Abstract: The present invention discloses an advance methodology for using supplementary and secondary alignments to improve compression of genomic alignment file and method for exploiting information redundancies that exist in a between a primary alignment and secondary or supplementary alignments of the same read, to improve the compression of aligned genomic data. The method is implemented to compress SAM/BAM files, but in the future, it could be used to compress other file formats of aligned genomic data.

Abstract: A method for establishing credentials for securing text message communications. The method includes receiving, at a text messaging hub executing at a server device, a text message from a user, the text message being directed to a service number and including (1) a user number and (2) a request to establish a secure credential for communicating with a text messaging application. The method also includes transmitting, by the text messaging hub executing at the server device, an initiation message to the user, the initiation message includes a user-specific system number to which the user is to direct future text messages.