Abstract: A RollingCache system and methodology defends against contention side-channel cache attacks by dynamically changing the set of addresses contending for cache sets. Unlike prior defenses, RollingCache system does not rely on address encryption, decryption, data relocation, or cache partitioning. One or more levels of indirection are used to implement dynamic mapping controlled by the whole-cache runtime behavior. The RollingCache system does not depend on having defined security domains and can defend against an attacker running on the same or another core.

Abstract: The present invention discloses a novel engineered peptides P3T, P7T, P8T, P9T, P13T and P8_d1 of Seq ID No. 1 to combinations comprising one or more said peptides and compositions comprising one or more said peptides with pharmaceutically acceptable carriers and excipients and their use. The peptides and composition comprising said peptides induce autophagy by binding the protein GAPR-1 (?ve regulator of autophagy). Endogenously, GAPR-1 acts by tethering critical autophagy protein Beclin-1 (+ve regulator of autophagy) at the golgi and arrest autophagy. The peptide reported here binds GAPR-1 to free Beclin-1 and subsequently induce autophagy. The peptide can be used to induce or enhance autophagy and finds therapeutic application in a broad spectrum of disease pathologies that benefit from augmented autophagy, including obesity, diabetes, NASH, cancer, cardiomyopathy, neurodegenerative diseases, IBD and pathogenic infections.