Patents by Inventor Ditlev Brodersen

Ditlev Brodersen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystal structure of the 30S ribosome and its use
    Publication number: 20050154538
    Abstract: The invention provides an X-ray crystal structure of the 30S ribosome, obtained from Thermus thermophilus 30S subunit, having a tetragonal space group P41212 with unit cell dimensions of a=401.4±4.0 ?, b=401.4±4.0 ?, c=175.9±5.0 ?. An advantageous feature of the structure is that it diffracts beyond 3 ? resolution. The invention also provides a crystal of 30S having the three dimensional atomic coordinates of the 30S ribosome, the coordinates being provided in Tables 1A and 1B. The data may be used for the rational design and modelling of inhibitors for the 30S ribosome, which have potential use as antibiotics.
    Type: Application
    Filed: September 17, 2001
    Publication date: July 14, 2005
    Inventors: Venkatraman Ramakrishnan, Brian Wimberly, William Clemons, Ditlev Brodersen, Andrew Carter