Patents by Inventor Divakar Ramakrishnan

Divakar Ramakrishnan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FORMULATION AND DELIVERY OF MODIFIED NUCLEOSIDE, NUCLEOTIDE, AND NUCLEIC ACID COMPOSITIONS
    Publication number: 20190142971
    Abstract: The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity.
    Type: Application
    Filed: July 31, 2018
    Publication date: May 16, 2019
    Inventors: Stephen G. Hoge, Örn Almarsson, David D. Hile, Ciáran Lawlor, John Podobinski, Staci Sabnis, Antonin De Fougerolles, Divakar Ramakrishnan, Kristy M. Wood
  • Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions
    Patent number: 10258698
    Abstract: The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: April 16, 2019
    Assignee: ModernaTX, Inc.
    Inventors: Stephen G. Hoge, Örn Almarsson, David D. Hile, Ciarán Lawlor, John Podobinski, Staci Sabnis, Antonin de Fougerolles, Divakar Ramakrishnan, Kristy M. Wood
  • Enzymes and polymerases for the synthesis of RNA
    Patent number: 9790531
    Abstract: The invention relates to compositions and methods for the design, evolution, preparation, and/or manufacture of enzymes for use with polynucleotides, primary transcripts and mmRNA molecules.
    Type: Grant
    Filed: November 18, 2016
    Date of Patent: October 17, 2017
    Assignee: ModernaTX, Inc.
    Inventors: Yuxun Wang, Divakar Ramakrishnan, Antonin De Fougerolles, Susan Whoriskey
  • ENZYMES AND POLYMERASES FOR THE SYNTHESIS OF RNA
    Publication number: 20170130255
    Abstract: The invention relates to compositions and methods for the design, evolution, preparation, and/or manufacture of enzymes for use with polynucleotides, primary transcripts and mmRNA molecules.
    Type: Application
    Filed: November 18, 2016
    Publication date: May 11, 2017
    Applicant: ModernaTX, Inc.
    Inventors: Yuxun Wang, Divakar Ramakrishnan, Antonin De Fougerolles, Susan Whoriskey
  • Enzymes and polymerases for the synthesis of RNA
    Patent number: 9512456
    Abstract: The invention relates to compositions and methods for the design, evolution, preparation, and/or manufacture of enzymes for use with polynucleotides, primary transcripts and mmRNA molecules.
    Type: Grant
    Filed: August 13, 2013
    Date of Patent: December 6, 2016
    Assignee: ModernaTX, Inc.
    Inventors: Yuxun Wang, Divakar Ramakrishnan, Antonin de Fougerolles, Susan Whoriskey
  • CHIMERIC POLYNUCLEOTIDES
    Publication number: 20160194625
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of chimeric polynucleotide molecules.
    Type: Application
    Filed: September 3, 2014
    Publication date: July 7, 2016
    Inventors: Stephen G. HOGE, Andrew W. FRALEY, Divakar RAMAKRISHNAN
  • FORMULATION AND DELIVERY OF MODIFIED NUCLEOSIDE, NUCLEOTIDE, AND NUCLEIC ACID COMPOSITIONS
    Publication number: 20160038612
    Abstract: The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 11, 2016
    Inventors: Stephen G. Hoge, Öm Almarsson, David D. Hile, Ciarán Lawlor, John Podobinski, Staci Sabnis, Antonin de Fougerolles, Divakar Ramakrishnan, Kristy M. Wood
  • ENZYMES AND POLYMERASES FOR THE SYNTHESIS OF RNA
    Publication number: 20150211039
    Abstract: The invention relates to compositions and methods for the design, evolution, preparation, and/or manufacture of enzymes for use with polynucleotides, primary transcripts and mmRNA molecules.
    Type: Application
    Filed: August 13, 2013
    Publication date: July 30, 2015
    Inventors: Yuxun Wang, Divakar Ramakrishnan, Antonin de Fougerolles, Susan Whoriskey