, Jacob Ravn, Disa Tehler, Dorthe Vang, Jesper Worm
  • Oligonucleotide agonists targeting progranulin
    Patent number: 12203071
    Abstract: The present invention relates to oligonucleotides which up-regulate or restore the expression of progranulin in cells, and their use in the treatment of neurological disorders, and disorders associated with progranulin haploinsufficiency.
    Type: Grant
    Filed: May 13, 2021
    Date of Patent: January 21, 2025
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Ravi Jagasia, Lars Joenson, Søren Rasmussen, Disa Tehler, Dorthe Vang Larsen, Jesper Worm
  • Antisense oligonucleotide for targeting progranulin
    Patent number: 12104153
    Abstract: The present invention relates to oligonucleotides which alter the splicing pattern of progranulin in cells, and their use in the treatment of neurological disorders.
    Type: Grant
    Filed: December 16, 2021
    Date of Patent: October 1, 2024
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Ravi Jagasia, Lars Jonson, Soren Rasmussen, Jacob Ravn, Disa Tehler, Dorthe Vang, Jesper Worm
  • Oligonucleotide Agonists Targeting Progranulin
    Publication number: 20230287412
    Abstract: The present invention relates to oligonucleotides which up-regulate or restore the expression of progranulin in cells, and their use in the treatment of neurological disorders, and disorders associated with progranulin haploinsufficiency.
    Type: Application
    Filed: November 14, 2022
    Publication date: September 14, 2023
    Inventors: Ravi Jagasia, Lars Joenson, Soren Rasmussen, Disa Tehler, Dorthe Vang Larsen, Jesper Worm
  • Antisense Oligonucleotide for Targeting Progranulin
    Publication number: 20220204973
    Abstract: The present invention relates to oligonucleotides which alter the splicing pattern of progranulin in cells, and their use in the treatment of neurological disorders.
    Type: Application
    Filed: December 16, 2021
    Publication date: June 30, 2022
    Inventors: Ravi Jagasia, Lars Jonson, Soren Rasmussen, Jacob Ravn, Disa Tehler, Dorthe Vang, Jesper Worm
  • OLIGONUCLEOTIDE AGONISTS TARGETING PROGRANULIN
    Publication number: 20210388357
    Abstract: The present invention relates to oligonucleotides which up-regulate or restore the expression of progranulin in cells, and their use in the treatment of neurological disorders, and disorders associated with progranulin haploinsufficiency.
    Type: Application
    Filed: May 13, 2021
    Publication date: December 16, 2021
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Ravi JAGASIA, Lars JOENSON, Søren RASMUSSEN, Disa TEHLER, Dorthe Vang LARSEN, Jesper WORM