Abstract: Techniques for a service provider network to divide computing resources of availability zones into smaller, isolated partitions (or “cells”), and manage the placement of virtual computing resources into the cells to reduce overconsumption of computing resources in the cells while ensuring ensure resiliency and availability. As virtual computing resources are launched into cells, or migrated between cells, the service provider network may load balance the virtual computing resources on a per-user basis to ensure resiliency and availability across the cells. Further, the service provider network may monitor the number of mutations (e.g., an operation that affects the state of a virtual computing resource) in each cell, as well as utilization rates of the underlying computing resources, and load balance virtual computing resource to maintain stable mutation rates and reduce over utilization (and/or under-utilization) of computing resources.