Patents by Inventor Diwakar Shukla

Diwakar Shukla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PLANT SWEET AND YEAST MSF TRANSPORTER CAPABLE OF TRANSPORTING DIFFERENT SUGARS SIMULTANEOUSLY
    Publication number: 20230175021
    Abstract: The present disclosure provides genetically engineered microorganisms for the simultaneous fermentation of pentose and hexose sugars, for example, glucose and xylose. The microorganisms can be modified to express AtSWEET polypeptides, LST1 polypeptides, mutants thereof, homologs thereof or combinations thereof. Also provided are methods of co-fermenting hexose and pentose sugars, methods of increasing the conversion of lignocellulosic biomass via microbial fermentation, and methods of generating biofuel.
    Type: Application
    Filed: April 9, 2021
    Publication date: June 8, 2023
    Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventors: Yong-Su JIN, Nurzhan KUANYSHEV, Jing-Jing LIU, Anshu DEEWAN, Christopher V. RAO, Balaji PANNEERSELVAM, Diwakar SHUKLA, Sujit JAGTAP
  • Dendrimer-based excipients for the attenuation of protein aggregation
    Patent number: 9410142
    Abstract: One aspect of the invention is a salt comprising guanidinium groups, as shown in formula I. Another aspect of the invention is a salt comprising guanidinium groups, as shown in formula II. Another aspect of the invention is a salt comprising guanidinium groups, as shown in formula III. Another aspect of the invention is a salt comprising guanidinium groups, as shown in formula IV. Yet another aspect of the invention is a salt comprising guanidinium groups, as shown in formula I, II, III, and IV further comprising independently for each occurrence citrate, phosphate, or sulfate anion. Also disclosed are compositions comprising a protein and a salt comprising guanidinium groups, as shown in formula I, II, III, and IV. Also provided are methods of increasing shelf life of an aqueous solution of a protein and decreasing the amount of protein aggregation in an aqueous solution of a protein.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: August 9, 2016
    Assignee: Massachusetts Institute of Technology
    Inventors: Bernhardt L. Trout, II, Diwakar Shukla, Curtiss P. Schneider
  • Dendrimer-Based Excipients for the Attenuation of Protein Aggregation
    Publication number: 20140004592
    Abstract: One aspect of the invention is a salt comprising guanidinium groups, as shown in formula I. Another aspect of the invention is a salt comprising guanidinium groups, as shown in formula II. Another aspect of the invention is a salt comprising guanidinium groups, as shown in formula III. Another aspect of the invention is a salt comprising guanidinium groups, as shown in formula IV. Yet another aspect of the invention is a salt comprising guanidinium groups, as shown in formula I, II, III, and IV further comprising independently for each occurrence citrate, phosphate, or sulfate anion. Also disclosed are compositions comprising a protein and a salt comprising guanidinium groups, as shown in formula I, II, III, and IV. Also provided are methods of increasing shelf life of an aqueous solution of a protein and decreasing the amount of protein aggregation in an aqueous solution of a protein.
    Type: Application
    Filed: November 11, 2011
    Publication date: January 2, 2014
    Applicant: Massachusetts Institute of Technology
    Inventors: Bernhardt L. Trout, II, Diwakar Shukla, Curtiss P. Schneider